[26P2-pm1-001S] Analysis of synergistic interleukin-6 production mechanism induced by interferon-γ and poly(I:C) in human airway epithelial NCl-H292 cells.

○Norikazu Okuma^1,2, Masa-aki Itou¹, Kazuki Yoshida¹, Isao Matsuoka¹ (1. Grad. Sch. Pharm. Sci., Takasaki University of Health and Welfare, 2. Dept. Pharm.,Japan Community Health care Organization Gunma Chuo Hospital)

[26P2-pm1-002S] Effects of PGJ₂ on cAMP production via the human EP2 prostanoid receptors

○Mayu Yamashita¹, Hitomi Yamamoto¹, Mayu Shinohara¹, Keijo Fukushima¹, Akiko Suganami², Yutaka Tamura², Hiromichi Fujino¹ (1. Facult. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Med., Chiba Univ.)

[26P2-pm1-003S] EP4 prostanoid receptors mediated metabolic pathways

○Yuki Nakano¹, Kiyoka Matsumoto¹, Ayaka Ogimoto¹, Saki Someya¹, Keijo Fukushima¹, Hiromichi Fujino¹ (1. Facult. Pharm. Sci., Tokushima Univ.)

[26P2-pm1-004S] The phosphatase activity of soluble epoxide hydrolase maintains functional link between phospholipid turnover, kinase signaling and store Ca²⁺ handling in peritoneal macrophages

○Feng Liu¹, Keiji Hasumi^2,3, Hiroshi Takeshima¹ (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Grad. Sch. Agri., Tokyo Univ. Agric. Tech., 3. TMS Co., Ltd.)

[26P2-pm1-005S] Exploration of therapeutic targets for liver fibrosis based on the structure of transdifferentiation regulators of hepatic stellate cells

○Akira Ooka^1,5, Momoka Yamaguchi^1,2, Yuzuki Nagasawa³, Nanami Motohashi², Kenji Yamashita^1,3, Yoshitaka Hamashima^1,3, Shin-ya Saito⁴, Tomohisa Ishikawa^1,2 (1. Grad. Sch. Pharm. Sci., Univ. Shizuoka, 2. Dept. Pharmacol., Sch. Pharm. Sci., Univ. Shizuoka, 3. Dept. Synth. Org. Chem., Sch. Pharm. Sci., Univ. Shizuoka, 4. Fac. Vet. Med., Okayama Univ. Sci., 5. JSPS)

[26P2-pm1-006S] Elucidation of the mechanism of olanzapine-induced obesity pathogenesis -Involvement of leptin resistance-

○Riko Morimoto¹, Karen Kuriya¹, Shoko Sashiyama¹, Nana Inoue¹, Tadashi Nakagawa¹, Yasuhiro Noda¹, Toru Hosoi¹ (1. Fac. Pharm. Sci., Sanyo-Onoda City Univ.)

[26P2-pm1-007S] Effects of plasmalogen on the onset of Alzheimer's disease

○Haruka Okabayashi¹, Miki Yasuda¹, Chinatsu Nii¹, Keijo Fukushima¹, Kouki Yuasa², Satoshi Kotoura², Hiromichi Fujino¹ (1. Facult. Pharm. Sci., Tokushima Univ., 2. Cent. Res. Inst., Marudai Food Co. Ltd.)

[26P2-pm1-008S] Examination of the involvement of α2-antiplasmin in survival and maturation of transplanted neural progenitor cells

○Yuna Misaki¹, Eri Kawashita¹, Kaneyasu Nishimura¹, Keiichi Ishihara¹, Suzuka Noguchi¹, Kazuyuki Takata¹, Osamu Matsuo², Satoshi Akiba¹ (1. Kyoto Pharm. Univ., 2. Kinki Univ. Sch. of Med.)

[26P2-pm1-009S] Ameliorative effects of muscarine M₄receptor agonists on MK-801-induced cognitive impairment

○Yuto Ishizaki¹, Saki Shimizu¹, Yumika Toyoshima^1,2, Takaaki Sumiyoshi², Yukihiro Ohno¹ (1. Dept. Pharmacol., Fac. Pharmacy, Osaka Med. Pharm. Univ., 2. Grad. Sch. Dept. Life Sci. and Biotech., Kansai Univ.)

[26P2-pm1-010S] The stress sensitivity is determined by serotonergic system in the raphe nucleus through N-acetyltransferase.

○HAJIME MIYANISHI¹, SHIN-ICHI MURAMATSU^2,3, ATSUMI NITTA¹ (1. Grad. Pharm. Sci., Toyama Univ, 2. Open. Innov. Cen., Jichiika Univ, 3. Ins. Med. Sci., Tokyo Univ)

[26P2-pm1-011S] Effects of fluvoxamine on restraint stress-induced behavior by serotonin reduction at young stage (4 weeks)

○Takayuki Kobayashi¹, Gaku Hirose¹, Shiho Fukuda¹, Megumi Furukawa¹, Ryoken Aoki¹, Yuna Ishiyama¹, Masahiro Toho¹, Takeaki Nitto¹, Nobuo Izumo^1,2 (1. Yokohana University Of Pharmacy, 2. General Health Medical Research Center, Yokohama University of Pharmacy)

[26P2-pm1-012] The effects of aging and DHA supplementation on the sensitivity of pilocarpine-induced epileptic seizure in mice

○Motomi Imamura¹, Takuro Iwao¹, Yuko Kuriyama¹, Kakeru Arakaki¹, Fuyuko Takata¹, Shinya Dohgu¹ (1. Dept. Pharmaceut. Care & Health Sci., Fac. Pharmaceut. Sci., Fukuoka Univ.)

