[2P-391] (2T15a-01)Generation of snail knockout cell by CRISPR/Cas9 system and the investigation of alteration in the cellular metabolism

^○Haraguchi Misako, Ozawa Masayuki (Dept. of Biochem& Mol.Biol., Grad.sch.of Med. & Dent. sci., Kagoshima Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-392] Difference in localization of preneoplastic lesions, CD34-positive hepatocytes and phospholipase A2 group IVc-positive cells during peroxisome proliferator-induced rat hepatocarcinogenesis

^○Shimizu Takeshi¹, Nanashima Naoki², Yamada Toshiyuki¹, Tsuchida Shigeki¹ (1.Dept. Biochem. Genome Biol., Hirosaki Univ. Grad. Sch. Med., 2.Dept. Biomed. Sci., Hirosaki Univ. Grad. Sch. Health Sci.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-393] Roles of extracellular vesicles in the pancreatic ductal cancer microenvironment

^○Chiba Mitsuru¹, Sakai Ayaka³, Kubota Shiori³, Sato Konomi³, Kawamura Chihiro³, Monzen Satoru^1,2, Nanashima Naoki^1,2, Nakamura Toshiya^1,2 (1.Div. Life Sci., Hirosaki Univ. Grad. Sch. Health Sci., 2.Res. Center for Biomed. Sci., Hirosaki Univ. Grad. Sch. Health Sci., 3.Dep. Med. Tech., Hirosaki Univ. Sch. Health Sci.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-394] Effects of p53 tetramerization domain mutants found in Li-Fraumeni syndrome on hetero-oligomerization and transcriptional activity

^○Kanno Madoka¹, Imagawa Toshiaki^1,2, Toguchi Yu¹, Kamada Rui^1,2, Sakaguchi Kazuyasu^1,2 (1.Lab. of Biol. Chem., Grad. Sch. of Chem. Sci. & Eng., Hokkaido Univ., 2.Lab. of Biol. Chem., Dept. of Chem., Fac. of Sci., Hokkaido Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-395] (2T15a-06)Lysophosphatidic acid in malignant X-ray stimulates motillity of human pancreatic cancer cells.

^○Komachi Mayumi¹, Takahashi Akihisa², Noda Shin-ei¹, Okamoto Masahiko³, Murata Kazutoshi⁴, Suzuki Yoshiyuki¹, Nakano Takashi¹ (1.Dep. of Radiation Oncol, of Med, Gunma Univ., 2.Adv. Scientific Research Leaders Development Unit, Gunma Univ., 3.Gunma Univ. Heavy Ion Medical Center, 4.Dep. of Radiology and Radiation Oncol,. Gunma Univ Hospital.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-396] Effects of a highly selective MMP-2 inhibitor on tumor cell invasion and angiogenesis

^○Sano Mina, Higashi Shouichi (Grad. Sch. Nanobiosci., Yokohama city Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-397] Analysis of resistance to anti-cancer drugs and post-translational protein modification of Ras in refractory cancer cells

^○Imai Masahiko, Ozawa Tsubasa, Takahashi Noriko (Lab. of Physiolog. Chem., Inst. of Med. Chem., Hoshi Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-398] Characterization of side-population cells in pancreatic cancer cells

^○Nakashima Katsuhiko, Sakai Ryuichi (Natl. Cancer Ctr. Res. Inst., Div. of Metastasis & Invasion Signaling)

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM

[2P-399] (2T15a-12)Identification of a cell surface protein that induces cancer cell aggregation after cleavage by MMP-7

^○Ishikawa Tomohiro¹, Kimura Yayoi², Hirano Hisashi², Higashi Shouichi¹ (1.Grad. Sch. Nanobiosci., Yokohama city Univ., 2.Grad. Sch. Lifesci. Adv. Med. Cent., Yokohama city Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 2:00 PM - 3:00 PM

[2P-400] (2T15a-07)Epigenetic regulation of FABP5 gene expression in human prostate cancer

^○Kawaguchi Koichiro¹, Kinameri Ayumi², Suzuki Shunsuke³, Fujii Hiroshi⁴ (1.Interdisciplinary Grad. Sch of Sci. and Tech., Shinshu Univ., 2.Dept. of Biosci. & Biotech., Shinshu Univ. Grad. Sch of Agr., 3.Div.of Epigenomics, Frontier Agriscience & Technology center, Shinshu Univ., 4.Dept. of Interdisciplinary Genome Sci. & Cell Met., Institute for Biomedical Sciences, Shinshu Univ. (IBSS), Interdisciplinary Cluster for Cutting Edge Research (ICCER))

第87回日本生化学会大会 |Thu. Oct 16, 2014 3:00 PM - 4:00 PM