[3P-030] Establishment of NPC1-knockout cells from various human cell lines and their lipidomic analysis of major lipids

^○Takeru Suzuki^1,2, Shota Sakai¹, Yoshitaka Shirasago¹, Saho Suzuki^1,3, Tetsuyuki Kobayashi³, Kentaro Hanada¹, Masayoshi Fukasawa¹ (1.Dept. Biochem. & Cell Biol., Natl. Inst. Infect. Dis., 2.Dept. Biol. Sci. & Tech., Tokyo Univ. of Sci., 3.Graduate School of Humanities and Sciences, Ochanomizu University)

The 92nd Annual Meeting of JBS

[3P-031] Role of lysophosphatidic acid receptor LPA₃ in food intake

^○Yukitaka Sato¹, Kuniyuki Kano^1,2, Mayu Kanno¹, Junken Aoki^1,2 (1.Lab. of Mol. Cell. Biochem. , Grad. sch. of Pharm. Sci., Tohoku Univ., 2.AMED-LEAP)

The 92nd Annual Meeting of JBS

[3P-032] The depletion of polyunsaturated fatty acid (PUFA) in phospholipid causes membrane blebbing due to breaking cortical actin

^○Yuri Saito¹, Yuki Ishino¹, Kojiro Mukai², Shinichi Araki³, Tomohiko Taguchi², Hiroyuki Arai⁴ (1.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo,, 2.Department of Organelle Disease, Graduate School of Life Sciences, Tohoku University,, 3.Department of Histology and cell biology, Graduate school of Medicine Kagawa University, 4.Division of Medical environment engineering, Center of Life Science and Engineering, Graduate school of Medicine, The University of Tokyo,)

The 92nd Annual Meeting of JBS

[3P-033] Dominant mutations of PSS1 impairs osteoclast multi-nucleation - a model of Lenz-Majewski syndrome -

^○Sari Sugahara¹, Yuta Shimanaka¹, Hiroyuki Arai^1,2, Nozomu Kono¹ (1.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan, 2.Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan)

The 92nd Annual Meeting of JBS

[3P-034] The in vivo roles of long-chain acyl-CoA synthetase 4.

^○Hiroshi Kuwata, Tsubasa Ochiai, Shuntaro Hara (School of Pharmacy, Showa University)

The 92nd Annual Meeting of JBS

[3P-035] Searching inhibitors of phospholipid transport and synthesis

^○Hiroya Shiino¹, Michiko Hashimoto², Toshiya Endo³, Yasushi Tamura² (1.Graduate School of Science and Engineering, Yamagata University, 2.Faculty of Science, Yamagata University, 3.Faculty of Life Science, Kyoto Sangyo University)

The 92nd Annual Meeting of JBS

[3P-036] Augmentation of mitochondrial respiration by phospholipase A1 in pancreatic cancer cells.The relationship with Warburg effect.

^○Takanori Koizumi, Yuri Zenkou, Yuichi Suzuki, Chihiro Nozima, Naoki Matsumoto, Yasuhiro Hayashi, Yoko Nemoto-Sasaki, Takayuki Sugiura, Atsushi Yamashita (Faculty of Pharma-Sciences, Teikyo University)

The 92nd Annual Meeting of JBS

[3P-037] The function of saturated phosphatidylcholine in macrophage

^○Yusuke Ohki¹, Yuta Shimanaka¹, Nozomu Kono^1,2, Hiroyuki Arai³ (1.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.AMED, 3.Faculty of Medicine, The University of Tokyo Center for Disease Biology and Integrative Medicine, Clinical Biotechnology)

The 92nd Annual Meeting of JBS

[3P-038] The role of lysophosphatidylcholine acyltransferase 1 in the retina.

^○Katsuyuki Nagata^1,2, Daisuke Hishikawa¹, Hideo Shindou^1,3,4, Takehiko Yokomizo², Takao Shimizu¹ (1.Department of Lipid Signaling, National Center for Global Health and Medicine, 2.Department of Biochemistry, Juntendo University Graduate School of Medicine, 3.Department of Lipid Science, Graduate School of Medicine, The University of Tokyo, 4.AMED-CREST)

The 92nd Annual Meeting of JBS

[3P-039] Effect of cyclin-dependent kinase in the regulation of an enzyme activity of intracellular phospholipase A1 by phosphorylation.

^○Naoki Matsumoto, Yasuhiro Hayashi, Yoko Nemoto-Sasaki, Takanori Koizumi, Yukino Enta, Kenta Suzuki, Nae Takimoto, Yuki Hamano, Ayaka Takahashi, Atsushi Yamashita (Department of Biological Chemistry, Faculty of Pharma-Science, Teikyo University)

The 92nd Annual Meeting of JBS