Study on in vivo metabolism of antisense oligonucleotides modified with bridged nucleic acids using LC-MS/MS

○Takahiro Kikuchi

[26P2-pm2-117] Study on in vivo metabolism of antisense oligonucleotides modified with bridged nucleic acids using LC-MS/MS

○Takahiro Kikuchi¹, Satoshi Itou¹, Shun Kumagaya², Kosuke Chiba², Masaki Yamagami², Kenta Hashizume¹ (1. Drug Development Solutions Center, Sekisui Medical Co., Ltd., 2. Research and Development Division, Luxna Biotech Co., Ltd.)

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Presentation information

[26P2-pm2] Pharmaceutics

[26P2-pm2-117] Study on in vivo metabolism of antisense oligonucleotides modified with bridged nucleic acids using LC-MS/MS

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