[26P2-pm1-013] The effect of DHA supplementation on the age-related Blood-Brain Barrier disruption

○Yuko Kuriyama¹, Takuro Iwao¹, Motomi Imamura¹, Kakeru Arakaki¹, Fuyuko Takata¹, Shinya Dohgu¹ (1. Dept. Pharmaceut. Care & Health Sci., Fac. Pharmaceut. Sci., Fukuoka Univ. )

[26P2-pm1-014] Effect of chronic dietary docosahexaenoic acid supplementation on motor coordination in aged mice

○Kakeru Arakaki¹, Takuro Iwao¹, Yuko Kuriyama¹, Motomi Imamura¹, Fuyuko Takata¹, Shinya Dohgu¹ (1. Dept. Pharmaceut. Care & Health Sci., Fac. Pharmaceut. Sci., Fukuoka Univ.)

[26P2-pm1-015] Characterization of Brain Pericytes derived from Human iPSCs

○Miki Yokoya¹, Yasuyoshi Tnaka^3,4,5, Fuyuko Takata², Junichi Matsumoto², Takuro Iwao², Miho Yasunaga¹, Mayu Shibata², Shinya Dohgu² (1. Grad. Sch. Pharm. Sci., Fukuoka Univ., 2. Dept. Phramacol. Fukuoka Univ., 3. Dept. Advanced Pharmacol. Daiichi Univ of Pharm., 4. iONtarget Co., Ltd., 5. General Medical Research Center, School of Medicine, Fukuoka Univ.)

[26P2-pm1-016] Activation of hippocampal microglia is involved in the development of depression-like behavior observed in animal model of olfactory dysfunction

○Kohei Takahashi¹, Minoru Tsuji¹, Osamu Nakagawasai², Soh Katsuyama³, Kazuhiro Kurokawa¹, Kazuya Miyagawa¹, Atsumi Mochida-Saito¹, Hiroshi Takeda⁴, Takeshi Tadano^2,5 (1. Sch. Pharm. Sci., International Univ. Health and Welfare, 2. Sch. Pharm. Sci., Tohoku Medical and Pharmaceutical Univ., 3. Nihon Pharmaceutical Univ., 4. Sch. Pharm. Sci., Fukuoka, International Univ. Health and Welfare, 5. Grad. Sch. Med. Sci., Kanazawa Univ.)

[26P2-pm1-017] Imipramine enhances interleikine-10 via MEF2D upregulation mediated by AKT-GSK3β pathway under inflammatory state

○YOSUKE YAMAWAKI¹ (1. Daiichi Univ. Pharm.)

[26P2-pm1-018] Roles of TRPC3 and TRPC6 in the medial prefrontal cortex in the antidepressant-like effects of ketamine

○Satoshi Deyama¹, Katsuyuki Kaneda¹ (1. Inst. Med., Pharmaceut., Health Sci., Kanazawa Univ.)

[26P2-pm1-019] NMN ameliorates rotenone-induced neurite outgrowth inhibition in PC12 cells

○Takahisa Nakajo¹, Takeshi Katayoshi¹, Natsuko Kitajima¹, Kentaro Naito¹ (1. DHC corporation)

[26P2-pm1-020] LRP1 protects optic nerves from NMDA-induced excitotoxicity associated with reducing α2-macroglobulin in Müller glia

○Hideki Hayashi¹, Misuzu Mori¹, Kanako Mise¹, Norio Takagi¹ (1. Sch. Pharm., Tokyo Univ. Pharm. Life Sci.)

[26P2-pm1-021] Development of mid-size molecule inhibitors of VIPR2 for the treatment of psychiatric disorders

○Yukio Ago¹, Mei Yamada², Tatsunori Miyaoka², Lu Chen², Kenji Ishimoto², Nobumasa Hino², Shinsaku Nakagawa², Kotaro Sakamoto³, Satoshi Asano¹ (1. Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 2. Grad. Sch. Pharmaceut. Sci., Osaka Univ., 3. Ichimaru Pharcos Co. Ltd.)

[26P2-pm1-022] Effects of the novel μ-opioid receptor non-peptide antagonist, UD-030, on the morphine-induced reward

○Soichiro Ide¹, Noriaki Iwase², Kenichi Arai², Masahiro Kojima², Shigeru Ushiyama², Kaori Taniko³, Kazutaka Ikeda¹ (1. TMiMS, 2. UBE Corporation, 3. Sanwa Kagaku Kenkyusho Co. Ltd.)

Session information

[26P2-pm1] Pharmacology 1