[3P-274] Accumulation of undegraded autophagosomes by expression of Syntaxin17 dominant negative mutants

^○Uematsu Masaaki¹, Nishimura Taki¹, Sakamaki Yuriko², Mizushima Noboru¹ (1.Dept. of Biochem. and Mol. Biol., Grad. School and Faculty of Med., The Univ. of Tokyo, 2.Research Center for Med. and Dent. Sci., Tokyo Med. and Dent. Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-275] (2T09p-11)Live-imaging analysis of a novel organelle degradation system in the lens using mice and zebrafish.

^○Morishita Hideaki, Mizushima Noboru (Dept. of Biochem & Mol. Biol., Faculty of Med., Univ. of Tokyo)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-276] Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy

^○Ishimura Ryosuke^1,2,3, Tanaka Keiji², Komatsu Masaaki³ (1.Dep. of Biochem., Sch. of Med., Niigata Univ., 2.Lab. of Pro. Meta., Tokyo Metro. Inst. of Med. Sci., 3.Fro.Sci., Univ. of Tokyo)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-277] (2T09p-12)An isolation membrane precursor forms in close apposition to phosphatidylinositol synthase-enriched membranes

^○Nishimura Taki¹, Tamura Norito², Koyama-Honda Ikuko¹, Mizushima Noboru¹ (1.Dept. of Biochem & Mol. Biol., Faculty of Med., The Univ. of Tokyo, 2.Dept. of Physiol. & Cell Biol., Tokyo Med. & Dent. Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-278] (2T09p-13)Functional analysis of PI(4)P in selective autophagy

^○Iwamoto Ryo¹, Hasegawa Junya¹, Yoshimori Tamotsu^1,2 (1.Lab. of Intracellular Membrane Dynamics, Grad. School of Frontier Biosciences, Osaka Univ., 2.Dept. of Genetics, Grad. School of Medicine, Osaka University)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-279] The peroxin Pex14p is the key component for coordinating autophagic degradation of mammalian peroxisomes by directly binding to LC3-II

^○Jiang Li¹, Kuge Sayuri², Yamashita Shun-ichi³, Fujiki Yukio² (1.Grad. Sch. of Life Sci., Kyushu Univ., 2.Department of Biology, Faculty of Sciences, Kyushu University Graduate School, 3.Laboratory of Biosignaling, Niigata University Graduate School of Medical and Dental Sciences)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-280] Upregulation of Rab7 during geranylgeranoic acid-induced autophagy

^○Okamoto Kyoko, Sakimoto Yoko, Shidoji Yoshihiyo (Div. of Nutr. Sci., Grad. Sch. of Human Health Sci., Univ. of Nagasaki)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-281] (2T09p-14)Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7

^○Yamaguchi Masaya¹, Matoba Kazuki², Sawada Ryoko¹, Fujioka Yuko², Nakatogawa Hitoshi³, Yamamoto Hayashi³, Kobashigawa Yoshihiro¹, Hoshida Hisashi⁴, Akada Rinji⁴, Ohsumi Yoshinori³, Noda Nobuo², Inagaki Fuyuhiko¹ (1.Fac. of Advanced Life Science, Hokkaido Univ.,, 2.Institute of Microbial Chemistry, 3.Integrated Research Institute, Tokyo Institute of Technology, 4.Department of Applied Molecular Bioscience, Yamaguchi University Graduate School of Medicine)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-282] Role of mitSMase in mitochondrial dysfunction-induced cell death

^○Kumagai Takeshi, Nishimura Naoe, Hata Yoko, Toyama Eri, Abe Nozomi, Nakagawa Yasuhito, Imai Hirotaka (Sch.of Pharm.Sci., Kitasato Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-283] Activation mechanisms of ASK1 by SARM, a mitochondria-localized TIR domain-containing adaptor molecule

^○Sekine Shiori, Hatanaka Wakako, Ichijo Hidenori (Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM