<em>De novo</em> discovery of macrocyclic peptide inhibitors containing cyclic γ-amino acids targeting the SARS-CoV-2 main protease

○Takashi Miura

4:50 PM - 5:02 PM

[27E1-pm16S] De novo discovery of macrocyclic peptide inhibitors containing cyclic γ-amino acids targeting the SARS-CoV-2 main protease

○Takashi Miura¹, Tika Malla², David Owen^3,4, Anthony Tumber², Lennart Brewitz², Michael McDonough², Eidarus Salah², Naohiro Terasaka¹, Takayuki Katoh¹, Petra Lukacik^3,4, Claire Strain-Damerell^3,4, Halina Mikolajek^3,4, Martin Walsh^3,4, Akane Kawamura^2,5, Christopher Schofield², Hiroaki Suga¹ (1. Grad. Sch. Sci., Univ. of Tokyo, 2. Univ. of Oxford, 3. Diamond Light Source, 4. Research Complex at Harwell, 5. Newcastle Univ.)

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Presentation information

[27E1-pm] Biosynthesis

[27E1-pm16S] De novo discovery of macrocyclic peptide inhibitors containing cyclic γ-amino acids targeting the SARS-CoV-2 main protease

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