[26P2-pm1-023S] Differences of cytokines expression and the mechanisms between antigen triggered ABCA7 knock out mast cells and WT mast cells

○Hikari Sato¹, Reina Isomura¹, Mao Kawaguchi¹, Hinano Murai¹, Sayaka Ono¹, Anju Yamazaki¹, Sumiko Dohmae², Haruka Asai¹, Nobuyuki Fukuishi¹ (1. Dept. pharmacol. Coll. Pharm. Kinjo Gakuin Univ., 2. Dept. Biochem. Coll. Biosci. and Biotech. Chubu Univ.)

[26P2-pm1-024S] Role of the microsomal prostaglandin E synthase-1 in psoriasis

○Yuka Hioki^1,2, Hiroki Enomoto¹, Yu Onodera¹, Saki Miura¹, Hikaru Itabashi¹, Yoshiko Iizuka^3,4, Shotaro Maehana^3,5, Makoto Kubo^3,5, Takafumi Ichikawa^2,3, Fumiaki Kojima^1,2,3 (1. Department of Pharmacology, Kitasato University, Japan, 2. Department of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, Japan, 3. Regenerative Medicine and Cell Design Research Facility, Japan, 4. Department of Public Health, Kitasato University Graduate School of Medical Sciences, Japan, 5. Department of Environmental Microbiology, Kitasato University Graduate School of Medical Sciences, Japan)

[26P2-pm1-025S] Inhibitory effects of TRP channel inhibitors on the production of inflammatory cytokine by activation of Toll-like receptor 3/7

○Ayano Usami¹, Yohei Takenaka¹, Kazuki Kitabatake¹, Takato Takenouchi², Mitsutoshi Tsukimoto¹ (1. Faculty of Pharm. Sci., Tokyo Univ. Sci. , 2. Institute of Agrobiological Sciences, National Agriculture and Food Research Organization)

[26P2-pm1-026S] Roles of Tr1 cell-derived extracellular vesicles in the effect of allergen immunotherapy

○Shunsuke Nishiuma¹, MASAYA MATSUDA¹, KAZUYUKI KITATANI¹, TAKESHI NABE¹ (1. Fac. Pharm. Sci., Setsunan Univ)

[26P2-pm1-027S] Effect of a novel lactoferrin on dexamethasone- induced of thymic atrophy

○Gaku Hirose¹, Takayuki Kobayashi¹, Manami Namegaya¹, Akihiro Shibutani¹, Ryoken Aoki¹, Megumi Furukawa¹, Megumi Ono², Nobuo Izumo^1,3 (1. Yokohama University of Pharmacy, 2. NRL Pharma, Inc., 3. General Health Medical Research Center, Yokohama University of Pharmacy)

[26P2-pm1-028S] Inhibition of neurotoxic factor release dependent on timing of addition by lipid fraction derived from Pork Liver Decomposition Product

○Takamitsu Noguchi¹, Maeda Tomoji^1,2, Sonoda Ayaka², Hata Erina², Ishikawa Misuzu², Sitou Naoya², Hujita Toru³, Kurihara Taiga², Hanyu Hisao⁴, Tsukahara Kan⁵, Uemura Takeru⁴, Satou Wasaburo⁶, Matsuda Yosikazu^1,2 (1. Graduate School Nihon Pharmaceutical Univ. , 2. Nihon Pharmaceutical Univ., 3. Yokohama Univ. of Pharmacy, 4. Biomedical Institute of Shinshu Univ., 5. Nagasaki Univ., 6. Sugar Lady Cosmetics )

[26P2-pm1-029S] Involvement of CCR5⁺ interstitial macrophages in development of lung fibrosis of severe asthma

○Keitaro Nishikawa¹, Hayato Shimora¹, Itomi Takamori¹, Yukino Nagatani¹, Tenta Haguchi¹, Shota Sasaki¹, Masaya Matsuda¹, Kazuyuki Kitatani¹, Takeshi Nabe¹ (1. Fac. Pharm. Sci., Setsunan Univ.)

[26P2-pm1-030S] CCR4 antagonist ameliorated atopi dermatitis by inhibiting infiltration and expansion of CCR4-expressing Th2 cells and Th17 cells in mice

○Ayaka Yamashita¹, Kazuhiko Matsuo¹, Yoko Susami¹, Haruko Hayasaka², Yuta Hara¹, Takashi Nakayama¹ (1. Fac.Pharm.Kindai Univ., 2. Fac.Sci.Eng.Kindai Univ)

[26P2-pm1-031S] Correlation analysis of changes in gut microbiota composition and immune alterations under the condition of cancer cachexia

○Hina Miyata¹, Yukari Suda^1,2, Ryo Watanabe¹, Fukiko Matsuyama^1,3, Naoko Kuzumaki^1,2, Minoru Narita^1,2 (1. Dept. Pharmacol., Hoshi Univ., Tokyo, Japan, 2. Div. Pathophysiol., Natl. Cancer Ctr. Res. Inst., Tokyo, Japan, 3. Japan Small Animal Medical Center)

[26P2-pm1-032] Dose-dependent inhibition of neurotoxic factor release by lipid fraction derived from Pork Liver Decomposition Product

