[3P-673] The functional analysis of human mesenchymal stem cells for cancer gene therapy

^○Makoto Sukegawa^1,2,3, Yoshitaka Miyagawa¹, Seiji Kuroda¹, Motoko Yamamoto¹, Kumi Adachi¹, Nobuhiko Taniai², Hiroshi Yoshida³, Akihiro Umezawa⁴, Mashito Sakai¹, Takashi Okada⁵ (1.Dept. of Biochem., Mol. Biol., Nippon Medical School, 2.Dept. of Gastrointestinal Surg., Nippon Medical School Musashikosugi Hospital, 3.Dept. of Surg., Nippon Medical School, 4.Cent. for Regenerative Med., National Center for Child Health and Development Research Institute, 5.Div. of Mol. and Med. Genetics, Center for Gene and Cell Therapy, The Institute of Med. Sci., The Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-674] Anticancer drug bleomycin does not cause fibrosis under cytotoxic dominance in the lung
～Evaluation of anticancer drug using precision-cut lung slices, PCLS～

^○Yoko Miura, Satoshi Kanazawa (Dept. of Neu. Disorder Genet.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-675] Retroviral replicating vector-mediated suicide gene therapy for osteosarcoma

^○Ayane Kawabe^1,2, Hiroaki Fujino^1,2, Emiko Sonoda¹, Yuya Takeuchi^1,2, Toru Takarada³, Noriyuki Kasahara⁴, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-676] Suicide gene therapy by retroviral replicating vectors for canine malignancies

^○Emiko Sonoda¹, Hiroaki Fujino^1,2, Ayane Kawabe^1,2, Yuya Takeuchi^1,2, Toru Takarada³, Shunsuke Noguchi⁴, Noriyuki Kasahara⁵, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Lab. of Vet. Radio., Grad. Sch. of Vet. Sci., Osaka Metropolitan Univ., 5.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-677] Cenpc-cΔex2-4 promotes tumor development in DMBA/TPA skin carcinogenesis model

^○Yurika Tokunaga^1,2, Kazuhiro Okumura², Eriko Isogai², Masatoshi Hara³, Tatsuo Fukagawa³, Yuichi Wakabayashi² (1.Dept. of Mol. Biol. & Onc., Grad. Sch. of Med. ＆ Pharm. Sci., Univ. of Chiba, 2.Dept. of Ex. Anim. Res., CCCRI., 3.Grad. Sch. of Front. Biosci., Univ. of Osaka)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-678] ACA-28 and the derivative ACAGT-007a induce apoptosis by further activating ERK MAPK signaling in cancer cells

^○Ryosuke Sato, Golam Iftakhar Khandakar, Fumihiro Ishikawa, Teruaki Takasaki, Genzoh Tanabe, Reiko Sugiura (Fac. of Pharm., Kindai Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-679] The transcription factor DACH1 promotes tumor angiogenesis and tumor development

^○Tomohiro Hatatani¹, Aoi Fujioka², Ribon Matsumoto², Akira Fujisawa², Megumi Mukai¹, Haruko Hayasaka^1,2,3 (1.Dept. of Sci., Grad. Sch. Sci. Eng., Univ. of Kindai, 2.Dept. of Life Sci., Fac. Sci. Eng., Univ. of Kindai, 3.Res. Inst. of Sci. and Tech., Univ. of Kindai)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-680] Verification of SNPD-siPIK3CA targeting single nucleotide mutation in PIK3CA oncogene in breast cancer-derived cells

^○Toshinori Ohyama¹, Yoshiaki Kobayashi², Kumiko UiTei² (1.Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ of Tokyo, 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-681] Polyunsaturated fatty acids suppress the growth of pancreatic cancer cells via ferroptosis

^○Akane Suda¹, Yoshiteru Kagawa¹, Umaru Banlanjo Abdulaziz¹, Yuriko Saiki², Toru Furukawa², Yuji Owada¹ (1.Dept. of Organ Anatomy., Grad. Sch. of Med., Tohoku Univ., 2.Dept. of Investigative Pathology., Grad. Sch. of Med., Tohoku Univ.)

The 45th Annual Meeting of the Molecular Biology Society of Japan

[3P-682] Analysis of a molecular mechanism by HIF-1a in gefitinib-resistance acquisition in lung cancer

^○chisato iwabuchi^1,2, nobuyuki tanaka² (1.Department of Human Genetics, Research Institute, National Center for Global Health and Medicine, 2.Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School)

The 45th Annual Meeting of the Molecular Biology Society of Japan