[28HS2-am] ADME, PK/PD

[28HS2-am01S] Effects of cell passage number on the functional property of human immortalized cell-based blood-brain barrier models: a part of the qualification study

○Seiya Ohki¹, Tomoyo Baba¹, Hanae Morio¹, Shingo Ito², Sumio Ohtsuki², Ryo Ito³, Yoshiyuki Yamaura⁴, Takafumi Komori⁵, Tomomi Furihata¹ (1. Lab Clin Pharm & Exp Therapeut, Sch Pharm, Tokyo Univ Pharm & Life Sci., 2. Dpt Pharmaceu Microbiol, Faculty Life Sci, Kumamoto Univ., 3. Res Ctr Neurol, Ono Pharmaceutical Co., Ltd., 4. Pharmacokinet Res Lab, Ono Pharmaceutical Co., Ltd., 5. Global Drug Metab & Pharmacokinet, Tsukuba Res Lab, Eisai Co. Ltd.)