[1P-0044] Whole transcriptome analysis of mitochondrial DNA somatic mutation detected in breast cancer patients

○Kenji Watanabe¹, Shigeru Yamamoto², Noriko Meda², Syuiti Sakaguti³, Mikako Yagi⁴, Dongchon Kang⁴, Masaaki Oka², Hiroaki Nagano², Yoichi Mizukami¹ (1.Center for Gene Res., Sci. Res. Center, Univ. of Yamaguchi, 2.Dept. of Digestive Surgery and Surgical Oncology, Grad. Sch. of Med., Univ. of Yamaguchi, 3.Ins. of RI Res., Sci. Res. Center, Univ. of Yamaguchi, 4.Dept. of Clinical Chem. and Lab. Med., Grad. Sch. of Med. Sci., