The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)

Session information

Symposium

[S29] Supersulfides in environmental toxicology and hygiene

Sun. Mar 26, 2023 4:00 PM - 6:00 PM [Room HS1] (1F)

Organizer: Takashi Toyama, Kazuhiro Nishiyama

Intrinsically produced supersulfur molecules (supersulfides), in which sulfur atoms are continuously bonded, have recently attracted attention for their physiological effects. It has been pointed out that supersulfation of cysteine increases the reactivity of thiol groups and may increase antioxidant activity and reactivity with medicinal toxicants, and may be an important regulatory factor, especially in toxicity and cell death caused by redox imbalance in vivo. Although it is well known that supersulfur is involved in various biological phenomena and pathological phenomena such as inflammation, this symposium will bring together young researchers in redox toxicology, hygienic pharmacology, and dynamics analysis of supersulfur in particular to discuss the significance of supersulfur. We will also present the latest findings on the unique pathways of supersulfur production in vivo. Through this symposium, we hope to renew the existing understanding of the role of transsulfur in toxicology and to deepen our understanding of the potential for new research developments.

オーガナイザー挨拶:外山 喬士(東北大院薬) (4:00 PM - 4:10 PM)

総括:西山 和宏(九大院薬) (5:50 PM - 6:00 PM)

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