[26P1-pm1-042] Development of aggregation-induced organic fluorescent molecules with high luminous properties

○Masayori Hagimori¹, Fumiko Hara¹, Tatsusada Yoshida², Yukiko Ogawa², Keitaro Tanaka³ (1. Sch. Pharm., Mukogawa Women’s Univ., 2. Fac. Pharm. Sci., Nagasaki Int. Univ., 3. Shimonoseki Med. Ctr)

[26P1-pm1-043] Synthesis and characterization of helical pyrylium salts

○Kazuteru Usui¹, Ryosuke Eto¹, Riku Arino¹, Shota Matsumoto¹, Tomohiro Umeno¹, Satoru Karasawa¹ (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-044S] Synthesis and characterization of dihydroaza[5]helicenes

○Kazuho Ishii¹, Satsuki Murase¹, Tomohiro Umeno¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-045S] Aqueous Self-assembly Behavior and Physical Properties of NO Radicals with Five-membered Ring

○Yuika Akizuki¹, Naoko Iizuka¹, Tomohiro Umeno¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Faculty of Pharm.Sci., Showa Pharm.Univ.)

[26P1-pm1-046] Preparations, X-ray structures, and physical properties of NO radicals bearing polar substituents

○Naoko iizuka¹, Ryoma Shiraishi², Tomohiro Umeno¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Grad. Sch. Pharm. Sci., Showa Pharmacetuical Univ., 2. Grad. Sch. Pharm. Sci., Kyushu Univ.)

[26P1-pm1-047] Non-preparative structure analysis of trace organic impurities in a pharmaceutical material by DNP-NMR technique

○Tomohiko Ueda¹, Yoshiaki Takai¹, Ayaka Maeno², Katsuaki Suzuki², Hironori Kaji² (1. Sumitomo Pharma Analytical Research & Development Laboratories, 2. Institute for Chemical Research, Kyoto University)

[26P1-pm1-048] The role of structural dynamics in ligand binding of the nuclear receptor PPARγ

○Kohei Tainaka¹, Takuya Yoshida¹, Rina Iwamoto¹, Tomohito Hanaoka¹, Kazuki Kawahara¹, Tadayasu Ohkubo¹ (1. Grad. Sch of Pharm. Osaka Univ.)

[26P1-pm1-049] Study on the development of a reversible fluorescence labeling reagent for amines based on the formation of enamines

○Tomohiro Umeno¹, Tomoki Kawahara¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Showa Pharmaceutical University)

[26P1-pm1-050S] Application of amine detection reagents toward solid-phase peptide synthesis using chromophore with HCl salt

○Moeka Fujihara¹, Tomohiro Umeno¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Faculty of Pharm.Sci., Showa Pharm. Univ.)

[26P1-pm1-051S] Development halogenated naphthyridine as fluorescent labeling reagents with intense emission in aqueous environment

○Lisa Muroi¹, Tomohiro Umeno¹, Kazuteru Usui¹, Satoru Karasawa¹ (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-052S] Self-Assembly Behavior and Characterization of Emissive Imidazonaphthyridine Derivatives

○Shota Matsumoto¹, Tomohiro Umeno², Kazuteru Usui², Koichi Hamada², Akihiro Mizutani², Satoru Karasawa² (1. Grad. Sch. Pharm. Sci., Showa Pharm. Univ., 2. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-053S] Aqueous Self-assembly Behavior for Hexaazapentacene Derivatives with Intense Emission

○Kanae Baba¹, Tokimi Oyama¹, Taro Saito¹, Tomohiro Umeno¹, Yasufumi Fuchi², Kazuteru Usui¹, Satoru Karasawa¹ (1. Faculty of pharm.Sci.,Showa pharm. Univ., 2. Faculty of pharm.Sci.,Tokushima Bunri pharm.)

[26P1-pm1-054S] Investigation of electrochemical measurement system to search for redox control substances of water-insoluble quinone

○Sawa Hayashi¹, Riko Miyaki¹, Kaoru Terao¹, Nao Okamoto¹, Noriko Okumura¹ (1. Kinjo Gakuin University )

[26P1-pm1-055S] Electrochemical approach for predicting the cytotoxicity of polyphenols

○Riko Miyaki¹, Utano Ohno¹, Sawa Hayashi¹, Yuki Ichinose¹, Kaori Suzuki¹, Noriko Okumura¹ (1. Kinjo Gakuin University)

[26P1-pm1-056S] Complex Formation of Rosmarinic acid and Berberin in Aqueous Solution

○Yoshiyuki Akita¹, Hiroyuki Tsutsumi¹, Rie Nakashima¹, Tomonori Ohata¹, Hirohito Ikeda¹ (1. Fac.Pharm.Sci., Fukuoka Univ.)

[26P1-pm1-057S] Development of Separation Method for (-)-Epigallocatechin-3-O-gallate and (-)-Epigallocatechin Using Cucurbit[7]uril

○An Miura¹, Hiroyuki Tsutsumi¹, Rie Nakashima¹, Tomonori Ohata¹, Hirohito Ikeda¹ (1. Fac. Pharm. Sci., Fukuoka Univ.)

[26P1-pm1-058S] Study on Formation of Inclusion Complex between Anti-herpesvirus Drugs and Cucurbit[7]uril

○Ryota Tsukiashi¹, Rie Nakashima¹, Hiroyuki Tsutsumi¹, Tomonori Ohata¹, Hirohito Ikeda¹ (1. Fac. Pharm.Sci., Fukuoka Univ.)

[26P1-pm1-059S] Improving water solubility of azithromycin using cyclodextrins and sugars

○Kana Yamada¹, Tomonori Ohata¹, Rie Nakashima¹, Hiroyuki Tsutsumi¹, Hirohito Ikeda¹ (1. Fac.Pharm.Sci.,Fukuoka Univ)

[26P1-pm1-060S] Comparison of Content of Dissolution and Crystallization Forms of Active Ingredients in Steroid Ointments : Triamcinolone Acetonide Ointment

○Yuta Kawabe¹, Tomonori Ohata¹, Rie Nakashima¹, Hiroyuki Tsutsumi¹, Hirohito Ikeda¹ (1. Fac. Pharm. Sci., Fukuoka Univ.)

[26P1-pm1-061] Analysis of the secondary structure of Rab12, a protein implicated in the pathogenesis of Parkinson’s disease, and its phosphorylation by LRRK2

○GENTA ITO¹, Ryo Nakamura¹, Naoko Utsunomiya-Tate¹ (1. Faculty of Pharma-Science, Teikyo Univ.)

[26P1-pm1-062S] Effects of amyloid beta-peptides on the serotonin-mediated copper reduction

○Takumi Kurihara¹, Risa Aoyagi¹, Saki Anata¹, Takashi Miura¹ (1. Dep. Pharm. Sci. Int. Univ. Health & Welfare)

[26P1-pm1-063] Structural change and aggregation by asparagine deamidation in γS-crystallin

○koichi kato^1,2,3, tomoki nakayoshi^2,4, Eiji Kurimoto², akifumi oda^2,5, yoshinobu ishikawa¹ (1. Pharm. Sci., Shonan Univ. of Med. Sci, 2. Facul. of Pharm., Meijo Univ., 3. Coll. of pharm., Kinjo Gakuin Univ., 4. Grad. Inf. Sci., Hiroshima City Univ., 5. Inst. Prot. Res., Osaka Univ.)

[26P1-pm1-064] Influences of chemical modifications on the structural properties and amyloid fibril formation of human serum amyloid A

○Masafumi TANAKA¹, Toru Takarada¹, Toshiyuki Yamada², Satomi Nadanaka¹, Hiroshi Kitagawa¹ (1. Kobe Pharm. Univ., 2. Jichi Med. Univ.)

[26P1-pm1-065] A possible role for N-glycosylation in the cellular secretion and interacting protein of serum amyloid A4

○Toru Takarada¹, Rikako Fujinaka¹, Toshiyuki Yamada², Masafumi Tanaka¹ (1. Kobe Pharm. Univ., 2. Jichi Med. Univ.)

[26P1-pm1-066S] Kinetic Approach to the Mechanism of Zinc Finger Oxidation by Hydrogen Peroxide

○Yuri Kawahito¹, Kanae Kishi², Mayu Yokozeki¹, Yuka Nakagawa³, Mami Hamori⁴, Shigeru Negi¹ (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch. Med., Hiroshima Univ., 3. Grad. Sch. Sci., Hyogo Univ., 4. Faculty of Pharm., Kitasato Univ.)

