[28P1-am2-046S] Effects of synthetic intrinsically disordered polypeptides on components including Stm1 in droplets in saccharomyces cerevisiae

○Mika Sakanashi¹, Shinya Takazaki¹, Kaho Sasaki¹, Toshimitsu Nakakura¹, Kazuhisa Ota¹ (1. Fac. of Pharm. Sci., Nagasaki Itn. Univ.)

[28P1-am2-047S] Involvement of Stm1 protein in stress granules and processing bodies in saccharomyces cerevisiae

○Kaho Sasaki¹, Shinya Takazaki¹, Mika Sakanashi¹, Toshimitsu Nakakura¹ (1. Fac. of Pharm. Sci., Nagasaki Itn. Univ.)

[28P1-am2-048S] Inhibitory effect on excitation-induced mitochondrial depolarization by KCC2 inhibitor VU0463271.

○Kana Omatsu¹, Mika Hirashima¹, Yuria Hara¹, Toshihiko Kinjo¹, Kyosuke Uno¹, Nobuyuki Kuramoto¹ (1. Setsunan University)

[28P1-am2-049] The subcellular distribution of lysosomal membrane glycoprotein LAMP-2 isoforms with tyrosine motifs that interact differentially with four adapter protein complexes

○Kenji Akasaki¹, Fumiaki Yamaguchi¹, Hiroshi Sakane¹ (1. Fac. Pharm. Sci., Fukuyama Univ.)

[28P1-am2-050] Functional analysis of cholesterol transporter NPC1L1 using SSD mutants.

○Jun Kamishikiryou¹, Akiho Shima¹ (1. Dept. Biochem. Fac. Pharm. Pharmaceut. Sci., Fukuyama Univ.)

[28P1-am2-051S] Skeletal muscle mitochondria-targeted DDS and activation of mitochondrial function

○Itsumi Sato^1,2, Yuma Yamada^1,3, Mitsue Hibino^1,4, Daisuke Sasaki^1,2, Atsuhito Takeda², Hideyoshi Harashima¹ (1. Grad. Sch. Pharm. Hokkaido Univ., 2. Grad. Sch. Med. Hokkaido Univ., 3. JST・FOREST, 4. Faculty. Engineering. Hokkaido Univ.)

[28P1-am2-052] Possible interaction of leptin receptor and IRE1α, an endplasmic reticulum stress sensor protein.

○Yasuhiro Noda¹, Yuki Shibuya¹, Kiwamu Tanaka¹, Nanako Matsuo¹, Tadashi Nakagawa¹, Toru Hosoi¹ (1. Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University)

[28P1-am2-053S] The role of cGAS-STING pathway in neovascular age-related macular degeneration

○Miruto Tanaka¹, Hiroto Yasuda¹, Kota Aoshima¹, Shinsuke Nakamura¹, Masamitsu Shimazawa¹ (1. Gifu Pharm. Univ.)

[28P1-am2-054] Occurrence of ferroptosis based on gemcitabine-induced mitochondrial dysfunction

○Miu Okada¹, Haruna Kishida¹, Yuhei Shimizu¹, Mahiro Matuhashi¹, Sanae Hirayama¹, Koichi Sakurai¹ (1. Hokkaido University of Science)

[28P1-am2-055] Analysis of oxidative-stress sensor Bag-1 cysteine residue mutant mouse

○Hayato Irokawa¹, Atsushi Inose^1,3, Kouki Takeda¹, Tomohiro Kimura², Osamu Nakajima², Masato Sasaki¹, Ryoya Sekine¹, Shusuke Kuge¹ (1. Fac. Pharm. Sci., Tohoku Med. Pharm. Univ., 2. Fac. Med., Yamagata Univ., 3. Fac. Pharm. Sci., Nihon Pharm. Univ.)

[28P1-am2-056] The regulation of cell cycle by two long non-coding RNAs, OIP5-AS1 and ANROC

○Yojiro Kotake¹, Yoshinobu Tanigawa¹, Ryoka Tarumi¹, Takahiro Wakasaki^2,3 (1. Fac. Humanity-Ori Sci Eng., Kindai Univ., 2. Dep. Otorhinolaryngology, Grad. Sch. Med. Sci., Kyushu Univ., 3. Otorhinolaryngology, Red Cross Fuk. Hospi.)

[28P1-am2-057S] Long-term single-cell imaging of leukemia cell lines using microwells

○Ryuta Niikura¹, Shohei Yamamoto¹, Takumi Chinen¹, Hiroaki Suzuki², Daiju Kitagawa¹ (1. Grad. Sch. Pharm. Sci., Tokyo Univ., 2. Fac. Sci. Eng., Chuo Univ.)

[28P1-am2-058S] Mitosis-specific phosphorylation of Ephexin4

○Ryuji Yasutake¹, Ryuzaburo Yuki¹, Youhei Saito¹, Yuji Nakayama¹ (1. Kyoto Pharmaceutical University)

[28P1-am2-059S] Inhibition of cytokinesis by the TNK2 inhibitor XMD16-5

○Mayu Murata¹, Ryoko Ota¹, Ryuzaburo Yuki¹, Youhei Saito¹, Yuji Nakayama¹ (1. Kyoto Pharmaceutical University)

[28P1-am2-060S] Functional analysis of the cancer-associated mutations of the ribosome biogenesis factor WDR74

○Tomoyo Nagano¹, Yuya Hirooka¹, Keiichi Izumikawa¹, Masami Nagahama¹ (1. Meiji Pharmaceutical University)

[28P1-am2-061S] The effects of depletion of plasma membrane cholesterol by methyl-β-cyclodextrin on cell division

○Junna Tanaka¹, Tae Amano¹, Ryuzaburo Yuki¹, Youhei Saito¹, Yuji Nakayama¹ (1. Kyoto Pharm. Univ.)

