[27P2-pm1-035S] The kinetic analysis of liposomal formulation in a nephrotic model

○Tetsusaburo Saito¹, Sei Yonezawa¹, Tomohiro Asai¹ (1. 1.Grad. Sch. Pharm. Sci., Univ. Shizuoka)

[27P2-pm1-036S] Effect of CHAC1 in tubular cells on apoptosis induction in renal ischemia-reperfusion injury

○Yuka Uemura¹, Tomohisa Odagawa¹, Yoshitaka Kihira¹, Yoshino Fujimura¹, Eiji Satou¹ (1. Fac. Pharm. &Pharmaceut .Sci., Fukuyama Univ.)

[27P2-pm1-037] Roles of hypoxia-inducible factor in the development of dextran sulfate sodium-induced colitis

○Fujimura Yoshino¹, Sato Yui¹, Hanakawa Saki¹, Wakabayashi Miho¹, Kihira Yoshitaka¹, Sato Eiji¹ (1. Fac.Pharm&Pharmaceut.Sci.,Fukuyama Univ)

[27P2-pm1-038S] Lysophosphatidic acid induces inflammation in adipocytes via hypoxia-inducible factor-1α

○Ayako Morikawa¹, Mayuko Osada¹, Yoshino Fujimura¹, Yoshitaka Kihira¹, Eiji Sato¹ (1. Fac. Pharm. & Pharmaceut. Sci., Fukuyama Univ.)

[27P2-pm1-039] Involvement of AGN-1, which binds to protein phosphatase 6, in centrosome formation during cell division

○Misa Furukawa¹, Ru Kojima¹, Ryoji Kojima¹ (1. Meijo University)

[27P2-pm1-040] Development of novel human kidney cell model using human renal proximal tubule epithelial cells and its application to drug discovery and development

○Etsushi Takahashi¹, Kaoru Morimura¹, Ayano Araki¹, Fumihiko Kitagawa¹, Masayuki Kondo¹, Asami Saito², Gaku Morinaga², Masahito Takatani², Naoki Ishiguro², Hiroshi Arakawa³, Daichi Higuchi³, Ikumi Tamai³, Yoichi Jimbo¹ (1. NIKKISO CO., LTD., 2. Nippon Boehringer Ingelheim Co., Ltd, 3. Faculty of Pharmaceutical Sciences, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University)

[27P2-pm1-041] Effect of vildagliptin on mouse renal interstitial fibrosis

○Shigeyoshi Honma¹, Sota Kakuage¹, Yuta Morita¹, Makoto Yoshida¹ (1. Fac. Pharmacy, Takasaki University of Health and Welfare)

[27P2-pm1-042] Effects of drinking water administration of indoxyl sulfate, a urea toxin, on vascular endothelial function in normal rats

○keisuke nakagawa¹, Narumi Toda¹, Shuhei Kobuchi², Masashi Tawa¹, Mamoru Ohkita¹ (1. Dept. Pathol. & Mol. Pharmacol, Fac. Pharm, Osaka Med. & Pharmaceut. Univ., 2. Div. Pharmacol., Fac. Pharm., Hyogo Med. Univ.)

[27P2-pm1-043S] Involvement of endoplasmic reticulum stress in cisplatin-induced muscle atrophy of mouse

○Shinki Soga¹, Hayato Nanri¹, Yu Miyauchi¹, Yoshihiko Chiba¹, Risako Kon¹, Nobutomo Ikarashi¹, Tomoo Hosoe¹, Hiroyasu Sakai¹ (1. Hoshi Univ.)

[27P2-pm1-044S] Cell death responses induced by a potential anti-cancer agent MO2455 in lymphoma U937 cells

○ANKITHA VADI VELU¹, Barkha Saraswat¹, Ying Tong¹, Aung Bhone Myat¹, Kenji Matsuno², Takeji Takamura³, Fumiaki Koizumi¹, Mitsuko Masutani¹ (1. Dept. Molecular and Genomic Biomedicine & CBMM, Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Dept. Pharmacy, Yasuda Woman's Univ., 3. Fac. Engineering, Kanagawa Inst. Tech.)

[27P2-pm1-045S] Effect of cisplatin on changing in the gene expression of collagen and elastin in skin of mouse

○Miho Kiyama¹, Yu Miyauchi¹, Fumiaki Sato¹, Risako Kon¹, Nobutomo Ikarashi¹, Yoshihiko Chiba¹, Tomoo Hosoe¹, Hiroyasu Sakai¹ (1. Hoshi Univ.)

[27P2-pm1-046S] Platinum-based anticancer drugs-induced downregulation of myosin heavy chain isoforms in skeletal muscle of mouse

○Yu Miyauchi¹, Xinran Xu¹, Ken Sato¹, Yoshihiko Chiba¹, Risako Kon¹, Nobutomo Ikarashi¹, Junzo Kamei², Tomoo Hosoe¹, Hiroyasu Sakai¹ (1. Hoshi Univ., 2. Juntendo Univ.)

[27P2-pm1-047] Effect of cisplatin on gene expression of PGC-1α isoforms in murine skeletal muscle and C2C12 myotubes

○Hiroyasu Sakai¹, Satoshi Yoshida¹, Yu Miyauchi¹, Ken Sato¹, Fumiaki Sato¹, Risako Kon¹, Nobutomo Ikarashi¹, Yoshihiko Chiba¹, Junzo Kamei², Tomoo Hosoe¹ (1. Hoshi Univ., 2. Juntendo Univ.)

