[2T13a-02(P-468)] Novel substrates of selective autophagy identified by the purification of p62 droplet

^○Yuki Fujimoto, Reo Kurusu, Hideaki Morishita, Masaaki Komatsu (Department of Physiology, Juntendo University School of Medicine)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:00 PM - 3:10 PM

[2T13a-03(P-473)] Molecular mechanism of mammalian ATG9 vesicle recruitment in selective autophagy

^○Yutaro Hama, Noboru Mizushima, Hayashi Yamamoto (Dept. of Biochem. and Mol. Biol., Grad. Sch. of Med., The Univ. of Tokyo)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:10 PM - 3:20 PM

[2T13a-04(P-479)] PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and lysophagy

^○Yukako Oe¹, Shin-ichiro Yoshimura², Yasuyoshi Kimura³, Kensuke Ikenaka³, Hideki Mochizuki³, Shuhei Nakamura^1,4,5, Tamotsu Yoshimori^1,4,6 (1.Department of Genetics, Graduate School of Medicine, Osaka University, 2.Department of Cell Biology, Graduate School of Medicine, Osaka University, 3.Department of Neurology, Graduate School of Medicine, Osaka University, 4.Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, 5.Institute for Advanced Co-Creation Studies, Osaka University, 6.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:20 PM - 3:30 PM

[2T13a-05(P-507)] Detection of mitochondrial stress by novel ratiometric fluorescent probe and comprehensive exploration of mitochondrial stress

^○Rie Uesugi^1,2, Akira Matsuura³, Eisuke Itakura³ (1.Department of Biology, Graduate School of Scienceand Engineering, Chiba University, 2.Course of Biomedical Sciences, Graduate School of Medicine, Gunma University, 3.Department of Biology, Graduate School of Science, Chiba University)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:30 PM - 3:40 PM

[2T13a-06(P-517)] Identification of a novel unsaturated fatty acid sensor NPR1 linking changes in ER membrane lipid composition and epigenomic regulation by fatty acids

^○Ayano Tanaka¹, Yuuka Kitamura¹, Saeko Sugawara², Yuki Uhara¹, Erika Tabata¹, Manami Hirono¹, Tsugumi Murano¹, Yukiko Muroga¹, Masashi Omura¹, Kimiko Takahashi¹, Yaeko Nakatani¹, Takumi Nishiuchi³, Kouji Hirota⁴, Seiichi Oyadomari⁵, Taiji Ito^1,4,6 (1.Faculty of Family and Consumer Sciences, Kamakura Women's University, 2.Faculty of Human Life, Jumonji University, 3.Advanced Science Research Center, Kanazawa University, 4.Graduate School of Science, Tokyo Metropolitan University, 5.Institute of Advanced Medical Sciences, Tokushima University, 6.National Hospital Organization Yokohama Medical Center)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:40 PM - 3:50 PM

[2T13a-07(P-516)] Novel regulatory mechanisms of the MDM2-p53 pathway in DNA damage response

^○Tatsuya Shimada, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 3:50 PM - 4:00 PM

[2T13a-08(P-483)] p300-mediated acetylation promotes MCL1 stabilization and tumorigenesis

^○Kouhei Shimizu¹, Min Gi^2,3, Shugo Suzuki², Fuminori Tokunaga¹, Hiroyuki Inuzuka⁴, Wenyi Wei⁴ (1.Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, 2.Department of Molecular Pathology, Graduate School of Medicine, Osaka City University, 3.Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka City University, 4.Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 4:00 PM - 4:10 PM

[2T13a-09(P-487)] BACH1 inhibits aging-related phenotypes by promoting ferroptosis and subsequent secretion of FGF21.

^○Hironari Nishizawa, Mitsuyo Matsumoto, Kazuhiko Igarashi (Departement of Biochemistry, Tohoku University Graduate School of Medicine)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 4:10 PM - 4:20 PM

[2T13a-10(P-492)] Involvement of the novel noncanonical functions of Caspase-3 in the induction of parthanatos

^○Shuhei Hamano, Midori Suzuki, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 4:20 PM - 4:30 PM

[2T13a-11(P-488)] INSIGs mediate the oxysterol-dependent activation of PERK/ATF4 axis causing cell death

^○Yuichi Watanabe^1,2, Takashi Sasaki¹, Shoko Miyoshi¹, Makoto Shimizu¹, Yoshio Yamauchi¹, Ryuichiro Sato¹ (1.Dept. of Appl. Biol. Chem., Grad. Sch. of Agric. and Life Sci., Univ. of Tokyo, 2.Div. of Biol. Chem., Dept. of Pharm. Sci., Sch. of Pharm., Showa Univ.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 4:30 PM - 4:40 PM