[3P-314] Protein tyrosine phosphatase PTP-ε membrane-type isoform is induced by FcεRI-crosslinking and mediates activation signals in mast cells lipid rafts

^○Koizumi Karen, Honda Reika, Aoki Kaori, Motohashi Satoru, Palmer Helen, Mashima Keisuke (Dep.of Life Science,Rikkyo(St.Paul's)Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-315] Targeted disruption of the mouse protein phosphatase PPM1L gene leads to structural abnormalities in the brain.

^○Kobayashi Takayasu¹, Fujita Kousuke¹, Shinoda Yasuharu¹, Nagaura Yuko¹, Kusano Rie¹, Watanabe Toshio², Matsui Yasuhisa³, Funahashi Jun-ichi¹, Sato Tatsuya⁴, Sakagami Hiroyuki⁵, Ohnishi Motoko⁶, Tamura Shinri¹ (1.Dept. of Project Program, IDAC, Tohoku Univ., 2.Dept. of Biol., Grad. Sch. of Humanities and Sciences, Nara Women's Univ., 3.Cell Resource Center for Biomed. Res., IDAC, Tohoku Univ., 4.CID, Tohoku Univ., 5.Dept. of Internal Medicine and Cardiology, Kitasato Univ. Sch. of Med., 6.College of Biosci. and Biotech., Chubu Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-316] Method for analysis of intracellular phosphorylation signaling by Multi-PK antibody and Phos-tag

^○Sugiyama Yasunori¹, Morisawa Keiko², Higuchi Takuma², Todaka Hiroshi², Yamaguchi Fumika², Ando Noriko², Sakamoto Shuji² (1.Dept. Appl. Biol. Sci., Fac. Agr., Kagawa Univ., 2.Lab. of Mol. Biol., Sci. Res. Cent., Kochi Med. Sch., Kochi Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-317] (3T14p-10)Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma

^○Makinoshima Hideki¹, Takita Masahiro^1,2, Matsumoto Shingo¹, Yagishita Atsushi¹, Owada Satoshi³, Esumi Hiroyasu³, Tsuchihara Katsuya^1,2 (1.Div. of TR, EPOC, Natl. Cancer Ctr., 2.Dep. Int. Biosci., Grad. School, The Univ. of Tokyo, 3.Res. Insti. Bio. Sci., The Tokyo Univ. of Sci.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-318] Phosphorylation of EGFR at serine 1047 by stimulation of TLR5 in cultured lung epithelial cells

^○Yamamoto Hideyuki¹, Noguchi Nobuhiro², Maeda Noriko¹, Nakamine Sayomi¹, Kondo Yutaka³, Toku Seikichi¹ (1.Dept. of Biochem., Grad. Sch. of Med., Univ. of Ryukyus, 2.Dept. of Anest., Grad. Sch. of Med., Univ. of Ryukyus, 3.Dept. of Emergency Med., Grad. Sch. of Med., Univ. of Ryukyus)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-319] (3T14p-13)Regulation of the RhoG-specific guanine nucleotide exchange factor SGEF by tyrosine phosphorylation

^○Okuyama Yusuke¹, Harada Kohei², Negishi Manabu^1,2, Katoh Hironori^1,2 (1.Lab. of Mol Neurobiol., Grad. Sch. of Pharm., Kyoto Univ., 2.Lab. of Mol Neurobiol., Grad. Sch. of Biostudies., Kyoto Univ.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-320] Novel activation mechanism of small G protein Arf6 in clathrin-dependent endocytosis; Activation of Arf6 mediated by GEF and Dynamin.

^○Okada Risa¹, Hasegawa Hiroshi², Kanaho Yasunori¹ (1.Dept. Phisiol. Chem., Grad. Comprehensive human sciences, Univ. of Tsukuba, 2.Fac. of Med., Univ. of Tsukuba)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-321] (3T14p-15)Fingerprinting of GPCR activity across multiple G protein substrates reveals complex profiles of functional selectivity

^○Masuho Ikuo, Kramer Grant, Jones Christopher, Martemyanov Kirill (Dept. of Neuroscience, Scripps FL)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM

[3P-322] (3T14p-14)PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway

^○Sato Katsuya^1,2, Suzuki Takahiro³, Yamaguchi Yoshihiro⁴, Kitade Yukio^1,3, Nagase Takahiro⁴, Ueda Hiroshi^1,3 (1.Uni. Grad. Sch. of Drug Disc. and Med. Info. Sci., Gifu Univ., 2.Dept. Molecul. Pathobiochem., Gifu Univ., 3.Dept. of Biomol. Sci. Fac. Eng., Gifu Univ., 4.Kazusa DNA Res. Inst.)

第87回日本生化学会大会 |Fri. Oct 17, 2014 3:00 PM - 4:00 PM

[3P-323] Regulation of proliferation by DKK1

^○Kimura Hirokazu, Fumoto Katsumi, Kikuchi Akira (Dept. Mol. Biol. and Biochem., Grad. Sch. Med., Osaka Univ)

第87回日本生化学会大会 |Fri. Oct 17, 2014 2:00 PM - 3:00 PM