○Tomoji Maeda^1,2, Erina Hata², Takamitsu Noguchi¹, Ayaka Sonoda², Misuzu Ishikawa², Naoya Shito², Yu Fujita³, Taiga Kurihara², Hisao Haniu⁴, Tamotsu Tsukahara⁵, Takeshi Uemura⁴, Wasaburo Sato⁶, Yoshikazu Matsuda^1,2 (1. Grad.Sch.,Nihon Pharm. Univ, 2. Nihon Pharm. Univ, 3. Yokohama Pharm.Univ, 4. Biomedical Inst. of Shinshu Univ, 5. Sch. Pharm. Sci., Nagasaki Univ, 6. Sugar Lady Cosmetics)

[26P2-pm1-033] Immunomodulatory effect of rice-derived glucosylceramides and ceramides on innate immunity

○Kenchi Miyasaka¹, Yoshiaki Manse², Toshio Morikawa², Kiyoe Itoi³, Kazuo Miyazaki³, Hiroshi Shimoda¹ (1. Oryza Oil & Fat Chemical Co., Ltd., 2. Pharm. Res. Technol. Inst., Kindai Univ., 3. MiCAN Technologies, Inc.)

[26P2-pm1-034] PAI-1 release from breast cancer MCF-7 cells after transient treatment with chemotherapeutic agents

○Riyo Morimoto-Kamata¹, Shiori Ishikawa¹, Narumi Ohkawara¹, Naoki Ohkura¹ (1. Dep. of Parma-Sci., Teikyo Univ.)

[26P2-pm1-035] AKT activation by everolimus prevents doxorubicin-induced apoptosis in rat cardiac H9c2 cells

○Syu-ichi Kanno¹, Shin Yomogida¹, Akiyoshi Hara¹ (1. Fac. Pharm. Sci., Tohoku Med. Pharm. Univ.)

[26P2-pm1-036] Comparison of mTOR inhibitor action in breast cancer cells focusing on gene expression.

○Hiroyuki Okazaki¹, Ryo Tanaka¹, Taiga Ichiki¹, Yasutaka Suga¹, Ayaka Ueda¹, Saori Miyamura¹, Mariko Takenokuchi¹ (1. Daiichi Univ. Pharm.)

[26P2-pm1-037] A synthetic propiolamide derivative induces apoptosis in oral cancer cells

○Jing-Ru Weng¹, Balraj Gopula² (1. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, 2. Drug Development Center, China Medical University)

[26P2-pm1-038] CXCR4-mediated intracellular delivery of pro-apoptotic peptide induces a caspase-independent cell death

○Abraham Akonnor¹, Masaki Makise¹, Akihiko Kuniyasu¹ (1. Grad. Sch. Pharm. Sci., Sojo University)

[26P2-pm1-039S] Effects of plant-derived exosome-like nanoparticles on the activation of hepatic stellate cells

○Mayuki Okabe¹, Momoka Yamaguchi¹, Akira Ooka¹, Sumire Morino¹, Ryogo Shibata¹, Takanori Kanazawa², Yukiko Kaneko¹, Tomohisa Ishikawa¹ (1. Dept. Pharmacol., Sch.Pharm.Sci.,Univ.Shizuoka, 2. Dept. Pharm. Eng. DDS, Sch.Pharm.Sci.,Univ.Shizuoka)

[26P2-pm1-040S] Acute inflammation of gastric mucosa induced by allyl isothiocyanate in anesthetized rats

○Ryouhei Mochizuki¹, Marina Oshige¹, Kimihito Tashima¹, Syunji Horie¹ (1. Fac. Pharm. Sci., Josai. International Univ.)

[26P2-pm1-041S] Roles of TRPM2 in the pathogenesis of TNBS-induced colonic inflammation and fibrosis in mice

○Juna Koyoma¹, Tomohiro Nakamoto¹, Hiroyuki Yasuda¹, Kenjiro Matsumoto¹, Shinichi Kato¹ (1. Kyoto Pharmaceutical University)

[26P2-pm1-042S] PAD4 contributes to the pathogenesis of TNBS-induced colitis via extracellular traps

○Yoshiya Tanaka¹, Hiroyuki Yasuda¹, Ayaka Uno¹, Saya Kouda¹, Michiko Saito², Kenjiro Matsumoto¹, Shinichi Kato¹ (1. Div. Pathol. Sci., Dept. Pharmacol. Exp. Ther., Kyoto Pharm. Univ., 2. Bio-Sci. Res. Ctr., Kyoto Pharm. Univ.)

[26P2-pm1-043S] Nafamostat mesilate inhibits 5-hydroxytryptamine synthesis in the rat small intestine after methotrexate administration

○Takahiro Yamamoto¹, Takuji Machida¹, Chiho Tanno¹, Shiori Hasebe¹, Mayu Tamura¹, Sachiko Hiraide¹, Naoya Hamaue¹, Kenji Iizuka¹ (1. Sch. Pharm. Sci., Health Sci. Univ. Hokkaido)

[26P2-pm1-044] Comparative study of the effects of sodium ferrous citrate and ferric citrate hydrate on the number of enterochromaffin cells in rats

○TAKUJI MACHIDA¹, SACHIKO HIRAIDE¹, TAKAHIRO YAMAMOTO¹, SAKI SHIGA¹, KENJI IIZUKA¹ (1. Sch. Pharm. Sci, Health Sci. Univ. Hokkaido)

[26P2-pm1-045] Investigation of the mechanism of cytoprotection by heme oxygenase-1 against tamoxifen-induced cytotoxicity

○Takafumi Nakano¹, Anna Shimazu¹, Yuki Watanabe¹, Takasi Mizuma¹ (1. Fac. Pharm. Sci., Teikyo Heisei Univ.)

Session information

[26P2-pm1] Pharmacology 2