[3P-0093] Mutagenic events mediated by Tyrosyl-DNA phosphodiesterases at a ribonucleotide embedded into DNA.

○Ayuna Takeishi¹, Hiroyuki Kogashi¹, Mizuki Odagiri¹, Hiroyuki Sasanuma², Shunichi Takeda², Manabu Yasui³, Masamitsu Honma³, Kaoru Sugasawa⁴, Kiyoe Ura¹, Akira Sassa¹ (1.Dept. of Biol., Grad. Sch. Sci., Univ. of Chiba, 2.Grad. Sch. Med., Univ. of Kyoto, 3.Div. Genet. ＆ Mutagen., NIHS., 4.Biosignal Research Center, Univ. of Kobe)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0094] Suppression of TopBP1 expression impairs the DNA damage response and promotes the induction of apoptosis by chemotherapeutic agents

○Yuko Obayashi^1,2, Ryousuke Fujikane¹, Yuka Uechi^1,4, Shou Morita^1,3, Tetsurou Ikebe², Akimitsu Hiraki², Masumi Hidaka¹ (1.Dept. of Physiol. Sci.and Mol.Biol., 2.Dept. of Oral and Maxill. Sug., 3.Dept. of Oral Rehab., 4.Dept. of Oral Growth and Dev.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0095] A possible role of histone methyltransferase NSD2 in DNA double-strand break repair pathway choice at the active gene locus

○Haruka Kobayashi¹, Akari Tojo¹, Akira Sassa¹, Manabu Yasui², Masamitsu Honma², Kiyoe Ura¹ (1.Dept. of Biol., Grad. Sch. of Sci., Univ. of Chiba, 2.Divi. Genet. & Mutagen., Natl. Inst. Health Sci.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0096] The putative functional domain of the MHG1 protein plays an important role in stabilization of mtDNA in Neurospora crassa

○Ryouhei Yoshihara¹, Hayami Seike¹, Keisuke Ishimori¹, Mao Kiryu², Asagi Watanabe², Ayumu Hiroishi², Shin Hatakeyama¹, Shuuitsu Tanaka¹ (1.Grad. Sch. of Sci. & Eng., Saitama Univ, 2.Fac. of Sci., Saitama Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0097] Genome editing using CRISPR/Cas9 to introduce the mutations detected in malignant mesothelioma patients into TSCE5 cells and functional assays.

○Shinsei Fujino^1,2, Misato Kimura², Mai Imasaka², Masaki Ohmuraya², Yoshie Yoshikawa² (1.Dept. of Biosci., Grad. Sch. of Sci. Tec., Kwansei Gakuin Univ., 2.Dept. of genetics., Hyogo College Of Medicine)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0098] Tumor suppressor BAP1 impairs the function of B cells (in vitro analysis using BAP1 knockout-B blastoid cells)

○Misato Takagi Kimura¹, Akio Tada², Takashi Kijima², Masaki Ohmuraya¹, Yoshie Yoshikawa¹ (1.Dept. of genetics. Hyogo College Of Medicine, 2.Dept. of Respiratory Medicine. Hyogo College Of Medicine)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0099] DNA-unwinding dynamics of Escherichia coli UvrD lacking the C-terminal 40 amino acids

○Hiroaki Yokota¹ (1.Biophoton. Lab., Grad. Sch. New Photon. Indust.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0100] Withdrawn

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0101] Epistasis analysis of the FAN1 and SNM1A homologues in Neurospora crassa

○Kotaro Tsukada¹, Ryouhei Yoshihara¹, Shin Hatakeyama¹, Shuuitsu Tanaka¹ (1.Grad. Sch. of Sci. & Eng., Saitama Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0102] Analysis of Histone H3K4R Substitution mutant in Neurospora

○Kento Yanagisawa¹, Ryouhei Yoshihara¹, Shin Hatakeyama¹, Shuuitsu Tanaka¹ (1.Grad. Sch. of Sci. & Eng., Saitama Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan