[IS03] PSJ/CSPS Joint Symposium "Molecular and Preclinical imaging and the Pharmaceutical Sciences"

Tue. Mar 28, 2023 2:00 PM - 4:50 PM [Room G2] Conference Hall (1F)

Organizer: Tomoya Uehara, Noriko Daneshtalab, Michael Doschak, Yoshinobu Takakura

Molecular imaging technique is a technology that captures various biological phenomena occurring in vivo at the molecular level and visualizes them in a living organism. Such techniques include X-ray CT, MRI, fluorescence imaging, nuclear medicine imaging (PET, SPECT) and so on, and imaging is performed using one or more of these. Such molecular imaging techniques is a very useful tool not only for diagnosis pathological conditions and elucidate biological phenomena, but also for drug development. For example, if a drug is labeled by a radionuclide, nuclear medicine imaging can be used to evaluate the kinetics of the drug. The efficacy of drugs can be evaluated by morphological evaluation using X-ray CT or MRI, and functional evaluation using nuclear medicine imaging and fluorescence imaging. Furthermore, it is also possible to obtain various information related to PK/PD, such as optimization of drug dosage and administration route. In this symposium, four speakers introduce the new attractions and applications of molecular or preclinical imaging in the pharmaceutical sciences.

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Opening remark: Tomoya Uehara (Grad. Sch. Pharm. Sci., Chiba Univ.) (2:00 PM - 2:05 PM)

2:05 PM - 2:30 PM

[IS03-01] Development of imaging probes for cancers and infectious diseases and their prospective in theranostics agents

○Takeshi Fuchigami¹, Kazuma Ogawa^1,2 (1. Grad. Sch. Med. Sci., Kanazawa Univ., 2. InFiniti., Kanazawa Univ.)

2:30 PM - 2:55 PM

[IS03-02] Using imaging techniques and functional studies to understand mechanisms of hemorrhagic stroke development and treatment options

○Noriko Daneshtalab¹ (1. Memorial University of Newfoundland)

2:55 PM - 3:20 PM

[IS03-03] Elucidation of pharmacokinetic factors affecting the efficacy of immune checkpoint inhibitors

○Hiroto Hatakeyama¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

3:20 PM - 3:45 PM

[IS03-04] Synthesis of bone-targeting peptide hormone analogues and in-vivo pharmacodynamic evaluation using micro-computed tomography

○Michael Doschak¹ (1. The University of Alberta)

Closing Remark: Noriko Daneshtalab (Memorial University of Newfoundland) (3:45 PM - 3:50 PM)

Break (3:50 PM - 4:00 PM)

4:00 PM - 4:50 PM

[IS03-P] Poster Session

Poster Session