[3P-0325] Suppression of cellular senescence by inducing mitophagy in senescent cells

○Yui Okido¹, Keisuke Ashiba¹, Takeru Yamazaki¹, Honomi Miyashita¹, Koki Mino¹, Haruka Nishimura¹, Kiyoshi Sato¹, Hiroyoshi Kawakami¹ (1.Dept. of Appl. Chem., Grad. Sch. of Environ. Sci., TMU)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0326] Different sites of superoxide metabolism by SODs divide cell fate in fibroblasts.

○Kenji Watanabe¹, Shuichi Shibuya¹, Takahiko Shimizu¹ (1.Aging Stress Response Research PT., NCGG.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0327] Fisetin promotes hair growth by augmenting TERT expression

○kinue Hirae¹, Mizuki Ogawa¹, Chisato Kubo¹, Norihisa Uehara², Yoshinori Katakura³ (1.Grad.Sch.Bioev.Sci., Kyushu Univ., 2.Fac. Dent.Sci., Kyushu Univ., 3.Fac. Agric., Kyushu Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0328] DOK7 gene therapy enhances NMJ innervation, motor function, and muscle strength in aged mice

○Takahiro Eguchi¹, Satoshi Sugita², Yoshihiko Minegishi², Akira Shimotoyodome², Noriyasu Ota², Noboru Ogiso³, Ryo Ueta¹, Yuji Yamanashi¹ (1.Dev. of Genetics, IMSUT, Univ. of Tokyo, 2.Biol. Sci. Res., Kao Corp., 3.Lab. of Exp.Animals, Natl. Ctr. Geriatr. Gerontol)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0329] mTOR pathway regulates cold adaptation and longevity in Caenorhabditis elegans

○Makoto Horikawa¹, Adam Antebi², Masaki Mizunuma¹ (1.Dept. Mol. Biotech., Grad. Sch. Integ. Sci. Life, Hiroshima Univ., 2.Max Planck inst., Biol. Aging.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0330] The change of steroidogenesis with aging in mouse adrenal gland

○Noriyuki Okudaira¹, Takao Susa¹, Miho Akimoto¹, Harumi Hisaki¹, Shigeki Nishimori¹, Masayoshi Iizuka², Tomoki Okazaki¹, Mimi Tamamori-Adachi¹ (1.Dept. of Biochem., Teikyo Univ. Sch. of Med., 2.Med. Educ. Ctr., Teikyo Univ. Sch. of Med.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0331] Analysis of the effect of dead Bifidobacterium longum on mitochondrial homeostasis in C. elegans

○Takaya Sugawara¹, Kazuichi Sakamoto¹ (1.Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0332] Mutant IDH1 triggers Oncogene-Induced Senescence in normoxia

○Takeshi Kamakura^1,2, Younghui Jin^1,2, Sakura Tamaki^1,2, Makoto Watanabe^2,3, Takeshi Okamoto⁴, Hiroyuki Yoshitomi^5,6, Junya Toguchida^1,2,6,7 (1.inFront, Kyoto univ., 2.CiRA, Kyoto univ., 3.Life Sci. Res. Cent., Shimadzu Corp., 4.Japanese Red Cross Otsu Hospital, 5.Dept. of Immun. and Cell Biol., Grad. Sch. of Med., Kyoto univ., 6.Dept of Orthop. Surg., Grad. Sch. of Med., Kyoto univ., 7.iACT, Kyoto unv. Hosp., Kyoto univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0333] CCN3 accelerates senescence in articular cartilage

○Miho Kuwahara^1,4, Sei Kondo¹, Shanqi Fu¹, Mitsuaki Ono², Takayuki Furumatsu³, Eiji Nakata³, Shogo Minagi⁴, Masaharu Takigawa⁵, Satoshi Kubota¹, Takako Hattori¹ (1.Dept. of Biochem. Mol. Dent., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 2.Dept. of Mol. Biol. and Biochem., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 3.Dept. of Orthop. Surg., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 4.Dept. of Occlusal and Oral Func. Rehabil., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 5.ARCOCS, Okayama U. Dent. Sch.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0334] NAMPT-mediated cellular NAD⁺ increasement expands motile activity and longevity in Drosophila.

○Kenichi Kanai¹, Shan Wei¹, Yasukazu Nakahata², Yasumasa Bessho¹ (1.Boil. Sci., NAIST, 2.Dept. of Med. Dent., Nagasaki Univ. )

The 43rd Annual Meeting of the Molecular Biology Society of Japan