[4P-513] (4T15a-16)NCYM, a de novo gene evolved from MYCN antisense genes, encodes a protein regulating MYCN functions in human neuroblastomas

^○Suenaga Yusuke^1,2, Shoji Wataru^2,7, Rafiqul Islam², Jennifer Alagu², Yoshiki Kaneko², Mamoru Kato³, Yukichi Tanaka⁴, Hidetada Kawana⁵, Shamim Hossain¹, Makiko Itami⁵, Tatsuhiro Shibata³, Yohko Nakamura², Miki Ohira⁶, Seiki Haraguchi², Sana Yokoi¹, Akira Nakagawara^2,8 (1.Cancer Genome Ctr., Chiba Cancer Ctr. Res. Inst., 2.Div. Biochem. & Innov. Cancer Therap.,Chiba Cancer Ctr. Res. Inst., 3.Div. Cancer Genomics, Natl. Cancer Ctr. Res. Inst., 4.Dept. of Path., Kanagawa Children's Medical Ctr., 5.Div. Clin. Path., Chiba Cancer Ctr., 6.Div. Cancer Genomics, Chiba Cancer Ctr. Res. Inst., 7.Dept. of Pediatric Surgery, Grad. Sch. of Med., Tohoku Univ., 8.Saga Med. Ctr. Koseikan)

第87回日本生化学会大会 |Sat. Oct 18, 2014 1:20 PM - 2:20 PM

[4P-514] (4P-514)In vivo anti-tumor activity of antagomiR-224 in hepatocellular carcinoma

Sho Ri¹,^○Xuhong Zhang², Naoki Fukuda³, Hisayoshi Watanabe⁴, Takafumi Saito⁴, Michihiko Sato⁵, Tsunekata Ito³, Akira Fukao¹ (1.Dept. of Pub Health., Grad. Sch. of Med. Sci., Univ. of Yamagata, 2.Dept. of Biochem. & Mol. Bio., Grad. Sch. of Med. Sci., Univ. of Yamagata, 3.Lab. Animal Center, Inst. for Promotion of Med. Sci. Res., Fac. of Med., Univ. of Yamagata, 4.Dept. of Gastroenter. Fac. of Med., Univ. of Yamagata, 5.Central Lab. for Res. and Edu., Fac. of Med., Univ. of Yamagata)

第87回日本生化学会大会 |Sat. Oct 18, 2014 2:20 PM - 3:20 PM

[4P-515] (4T15a-17 )RNA Polymerase III Regulates Cytosolic RNA:DNA Hybrids and Intracellular MicroRNA Expression

^○Ishii Ken^1,2, Christine Koo^1,2,3, Stephan Gasser³ (1.National Institute of Biomedical Innovation (NIBIO), 2.Lab. Vaccine Science, WPI Immunolgy Frontier Rsearch Center (IFREC), Osaka University, 3.National University of Singapore (NUS))

第87回日本生化学会大会 |Sat. Oct 18, 2014 1:20 PM - 2:20 PM

[4P-516] (4T08p-12)Functional analysis of sex difference in mRNA and miRNA expression profiles in the spleen of infant mouse

^○Umezawa Masakazu^1,3, Ken Tachibana^1,2,3, Saki Okamoto³, Ken Takeda^1,3 (1.Cent. Env. Health Sci. Next Gen., RIST, Tokyo Univ. of Sci., 2.Nihon Pharm. Univ., 3.Dep. Hygiene Chem., Fac. Pharm. Sci., Tokyo Univ. of Sci.)

第87回日本生化学会大会 |Sat. Oct 18, 2014 2:20 PM - 3:20 PM

[4P-517] (4T15a-18 )MiRNA expression patterns and ROS production properties of Tumor-associated neutrophils

^○You Ren-In¹, Ho CL², Dai MS², Yen SF¹, Chen CS¹, Chao TY^2,3 (1.Dep. of La. Med. and Biotech., Tzu Chi Univ., 2.Division of Hematology/Oncology, Department of Medicine, Tri-Service General Hospital. National Defense Medical Center, Taipei, Taiwan., 3.Department of Internal Medicine, Taipei Medical University-Shuang-Ho Hospital, Taipei, Taiwan.)

第87回日本生化学会大会 |Sat. Oct 18, 2014 1:20 PM - 2:20 PM

[4P-518] (4T15p-16)Functional analysis of IBABP that is a target gene for nuclear receptor FXR in colorectal cancer cells.

^○Suzuki Hisatsugu¹, Yuki Kawamura¹, Hiroshi Fujii^1,2 (1.Dept. of Biosci. & Biotech.,Grad. Sch., Shinshu Univ., 2.Dept. of Interdisciplinary Genome Sci. & Cell Met., Inst. for Biomed. Sci. (IBS), Interdisci. Cluster for Cutting Edge Res. (ICCER), Shinshu Univ.)

第87回日本生化学会大会 |Sat. Oct 18, 2014 2:20 PM - 3:20 PM

[4P-519] (4P-519)Effect of Cys 60 of L-PGDS, egg-white allergen, on up-regulation of serum OVA-IgE level.

^○Suzuki Makiko¹, Shiho Nakanishi¹, Ryosuke Morimoto², Hiromi Yamashita² (1.Dept. of Nutrition, Fac. of Nutrition, Univ. of Kochi, 2.Dept. Nutritional Sci. Okayama Pref. Univ)

第87回日本生化学会大会 |Sat. Oct 18, 2014 1:20 PM - 2:20 PM

[4P-520] (4P-520)The Role of Osteocalcin in Early Atherosclerosis Progression

^○Kondo Akihiko, Tomoyo Kawakubo-Yasukochi, Akiko Mizokami, Masato Hirata (Lab.of Mol.Cell.Biochem., Fac of Dent.Sci., Univ. of Kyushu)

第87回日本生化学会大会 |Sat. Oct 18, 2014 2:20 PM - 3:20 PM

[4P-521] (4P-521)The effect of Quinolinic Acid on erythrocyte production

^○Goto Keita¹, Akira Ise¹, Mayu Muto¹, Saori Sezaki¹, Asami Miyahara¹, Yu Matsumoto¹, Shiro Takei², Shin-ichi Fukuoka³, Ryuzo Sasaki⁴, Katsumi Shibata⁵, Tsukasa Suzuki¹, Ken-ichi Kobayashi¹, Yuji Yamamoto¹ (1.Dept. Appl. Biol. Chem. ,Tokyo Univ. of Agri., 2.Medical Photonics Res. Ctr. ,Hamamatsu Univ. School of Med., 3.School of Cultural Creative Studies, Aoyama Gakuin Univ., 4.Nagahama Inst. Bio-sci. Tech., 5.School of Human Cultures, Univ. of Shiga Pref.)

第87回日本生化学会大会 |Sat. Oct 18, 2014 1:20 PM - 2:20 PM

[4P-522] (4T08p-11)Receptor function of chimeras of mouse Toll-like receptor 4 and 5

^○Uozumi Naonori, Takayuki Murakoshi (Dept. Biochem., Fac. Med., Saitama Medical Univ.)

第87回日本生化学会大会 |Sat. Oct 18, 2014 2:20 PM - 3:20 PM