[26P1-am1-082S] Radiosynthesis of [¹⁸F]dFTAP1 for PET imaging of fatty acid binding protein 4

○Keita Wakamori¹, Anna Miyazaki¹, Yasukazu Kanai¹, Arisa Taguchi¹, Yoichiro Ohta², Satoru Onoe³, Hiromichi Akizawa³, Mitsunori Kirihata², Naoya Kondo¹, Takashi Temma¹ (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ. , 2. Osaka Metropolitan Univ. BNCT Reserch Center, 3. Facul. Pharm., Showa Pharm. Univ.)

[26P1-am1-083S] Synthesis and evaluation of SPECT probe with ¹¹¹In labeled-anti EphA2 antibody

○Minon Sasaki¹, Hiroyuki Kimura¹, Takenori Furukawa¹, Takumu Yamada², Takumi Iwasawa², Kazunori Kato², Hiroyuki Yasui¹ (1. Kyoto Pharm. Univ., 2. Dept. Biomedical Engineering, Toyo Univ.)

[26P1-am1-084] Optimization of automated radiosynthesis of [¹⁸F]FSW-100, an HDAC6 PET radioligand

○Tetsuro Tago¹, Jun Toyohara¹, Kenji Ishii¹ (1. TMIG)

[26P1-am1-085S] Research on development of [¹²⁵I]EFT-7 as an imaging tracer targeting Erythropoietin-producing hepatocellular receptor A2

○takenori furukawa¹, hiroyuki kimura¹, chika shiga¹, akane yoshimura¹, yusuke yagi^1,2, hidekazu kawashima¹, hiroyuki yasui¹ (1. Kyoto Pharm. Univ. , 2. Kyoto Pharm. Univ. Radioisotope Research Center)

[26P1-am1-086] Development of a STAT3-targeted PET imaging probe for tumor microenvironment evaluation

○Anna Miyazaki¹, Karen Ishimatsu¹, Yuuri Nishikawa¹, Yasukazu Kanai¹, Keita Wakamori¹, Shinya Takada¹, Fuko Hirano¹, Naoya Kondo¹, Takashi Temma¹ (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ.)

[26P1-am1-087] Development of [¹¹C]MeAIB synthesis on a cassette-type multipurpose automatic synthesizer module: Comparison between conventional and non HPLC procedure

○Shinya Kagawa¹, Kuninori Kusano¹, Miki Ito¹, Ryuichi Nishii^1,2, Tatsuya Higashi^1,2, Chio Okuyama¹ (1. Division of PET Imaging, Shiga Medical Center Research Institute, 2. Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST))

[26P1-am1-088S] Development of ¹⁹¹Pt-labeled compounds inducing DNA damage efficiently

○Honoka Obata^1,2, Atsushi B Tsuji¹, Kotaro Nagatsu¹, Mikako Ogawa², Ming Rong Zhang¹ (1. National Institutes for Quantum Science and Technology, 2. Grad. Sch. Pharm. Sci., Hokkaido Univ.)

[26P1-am1-089] Study on the chemical structure which is important for multivalent RGD peptides to form multiple bindings with integrin α_vβ₃

○Yuki Mizuno^1,2, Satoru Onoe³, Miho Shukuri³, Hiromichi Akizawa³, Yuji Kuge^1,2 (1. Cen. Inst. of Isot. Sci., Hokkaido Univ. , 2. Global Cen. for Biomed. Sci. and Engr., Hokkaido Univ. , 3. Showa Pharm. Univ.)

[26P1-am1-090] Preliminary screening of nanobodies for pancreatic cancer theranostics

○Takeshi Fuchigami¹, Tsukasa Kosugi^1,2, Yusuke Miyanari³, Ayako Tagawa³, Masayuki Munekane¹, Kenji Mishiro⁴, Sakura Yoshida², Akira Toriba², Morio Nakayama², Kazuma Ogawa^1,4 (1. Grad. Sch. Pharm., Kanazawa Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. WPI-NanoLSI, Kanazawa Univ., 4. InFiniti., Kanazawa Univ.)

[26P1-am1-091] Fully automated radiosynthesis of selective monoamine oxidase B tracer [¹⁸F]SMBT-1 for clinical use

○JUN TOYOHARA¹, Tetsuro Tago¹, Kosuke Nishino^1,2, Masanari Sakai^1,2, Kenji Ishii¹ (1. TMIG, 2. SAS)

[26P1-am1-092S] Development of nuclear medical imaging probe for systemic amyloidosis: drug design to reduce nonspecific accumulation in normal tissues

○Yoshie Haratake¹, Kohei Sano¹, Chika Fujioka¹, Satsuki Oshima¹, Masayuki Munekane^1,2, Toshihide Yamasaki¹, Takahiro Mukai¹ (1. Kobe Pharm. Univ., 2. Grad. Sch. Pharm., Kanazawa Univ.)

[26P1-am1-093S] Synthesis and evaluation of ¹¹¹In-DOTA-bradykinin analogue for bradykinin B1 receptor imaging.

○Tsubasa Karube¹, Miho Shukuri¹, Satoru Onoe¹, Risa Mokudai¹, Hayate Wakui¹, Haruka Asano¹, Shin Murai¹, Hiromichi Akizawa¹ (1. Showa Pharm. Univ.)

[26P1-am1-094] Effect of X-ray, proton, and carbon irradiation therapies on cervical cancers and early detection of their therapeutic effects by PET using ¹⁸F-FLT as an imaging tracer

○AKIRA MAKINO¹, KYO KUME², TETSUYA MORI¹, HIDEHIKO OKAZAWA¹, YASUSHI KIYONO¹ (1. Biomedical Imaging Research Center, University of Fukui, 2. The Wakasa-Wan Energy Research Center)

[26P1-am1-095] Accelerated blood clearance of radiolabeled antibody using click chemistry

○Hirofumi Hanaoka^1,2, Citra RAPP Palangka², Ayaka Kanai², Natsumi Katsumata², Hiroyuki Suzuki³, Tomoya Uehara³, Yoshito Tsushima² (1. Kansai Medical Univ., 2. Grad. Sch. Med., Gunma Univ., 3. Grad. Sch. Pharm. Sci., Chiba Univ.)

[26P1-am1-096] Development of radio-synthesis of 3-[¹⁸F]fluoro-α-methyl-L-tyrosine by nucleophilic fluorination with [¹⁸F]HF

○Naka Sadahiro^1,2, Watabe Tadashi¹, Ohta Yoichiro³, Kurimoto Kenta^1,2, Kinoshita Daisuke⁴, Wakahara Masaharu⁴, Yasuda Yuta⁴, Tatsumi Mitsuaki¹, Shimosegawa Eku¹, Kirihata Mitsunori³, Kato Hiroki¹ (1. Grad. Sch. Med., Osaka Univ., 2. Osaka Univ Hosp., 3. BNCT Res. Cent., Osaka Metropolitan Univ., 4. SHI Accelerator Service)

[26P1-am1-097S] Affinity Evaluation of Cystine-dense peptide TfRB1G3 for TfR1 and synthesis of HBED-CC conjugate for ⁶⁸Ga labeling.

○Lin Longxin¹, Mizuno Yuki^2,3, Kuge Yuji^2,3, Shibata Yuki³, Yasui Hironobu⁴ (1. Grad. Sch. Biomed. Sci. and Engr., Hokkaido Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr., Hokkaido Univ., 4. Fac. Vet. Med., Hokkaido Univ.)

[26P1-am1-098S] Effect of the number of RGD peptides introduced into albumin dimer on its in vivo behavior.

○Mao Sugita¹, Satoru Onoe¹, Kazuki Ooi¹, Yurika Kumakawa¹, Mizuki Kaneko¹, Yuki Mizuno^2,3, Miho Shukuri¹, Hiromichi Akizawa¹ (1. Showa Pharm. Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr.)

[26P1-am1-099S] Development of Glyoxalase I-targeted SPECT probes: metabolism of radioiodinated glutathione analogue-diester in cells

○Shiori Oba¹, Satoru Onoe¹, Kano Takadou¹, Yuki Mizuno^2,3, Miho Shukuri¹, Hiromichi Akizawa¹ (1. Showa Pharmaceutical Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr.)

[26P1-am1-100] Establishment of synthesis method of ¹¹C acetic acid using cassette type synthesizer and solid-phase extraction column

○KENTA KURIMOTO^1,2, SADAHIRO NAKA^1,2, MASAHARU WAKAHARA³, DAISUKE KINOSHITA³, YUTA YASUDA³, HIROKI KATO² (1. Department of Pharmacy, Osaka University Hospital, 2. Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 3. SHI Accelerator Service)

[26P1-am1-101S] Radioprotective effect of bone marrow cell by extracellular nucleotides

○Ayu Moriya¹, Kazuki Kitabatake¹, Mitsutoshi Tsukimoto¹ (1. Faculty of Pharm. Sci., Tokyo Univ. Sci.)

[26P1-am1-102] Specific radiation sensitization effect on cancer cells and radiation protection effect on normal cells via regulation of purinergic receptor activity

○Kazuki Kitabatake¹, Mitsutoshi Tsukimoto¹ (1. Faculty of Pharm Sci, Tokyo Univ. Sci.)

[26P1-am1-103S] Involvement of FROUNT in gamma-irradiation-induced cell migration in human lung cancer A549 cells

○Saya Tazawa¹, Yuya Terashima², Kazuki Kitabatake¹, Mitsutoshi Tsukimoto¹ (1. Faculty. Pharm. Sci., Tokyo Univ. Sci., 2. Grad. Sch. Biol. Sci., Tokyo Univ. of Sci.)

