[2T09a-14] (3P-076)LC-MS/MS determination of human plasma 1-palmitoyl-2-hydroperoxyoctadecadienoyl phosphatidylcholine isomers

^○Kato Shunji¹, Ito Jyunya¹, Mizuochi Shunsuke¹, Nakagawa Kiyotaka¹, Asai Akira², Oikawa Shinichi², Nagashima Kazuyuki³, Miyazawa Teruo^1,4 (1.Food and Biodynamic Chem. Lab., Grad. Sch. Of Agri. Sci., Tohoku Univ., 2.Div. of Endocrinol., Dept. of Med., Nippon Med. Sch., 3.The Cardiovasc. Inst., 4.New Industry Creation Hatchery Center (NICHe), Tohoku Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 10:44 AM - 10:52 AM

[2T09a-15] (3P-075)Activation of inflammatory stress response by saturated phospholipids

^○Kurihara Daisuke¹, Kono Nozomu¹, Arai Hiroyuki^1,2 (1.GRAD. SCH. OF PHARM. SCI., The Univ. of. Tokyo, 2.CREST JST)

第87回日本生化学会大会 |Thu. Oct 16, 2014 10:52 AM - 11:00 AM

[2T09p-01] (2P-261)Polysulfides derived from H₂S, are possible signaling molecules that activate TRPA1 channels in rat brain

^○Kimura Yuka¹, Mikami Yoshinori², Osumi Kimiko¹, Tsugane Mamiko³, Oka Jun-ichiro⁴, Hideo Kimura¹ (1.Dept. of Mol. Pharmacol., National Inst. Neuroscience, NCNP, 2.Dept. Pharmacol., Grad. Sch. Med., Univ. of Tokyo, Tokyo, Japan, 3.Fcalty. Sci. Eng., Chuo Univ., Tokyo, Japan, 4.Dept. Pharmacy, Tokyo Univ. of Sci., Chiba, Japan)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:15 PM - 4:23 PM

[2T09p-02] (2P-262)Study of orexin-A and -B discrimination by orexin receptors

^○Suga Hinako^1,2, Yanagisawa Masashi¹ (1.Mol. Core, Univ. Tsukuba, 2.IIS, Univ. Tokyo)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:23 PM - 4:31 PM

[2T09p-03] (2P-263)Acidic pH inhibits interleukin-1β production by down-regulation of MAPK activity through the TDAG8/PKA pathway in mouse microglia

^○Sato Koichi, Jin Ye, Tobo Ayaka, Mogi Chihiro, Okajima Fumikazu (Lab. of Signal Transduction, IMCR, Gunma Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:31 PM - 4:39 PM

[2T09p-04] (2P-268)Development of agonists for LysoPS receptor -Approach from LysoPS analogs-

^○Uwamizu Akiharu¹, Inoue Asuka^1,2, Ikubo Masaya³, Nakamura Sho³, Jung Sejin³, Sayama Misa³, Kishi Takayuki¹, Makide Kumiko^1,2, Aoki Junken^1,4 (1.Lab. of Mol. Cell. Biochem., Grad. Sch. of Pharm. Sci., Tohoku Univ., 2.PRESTO, JST, 3.Lab. of Org. Med. Chem., Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 4.CREST, JST)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:39 PM - 4:47 PM

[2T09p-05] (2P-273)Establishment of LysoPS receptor mutant Jurkat T cellby CRISPR-Cas9-mediated genome engineering

^○Shinjo Yuji¹, Inoue Asuka^1,2, Ishiguro Jun¹, Makide Kumiko^1,2, Aoki Junken^1,3 (1.Laboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 2.PRESTO, JST, 3.CREST, JST)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:47 PM - 4:55 PM

[2T09p-06] (2P-272)GGIP: structure and sequence-based GPCR-GPCR interaction pair predictor

^○Nemoto Wataru¹, Yamanishi Yoshihiro², Limviphuvadh Vachiranee³, Toh Hiroyuki⁴ (1.Div. of Life. Sci. and Eng., Tokyo Denki Univ, 2.MiB., Kyshu Univ, 3.BII., A*Star., Singapore, 4.CBRC., AIST)

第87回日本生化学会大会 |Thu. Oct 16, 2014 4:55 PM - 5:03 PM

[2T09p-07] (2P-280)The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis

^○Sato Akira¹, Kayama Hisako², Shojima Kensaku¹, Matsumoto Shinji¹, koyama Hirofumi¹, Minami Yasuhiro³, Nojima Satoshi⁴, Morii Eiichi⁴, Honda Hiroaki⁵, Takeda Kiyoshi², Kikuchi Akira¹ (1.Dept. Mol. Biol. and Biochem., Grad. Sch. Med., Osaka Univ., 2.Dept. Micro. Immunol., Grad. Sch. Med., Osaka Univ., 3.Dept. Physiol. and Cell Biol., Grad. Sch. Med., Kobe Univ., 4.Dept. Pathol., Grad. Sch. Med., Osaka Univ., 5.Dept. Disease Model, Res. Inst. Radiation Biol. and Med., Hiroshima Univ.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 5:03 PM - 5:11 PM

[2T09p-08] (2P-284)Ligand recognition mechanisms of receptors for neutrophil-activating mitocryptides

^○Nakashima Kenta, Marutani Takayuki, Hattori Tatsuya, Aoki Shinichiro, Umeda Ryuhei, Nimoto Yoshiaki, Noguchi Kosuke, Fukui Akane, Yamanaka Yosuke, Kiso Yoshiaki, Mukai Hidehito (Lab. of Pept. Sci., Nagahama Inst. of Bio-Sci. & Tech.)

第87回日本生化学会大会 |Thu. Oct 16, 2014 5:11 PM - 5:19 PM