[27E2-pm] Chemical biology/Structure-activity relationship/Drug design

Mon. Mar 27, 2023 3:50 PM - 5:26 PM [Room E2]Institute for the Advancement of Higher Education: E308 (Bldg. E: 3F)

Chair: Yuji Ito, Ichiro Takasaki

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3:50 PM - 4:02 PM

[27E2-pm11S] Comprehensive Analysis of Peptidase Activities in Blood Using Peptide Library.

○Etsu Kyo¹, Toru Komatsu¹, Kazuhumi Honda³, Yasuteru Urano^1,2 (1. Grad. Sch. Pharm. Sci., Tokyo Univ., 2. Grad. Sch. Med., Tokyo Univ., 3. Nippon Med. School)

4:02 PM - 4:14 PM

[27E2-pm12S] Pharmacological effects on food intake and stress response of intranasally administered CPN-219, a neuromedin U receptor type 2 agonist

○Asuka Nomoto¹, Yui Suzuki¹, Katsuya Morito¹, Kazuki Nagasawa¹, Kentaro Takayama¹ (1. Kyoto Pharm. Univ.)

4:14 PM - 4:26 PM

[27E2-pm13S] Binding analysis of HIV-1 Gag MA domain to cardiolipin for drug discovery

○Takuma Chinen¹, Hiroshi Tateishi¹, Kazunori Shimagaki¹, Ryota Fukuda¹, Mohamed O Radwan¹, Arisa Sakamoto^1,2, Masami Otsuka^1,3, Mikako Fujita¹, Kensaku Anraku² (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. Kumamoto Health Science Univ. , 3. Science Farm Ltd.)

4:26 PM - 4:38 PM

[27E2-pm14S] Liquid-liquid phase separation formation by macromolecule delivery peptides bearing polysaccharides and its application for cytosolic antibody delivery.

○Junya Michibata¹, Yoshihiro Sasaki², Kazunari Akiyoshi², Shiroh Futaki¹ (1. Inst. Chem. Res., Kyoto Univ., 2. Grad. Sch. Eng., Kyoto Univ.)

4:38 PM - 4:50 PM

[27E2-pm15] Development of antibody-mimetic HER2-binding small proteins by Smart Design technology

○Tetsuya Kadonosono¹, Yutaka Saito², Ning Lin¹, Shinae Kondoh¹ (1. Tokyo Tech, 2. AIST)

4:50 PM - 5:02 PM

[27E2-pm16] Research of learning process of diverse chemical structures by natural language processing models

○Tadahaya Mizuno¹, Shumpei Nemoto¹, Yasuhiro Yoshikai¹, Kusuhara Hiroyuki¹ (1. Grad. Sch. Pharm. Sci., Tokyo Univ.)

5:02 PM - 5:14 PM

[27E2-pm17S] Design of antimicrobial peptides containing non-proteinogenic amino acids using Multi-objective Bayesian optimization

○Yuki Murakami¹, Shoichi Ishida¹, Yosuke Demizu^1,2, Kei Terayama¹ (1. Grad. Sch. Med. Life Sci., Yokohama City Univ., 2. NIHS)

5:14 PM - 5:26 PM

[27E2-pm18S] In silico design of peptides inhibiting Wnt/β-catenin pathway

○Minami Fujita^1,2, Keisuke Tsuchiya^2,3, Masato Kiyoshi², Akiko Ishii-Watabe², Takashi Misawa², Yosuke Demizu^1,2 (1. Grad. Sch. Med. Life Sci., Yokohama City Univ., 2. NIHS, 3. Grad. Sch. Pharm., Showa Univ.)

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