[26P1-am1-104] Local concentration of hydroxyl radical and hydrogen radical generated in water by X-ray irradiation and the effect of oxygen on the generation of those radical species

○Ken-ichiro Matsumoto¹, Yusuke Makino^1,2, Megumi Ueno¹, Yoshimi Shoji^1,3, Hiromu Ito³, Nakanishi Ikuo³, Koji Fukui² (1. NIRS, QST, 2. Grad. Sch. Eng. Sci, Shibaura Inst. Tech., 3. Inst. Quantum Life Sci., QST)

[26P1-am1-105] Analysis of subcellular localization of APOBEC3B after DNA damage

○Yohei Saito¹, Momoka Saito¹, Erina Fukushima¹, Yumi Yamamoto¹, Fumihiko Yamamoto¹ (1. Pharm. Sci., Tohoku Med. Pharm. Univ.)

[26P1-am1-106S] Effect of X ray-irradiation on amyloid-β-induced cytotoxicity

○Yuuka Nitta¹, Nakamura yuki¹, Kobayashi Yoshiko¹, Umeda tomonobu¹, katou Shinsuke¹ (1. YOKOHAMA UNIVERSITY OF PHARMACY)

[26P1-am1-107] Inhibition of cell death progression by X-ray irradiation

○Yuki Nakamura¹, Yuka Nitta¹, Kayo Aragaki¹, Nayu Hatano¹, Tomoko Matsuda¹, Yuna Miyazawa¹, Yudai Takagi¹, Tomonobu Umeda¹, Yoshiko Kobayashi¹, Shinsuke Katoh¹ (1. Yokohama University of pharmacy)

[26P1-am1-108] Suppression of cell death by X-ray irradiation in cerebral ischemia-reperfusion model

○Kayo Arakaki¹, Yudai Takagi¹, Yuna Miyazawa¹, Tomoko Matsuda¹, Nayu Hatano¹, Yuki Nakamura¹, Kobayashi Yoshiko¹, Umeda Tomonobu¹, Kato Shinsuke¹ (1. Yokohama University Of Pharmacy)

[26P1-am1-109S] In vitro and in vivo evaluation of boron drugs targeting Glucose transporter for BNCT

○Fumi Kimura¹, Seina Terada¹, Yuhki Sato¹, Minoru Suzuki², Takayuki Kanaya³, Makoto Shirakawa^1,4 (1. Pharm. Sci., Fukuyama Univ. , 2. Institute for Integrated Radiation and Nuclear Science, Kyoto Univ., 3. Pharm. Sci., Int. Univ. Health and Welfare, 4. Faculty of Medicine, Tsukuba Univ.)

[26P1-am1-110S] Development of Ionic Liquids Composed of BPA for Boron Neutron Capture Therapy

○Saki Kawamoto¹, Sayaka Kawakami¹, Tomonori Sakai¹, Riko Terada¹, Mimori Samejima¹, Yuhki Sato¹, Hiroaki Kumada², Takeji Sakae², Akira Matsumura², Nobuyuki Kamegawa³, Ryota Takeuchi³, Hitoshi Hori³, Minoru Suzuki⁴, Makoto Shirakawa^1,2 (1. Pharm. Sci., Fukuyama Univ., 2. Faculty Medicine, Tsukuba Univ., 3. Morita Pharmaceutical Ind.,Ltd, 4. Institute for Integrated Radiation and Nuclear Science, Kyoto Univ.)

[26P1-am1-111] Low dose radiation therapy of COVID-19

○Noriko Shimura¹, Koki Mochizuki¹, Shuji Kojima² (1. Faculty of Pharmaceutical Sciences, Ohu University, 2. Faculty of Pharmaceutical Sciences, Tokyo University of Science)

[26P1-am1-112] Glial energy metabolism in the neonatal mouse brain during convulsive seizures using intranasal administration.

○Rie Hosoi¹, Kenya Tada¹, Takahiro Hayakawa¹, Yuka Haga¹, Atsushi Tamura¹, Makoto Osanai¹ (1. Grad. Sch. Med., Osaka Univ.)

[26P1-am1-113S] Kinetic analysis on transporter-mediated cellular uptakes of 3-boronophenylalanine derivatives

○Fuko Hirano¹, Naoya Kondo¹, Yusuke Murata², Aya Sudani², Takashi Temma¹ (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ., 2. Stella Pharma Co.)

[26P1-am1-114S] Development of a red-emitting fluorescence sensor for detecting boronic acid-containing agents in cells

○Erika Aoki¹, Naoya Kondo¹, Shinya Takada¹, Takashi Temma¹ (1. Facul. Pharm., Osaka Med. Pharm. Univ.)

Session information

[26P1-am1] Radiochemistry