[1T09a-05] Metagenomic and metabolomic analyses reveal dynamic shifts in gut microbiota along the adenoma-carcinoma sequence in colorectal cancer

^○Sayaka Mizutani^1,2, Shinichi Yachida^3,4, Hirotsugu Shiroma¹, Satoshi Shiba⁴, Takuji Yamada^1,5 (1.School of Life Science and Technology, Tokyo Institute of Technology, 2.Research Fellow of Japan Society for the Promotion of Science, 3.Department of Cancer Genome Informatics, Graduate School of Medicine/Faculty of Medicine, Osaka University, 4.Division of Cancer Genomics, National Cancer Center Research Institute, 5.PRESTO)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 2:00 PM - 2:10 PM

[1T10a-01] O-GlcNAc glycan on Notch1 receptor responds to extracellular environment

^○Mitsutaka Ogawa¹, Kenntarou Yogi¹, Yuya Senoo², Kazutaka Ikeda², Hideyuki Takeuchi¹, Tetsuya Okajima¹ (1.Dept. of Molecular Biochemistry, Nagoya University School of Medicine, 2.Kazusa DNA Res)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:20 PM - 1:30 PM

[1T10a-02] Cross-talk between O-GlcNAcylation and sialic acid metabolism

^○Shinji Go, Junko Matsuda (Kawasaki medical school, Dep. Pathophysiology and Metabolism)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:30 PM - 1:40 PM

[1T10a-03] Regulation of BCR signaling by CD22 and its glycan cis-ligands

^○Chizuru Akatsu, Amin Alborzian-Deh-Sheikh, Takeshi Tsubata (Dept. of Immunology, Medical Research Institute, Tokyo Med. Dent. Univ.)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:40 PM - 1:50 PM

[1T10a-04] The impacts of pathogenic mycobacteria on sphingolipid metabolic pathways in human neutrophils

^○Hitoshi Nakayama^1,2, Tomomi Hotta², Kouta Nakamura³, Kazuhisa Iwabuchi^1,2 (1.Fac. of Health Care and Nurs, Juntendo Univ., 2.Inst. Env. and Gen, Fac. of Med, Juntendo Univ., 3.Dep. of Res, Fac. of Med, Juntendo Univ.)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:50 PM - 2:00 PM

[1T10a-05] Adaptive immunity induced by artificial glycosphingolipids

^○Tetsuya Okuda¹, Satoshi Hasaba², Kayoko Kidowaki², Mutsuhiro Date² (1.Bioproduction Res. Inst., AIST, 2.Diagnostics Res. Lab., FUJIFILM Wako Pure Chem. Corp.)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 2:00 PM - 2:10 PM

[1T10a-06] Glucocerebrosidases regulate metabolism of newly found brain sterol metabolite glycosylated sterols

^○Hisako Akiyama¹, Mitsuko Ide², Etsuro Nakanishi³, Norihito Uemura³, Yoshiki Yamaguchi⁴, Greimel Peter⁵, Hiroyuki Kamiguchi¹, Ryosuke Takahashi³, Yoshio Hirabayashi² (1.Laboratory for Neural Cell Dynamics, Center for Brain Science, RIKEN, 2.Cellular Informatics Laboratory, RIKEN, 3.Department of Neurology, Kyoto University Graduate School of Medicine, 4.Laboratory of Pharmaceutical Physical Chemistry, Tohoku Medical and Pharmaceutical University, 5.Laboratory for Cell Function Dynamics, Center for Brain Science, RIKEN)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 2:10 PM - 2:20 PM

[1T11a-01] Requirement of PI(4)P phosphatases in clathrin-mediated endocytosis

^○Masahiro Suwazono¹, Ayaka Kigata¹, Makoto Nagano¹, Junko Y Toshima^1,2, Jiro Toshima¹ (1.Department of Biological Science and Technology, Tokyo University of Science, 2.School of Health Sciences, Tokyo University of Technology)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:20 PM - 1:30 PM

[1T11a-02] Anionic phospholipids stimulate the Ca²⁺-dependent formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A₂ε

^○Hussain Zahir¹, Uyama Toru¹, Binte Mustafiz Smriti Sultana¹, Kawai Katsuhisa², Tsuboi Kazuhito³, Araki Nobukazu², Ueda Natsuo¹ (1.Department of Biochemistry, Kagawa University School of Medicine, 2.Department of Histology and Cell Biology, Kagawa University School of Medicine, 3.Department of Pharmacology, Kawasaki Medical School)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:30 PM - 1:40 PM

[1T11a-03] The role of the membrane protein Ice2 in phospholipid metabolism in yeast

^○Satoru Fujii¹, Non Miyata², Osamu Kuge² (1.Department of Chemistry, Graduate School of Science, Kyushu University, 2.Department of Chemistry, Faculty of Science, Kyushu University)

The 92nd Annual Meeting of JBS |Wed. Sep 18, 2019 1:40 PM - 1:50 PM