[27P2-pm1-048] Involvement of Caspases and MAP kinase in 2-methylthio dihydropyrimidine-triggered cytotoxicity against human leukemia NB4 cells

○Hidetomo Kikuchi¹, Yuki Toguchi¹, Yoshio Nishimura², Bo Yuan¹, Rie Arai³, Hidetsura Cho⁴, Katsuyoshi Sunaga¹ (1. Grad. Sch. Pharmaceut. Sci., Josai Univ., 2. Fac. Pharm., Ohu Univ., 3. Kyorin Univ. Sch. Med., 4. Grad. Sch. Pharmaceut. Sci., Tohoku Univ.)

[27P2-pm1-049S] Differentiation inducing effect of ATRA in combination with 2-methylthio dihydropyrimidine on human leukemia NB4 cells

○Yuki Toguchi¹, Hidetomo Kikuchi¹, Yoshio Nishimura², Bo Yuan¹, Rie Arai³, Hidetsura Cho⁴, Sunaga Katsuyoshi¹ (1. Grad. Sch. Pharmaceut. Sci., Josai Univ., 2. Fac. Pharm., Ohu Univ., 3. Kyorin Univ. Sch. Med., 4. Grad. Sch. Phamaceut. Sci., Tohoku Univ.)

[27P2-pm1-050S] Suppressive effects of KTtp compounds, novel pimozide derivatives, on T-type Ca²⁺ channel-dependent pruritus in mice

○Shiori Kino¹, Shotaro Kurahashi¹, Tomoya Ashida¹, Emiri Mishima¹, Iyo Nishiyama¹, Rina Minamino¹, Hiroyuki Nishikawa^1,2, Maho Tsubota¹, Fumiko Sekiguchi¹, Takuya Okada³, Naoki Toyooka³, Atsufumi Kawabata¹ (1. Fac. Pharm., Kindai Univ., 2. Fuso Pharmaceutical Industries, Ltd., 3. Fac Eng, Univ Toyama.)

[27P2-pm1-051] Sulfide-induced facilitation of Ca_v3.2 T-type Ca²⁺ channel-dependent pain sensitivity, and its inhibition by Ge-132, an organic germanium, via trapping sulfur

○Fumiko Sekiguchi¹, Hiroshi Masuda¹, Yoshihito Kasanami¹, Nene Koike¹, Nango Yuki¹, Yasuhiro Shimada², Kaho Sugimoto¹, Katsuyuki Sato², Takashi Nakamura², Hiroaki Yamaguchi³, Genzoh Tanabe¹, Shinsuke Marumoto⁴, Maho Tsubota¹, Atsufumi Kawabata¹ (1. Fac. Pharm., Kindai Univ., 2. Asai Germanium Res. Ins. Co. Ltd., 3. Grad. Sch. Med. Sci., Yamagata Univ., 4. Joint Res. Cent, Kindai Univ.)

[27P2-pm1-052S] Effect of Porphyromonas gingivalis, a highly pathogenic causative bacteria of periodontal disease, on inflammatory pathogenesis in normal or COPD airway.

○Noriki Takahashi^1,2, Toru Kariu³, Megumi Hayashi¹, Tomoki Kishimoto¹, Choyo Ogasawara¹, Ayami Fukuyama¹, Keisuke Kawano¹, Mary Ann Suico¹, Hirofumi Kai¹, Tsuyoshi Shuto¹ (1. Dept. Mol. Med., Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. Prog. Lead. Grad. Sch."HIGO", Grad. Sch. Pharm. Sci., Kumamoto Univ., 3. Dept. Life Sci., Shokei Univ.)

[27P2-pm1-053] Effects of dasatinib on airway inflammation in mice co-exposure of tobacco smoke and papain

○GENKI KIMURA¹, Daiki Ando¹, Kosuke Irie¹, Ikumi Kainuma¹, Yuki Katayama¹, Shiori Sato¹, Tomohiro Suzuki¹, Mai Harada¹, Tsubasa Yoshida¹, Yuki Nishimoto¹, Yasuo Kizawa¹ (1. Sch. Pharm. Nihon Univ.)

[27P2-pm1-054] Role of Nrf2 antioxidative system on 5-fluorouracil-induced myelosuppression

○Takashi Ashino¹, Kanata Akaike¹, Risako Chiba¹, Masayuki Yamamoto², Satoshi Numazawa¹ (1. Showa Univ. Sch. Pharm., 2. Tohoku Univ. Grad. Sch. Med.)

[27P2-pm1-055] Enhanced cytotoxicity of vitamin K₃ by TEMPOL, spin probe

○Shoko Okazaki¹, Mai Kaieda¹, Maiko Noshita¹, Yuiho Kuwahara¹, Motoki Terayama¹, Yuhei Ohta¹, Keizo Takeshita¹ (1. Fac. of Pharm. Sci. Sojo Univ.)

[27P2-pm1-056] Effect of the cigarette smoke extract derived from heated tobacco products on brain endothelial cells and pericytes

○Shinya Dohgu¹, Shota Kanbe¹, Fuyuko Takata¹, Takuro Iwao¹, Junichi Matsumoto¹, Miho Yasunaga¹, Miki Yokoya¹, Takahiro Horinouchi² (1. Fac. Pharmaceut. Sci., Fukuoka Univ., 2. Grad.Sch.Med., Hokkaido Univ.)

Session information

[27P2-pm1] Pharmacology 8