[26P1-pm1-067S] Identification and characterization of middle molecular weight compound inhibitors of Fcγ receptors

○Xu Pan¹, Tetsushi Hayakawa¹, Izumi Kato¹, Manabu Nagao¹, Takashi Tadokoro¹, Katsumi Maenaka¹ (1. Pharm. Sci., Hokkaido Univ.)

[26P1-pm1-068] Redox-independent conformational fluctuation near the active site of Escherichia coli DsbA studied by high-pressure NMR

○Ryo Kitahara^1,2, Junya Yamamoto², Soichiro Kitazawa¹, Yohei Miyanoiri³, Biswaranjan Mohanty⁴, Martin Scanlon⁵ (1. Col. Pharm. Sci., Ritsumeikan Univ., 2. Grad. Sch. Pharm. Sci. Ritsumeikan Univ., 3. IPR, Osaka Univ., 4. Univ. of Sydney, 5. Monash Univ.)

[26P1-pm1-069S] Novel ring formation by mutated human 20S proteasome alpha subunits

○Fuka Ikami¹, Shiori Kakiya¹, Keiichiro Imai¹, Yousuke Ryu¹, Akifumi Oda^1,2, Eiji Kurimoto¹ (1. Fac. Pharm. Meijo Univ., 2. Inst. Protein Res. Osaka Univ.)

[26P1-pm1-070S] Investigation of the importance of the number of amino acids between Cys residues in redox couples in vivo using zinc finger protein as a model.

○Mayu Yokozeki¹, Yuri Kawahito¹, Kanae Kishi², Yuka Nakagawa³, Mami Hamori⁴, Shigeru Negi¹ (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch. Med., Hiroshima Univ., 3. Grad. Sch. Sci., Hyogo Univ., 4. Faculty of Pharm., Kitasato Univ.)

[26P1-pm1-071] Functional analysis of activation domain of transcription factor Sp1

○Jun Kuwahara¹, Yuina Tsumori¹, Shunsuke Tajima¹, Masaru Hoshino², Katsumi Matsuzaki² (1. Fac. Pharm. Sci., Doshisha Women's Univ., 2. Grad. Sch. Pharm. Sci., Kyoto Univ.)

[26P1-pm1-072S] Physical property and amyloid-promoting effect of protein amyloid cofactor ApoA-IV

○Yoshito Naito¹, Norihiro Namba¹, Takashi Ohgida¹, Hiroyuki Saito¹ (1. Kyoto Pharm. Univ.)

[26P1-pm1-073S] Effect of amyloidogenic mutation on the structural stability and fibril-forming property of apoA-I

○Norihiro Namba¹, Miu Ueno¹, Hiroko Asahina¹, Takashi Ohgita¹, Toshinori Shimanouchi², Takeshi Sato¹, Hiroyuki Saito¹ (1. Kyoto Pharm. Univ., 2. Okayama Univ.)

[26P1-pm1-074S] Physicochemical evaluation of the reaction propensity of novel anti-apoE monoclonal antibody against apoE isoforms

○Koto Sakai¹, Nodoka Fukui¹, Norihiro Namba¹, Takashi Ohgita¹, Yuki Kiguchi², Izumi Morita², Hiroyuki Oyama², Kohjiro Nagao¹, Norihiro Kobayashi², Hiroyuki Saito¹ (1. Kyoto Pharm. Univ., 2. Kobe Pharm. Univ.)

[26P1-pm1-075] The analysis of the relationship between D-isomerization of amino acids in the tau microtubule-binding repeat and the fibrillation/aggregation

○Takuya Murata¹, Haruna Otsuka¹, Mana Yahagi¹, Rina Kokusyo¹, Genta Ito¹, Naoko Tate¹ (1. Fac. Pharm. Sci., Teikyo Univ.)

[26P1-pm1-076S] Quantitative evaluation of DNA repair mechanism involving PARP-1 using the QCM method

○Sakura Hosoi¹, Midori Tsuruta¹, Masato Mashimo¹, Hiroyuki Hurusawa², Shigeru Negi¹ (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch., Yamagata Univ)

Session information

[26P1-pm1] Structural chemistry, spectroscopy/Structure, physical property, and reactivity of biological materials/Biopolymers/Others