[28P1-am2-062] Analysis of the mechanism of induction of G2/M phase cell cycle arrest by pyrazole analog NK-356

○Tomoki Takahashi¹, Shunsuke Takahashi¹, Takahisa Shinomiya¹, Yukitoshi Nagahara¹ (1. Dept. of Sci. and Eng. , Tokyo Denki Univ.)

[28P1-am2-063] The role of prolyl oligopeptidase in the growth of human retinoblastoma cells

○Ayari Yoshida¹, Kaede Kawaguchi¹, Yume Nishikawa¹, Satoshi Tanaka¹, Minoru Sakaguchi¹ (1. Osaka Medical and Pharmaceutical University )

[28P1-am2-064] Nuclear translocation of GAPDH through interaction with prolyl oligopeptidase in S phase of neuroblastoma cells

○Wakaba Domoto¹, Hina Ishiguro¹, Yuya Yamaguchi¹, Kaito Kon¹, Akane Sawada¹, Amano Yumi¹, Tanaka Satoshi¹, Sakaguchi Minoru¹ (1. Osaka Medical and Pharmaceutical University)

[28P1-am2-065S] Generation and Characterization of CRISPR/Cas9-mediated NVL2 Knockout Cells

○Yukina Iwakawa¹, Sotaro Miyao¹, Keiichi Izumikawa¹, Masami Nagahama¹ (1. Meiji Pharmaceutical Univ.)

[28P1-am2-066] The roles of hyaluronan metabolism in human epidermal keratinocytes

○Yuta Yoshino¹, Natsuki Genkawa¹, Mai Hirose¹, Chika Miyamoto¹, Satoshi Endo¹, Akira Ikari¹ (1. Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University)

[28P1-am2-067S] IRBIT plays a critical role for adipogenesis

○Hiromi Takamura¹, Koichi Hamada¹, Kanako Kusumi¹, Ryoto Iwamoto¹, Ryusei Ono¹, Ayano Ohashi¹, Yurika Ito¹, Yasuaki Goto¹, Hiroyuki Kojima¹, Akihiro Mizutani¹ (1. Showa Pharmaceutical University)

[28P1-am2-068S] CLN10 A58V mutant interferes with the ER-driven anti-aggregate activity

○Yuki Shiro¹, Syouichi Katayama², Tetsuo Yamazaki² (1. Grad. Sch. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Biomed. Sci., Tokushima Univ.)

[28P1-am2-069] CLN6ʼs C-terminal mutantsʼ evaluation of the anti-aggregate activity and protein stability as a cause of CLN6 disease

○Kana Watanabe¹, Yuki Shiro², Shouichi Katayama³, Tetsuo Yamazaki³ (1. Sch. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Pharm. Sci., Tokushima Univ., 3. Grad. Sch. Biomed. Sci., Tokushima Univ.)

[28P1-am2-070] Effects of probucol on rotenone-induced oxidative stress and α-synuclein expression

○Tsugumi Takeo¹, Masateru Miyake², Hideya Mizuno¹ (1. Sch.Pharm.Aci., Mukogawa Women's Univ., 2. Pharmacovigilance Dept., Otsuka Pharmaceutical CO., Ltd.)

[28P1-am2-071] Studies on the effects of excessive fructose intake on mitochondrial function

Hitomi Nonaka¹, Saori Ohmori¹, ○Mio Abe¹, Naohiro Iwata¹, Mutsumi Fukaya¹, Makiko Furuya¹, Shinya Kamiuchi¹, Yasuhide Hibino¹ (1. Fac. Pharm. & Phamceu. Sci., Josai Univ.)

[28P1-am2-072] Changes in mitoNEET expression and cell viability in brain nerve cells caused by high-concentration glucose and high-cholesterol

○Natsumi Fujita¹, Ayana Nakata¹, Mio Kurino¹, Tsugumi Takeo¹, Hideya Mizuno¹ (1. Grad.Sch.Pharm.Sci.,Mukogawa Woman’s Univ.)

[28P1-am2-073S] PTEN stabilizes the gnome in nucleus.

○RIKA KIDO¹, AYUMI GINDEN¹, KAREN AKAMO¹, TAKASHI KATO¹ (1. Faculty of Pharmacy.YASUDA Woman Univ.)

[28P1-am2-074S] Functional analysis of tyrosinase in human melanoma cells metastasis

○Sachie Honda¹, Masahiro Fujimuro¹, Yuichi Sekine¹ (1. Kyoto Pharm. Univ.)

[28P1-am2-075] Development of spheroids with adjustable drug sensitivity

○Kazuya Matsushima¹, Yoshihiko Watanabe^1,2, Nobuhiko Kojima^1,2 (1. Yokohama City University, Yokohama, Japan , 2. Ecocell Co., Ltd)

[28P1-am2-076S] The effects of methylmalonic acid on colorectal cancer cell spheroids

○Junna Yamamoto¹, Rizu Inokuchi¹, Chiho Murakami¹, Hideya Yamamoto¹, Arowu Tanaka¹ (1. Dept. of Pharm., Yasuda Woman’s Univ. )

[28P1-am2-077S] Identification of the amino acids responsible for the intracellular localization

○Karen Akamo¹, Ayumi Jinden¹, Rika Kido¹, Takashi Kato¹ (1. Yasuda Women’s Univ)

[28P1-am2-078] Post-translational modification of DYRK1A during mitotic phase

○Eishi Funakoshi¹, Kaho Yoshikawa¹ (1. Dept. Life. Sci. Setsunan Univ.)

Session information

[28P1-am2] Structures and functions of cells 2