[2P-322] Action mechanism of memory impairment by intake of calcium carbonate

^○Misa Kitamura, Ami Sugiura, Tatsurou Inoue, Yasushi Hasegawa (Muroran Institute of Technology)

The 92nd Annual Meeting of JBS

[2P-323] Sema4D deficiency-induced changes in arginine metabolism promote microglial proliferation in MCAO mice

^○Toshinori Sawano¹, Ryo Tsuchihashi², Natsumi Yamaguchi¹, Jin Nakatani¹, Shinobu Inagaki², Hidekazu Tanaka¹ (1.Laboratory of Pharmacology, Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, 2.Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University)

The 92nd Annual Meeting of JBS

[2P-324] Galectin 3 binding protein suppresses Aβ production via modulation of endogenous β-secretase activity

^○Tsuneyoshi Seki¹, Motoi Kanagawa¹, Kazuhiro Kobayashi¹, Hisatomo Kowa², Naoki Yahata^3,6, Kei Maruyama⁴, Nobuhisa Iwata⁵, Haruhisa Inoue^6,7,8, Tatsushi Toda^1,9 (1.Division of Neurology/Molecular Brain Science, Kobe University Graduate School of Medicine, 2.Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, 3.Department of Anatomy I, Fujita Health University School of Medicine, 4.Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 5.Department of Genome- based Drug Discovery, Graduate School of Biomedical Sciences, Nagasaki University, 6.Center for iPS Cell Research and Application (CiRA), 7.iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center (BRC), 8.Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), 9.Department of Neurology, Graduate School of Medicine, The University of Tokyo)

The 92nd Annual Meeting of JBS

[2P-325] The regulatory mechanism of ApoE expression via SphK2/S1P signaling

^○Masato Komai, Yuka Noda, Takashi Uehara, Nobumasa Takasugi (Dept. Medicinal Pharmacol., Grad. Sch. Med. Den. Pharmaceutical sci, Okayama Univ.)

The 92nd Annual Meeting of JBS

[2P-326] the regulation of Amyloid β degradation by GPR120

^○Kazunori Kikuchi, Kiwami Kidana, Yukiko Hori, Taisuke Tomita (Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 92nd Annual Meeting of JBS

[2P-327] MITOL prevents AD pathology by increasing Aβ oligomer aggregation

^○Mikihiro Mitsubori, Hiroko Iwasaki, Keisuke Takeda, Ryoko Inatome, Shigeru Yanagi (Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences)

The 92nd Annual Meeting of JBS

[2P-328] Autophagy controls intracellular/extracellular Aβ levels via exosome secretion

^○Nobuyuki Kimura¹, Shingo Koinuma¹, Nobuhiro Shimozawa², Yasuhiro Yasutomi² (1.Section of Cell Biology and Pathology, Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 2.Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition)

The 92nd Annual Meeting of JBS

[2P-329] Neural activity-dependent variation in the level of phosphorylated tau and its accumulation

^○Sosuke Yagishita¹, Shoko Hashimoto², Takashi Saito², Takaomi C. Saido², Toshiyuki Araki¹ (1.Dept. of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 2.Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science)

The 92nd Annual Meeting of JBS

[2P-330] Copy number variants in silver nanoparticles-primed hyperactive rats

^○Masami Ishido (nies)

The 92nd Annual Meeting of JBS

[2P-331] Characterization of liquid-liquid phase separation and cytotoxicity of C9orf72-encoding arginine-rich dipeptides.

^○Kohsuke Kanekura¹, Chen Chen², Yuhei Hayamizu², Masahiko Kuroda¹ (1.Department of Molecular Pathology, Tokyo Medical University, 2.Department of Materials Science and Engineering, Tokyo Institute of Technology)

The 92nd Annual Meeting of JBS