[2P-332] Molecular biological analysis of non-genetically modified Alzheimer's disease model; Octodon degus.

^○Nan Yagishita-Kyo¹, Chiharu Mitsuzawa², Haya Kosugiyama², Tomoko Uekita³, Kei Maruyama¹, Yuki Ikai⁴, Akio Shinohara⁴, Chihiro Koshimoto⁴, Sosuke Yagishita^1,5 (1.Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 2.Faculty of Health and Medical Care, Saitama Medical University, 3.Department of Psychology, Kyoto Tachibana University, 4.Division of Bio-Resources, Department of Biotechnology, Frontier Science Research Center, University of Miyazaki, 5.Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry)

The 92nd Annual Meeting of JBS

[2P-333] Oxidized vitamin C-modified protein regulates macrophage function

^○Masanori Itakura¹, Lumi Negishi², Miho Chikazawa¹, Eita Sasaki¹, Koji Uchida^1,3 (1.Laboratory of Food Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.Central Laboratory, Institute for Quantitative Biosciences, The University of Tokyo, 3.AMED-CREST)

The 92nd Annual Meeting of JBS

[2P-334] Hematopoietic regulation of Toll like receptor 4 signaling pathway

^○Yumi Sasaki¹, Yong-mei Guo², Tatsufumi Goto¹, Ken Asanuma³, Isuzu Kobayashi², Kumi Ubukawa², Naoto Takahashi², Hideki Wakui¹ (1.Department of Life Science, Graduate School of Engineering Science, Akita University, 2.Department of Hematology, Nephrology, & Rheumatology, Graduate School of Medicine, Akita University, 3.BERSC, Akita University)

The 92nd Annual Meeting of JBS

[2P-335] Uncovering the mechanism of epigenetic modification by T cell receptor signaling in regulatory T cells

^○Tomohide Kinoshita¹, Akira Nakajima¹, Norihito Hayatsu², Reiko Onishi², Shohei Hori¹ (1.Laboratory of Immunology and Microbiology Graduate School of Pharmaceutical Sciences, University of Tokyo, 2.Laboratory for Immune Homeostasis, Center for Integrative Medical Sciences (IMS-RCAI), RIKEN Yokohama Institute)

The 92nd Annual Meeting of JBS

[2P-336] A role of the transcription factor GATA1 for the establishment of regulatory T cell epigenome

^○Aya. Matsui¹, Saya. Shimizu², Shotaro. Funatsu², Eiryo. Kawakami³, Akira Nakajima¹, Shohei. Hori¹ (1.Grad Sch Pharm Sci, Univ Tokyo, 2.RIKEN IMS, 3.RIKEN MIH)

The 92nd Annual Meeting of JBS

[2P-337] Variable gene repertoirome analysis of peripheral blood BCRs and TCRs for qualitative evaluation of cancer-associated immune response.

^○Makoto Tsuiji, Sakiko Okabe, Harumi Shibusawa, Miyu Hayashi (Laboratory of Microbiology, Hoshi University School of Pharmacy and Pharmaceutical Sciences)

The 92nd Annual Meeting of JBS

[2P-338] Role of Endoplasmic Reticulum proteins Bap31 and CLIMP-63 in maintaining the Legionella pneumophila replicative niche

^○Hana Kimura^1,2, Yu Yanai², Mitsuo Tagaya², Mukherjee Shaeri¹, Kohei Arasaki² (1.University of California San Francisco, San Francisco, 2.Tokyo University of Pharmacy and Life Sciences)

The 92nd Annual Meeting of JBS

[2P-339] Functional analysis of pyrrolated proteins

^○Miho Chikazawa¹, Shiori Iwata¹, Masanori Itakura¹, Eita Sasaki¹, Koji Uchida^1,2 (1.Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.AMED-CREST)

The 92nd Annual Meeting of JBS

[2P-340] Dissecting the mechanism by which a novel IPS-1 binding protein induces antiviral responses

^○Saeko Aoyama-Ishiwatari, Tomohiko Okazaki, Yukiko Gotoh (Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 92nd Annual Meeting of JBS

[2P-341] Impaired antigen-specific lymphocyte priming after Toll-like receptor 4 activation via induction of monocytic myeloid-derived suppressor cells

^○Hiroki Tsukamoto, Sao Kozakai, Yohei Kobayashi, Risako Takanashi, Takuya Aoyagi, Yoshihisa Tomioka (Laboratory of Oncology, Pharmacy Practice and Sciences, Graduate School of Pharmaceutical Sciences, Tohoku University)

The 92nd Annual Meeting of JBS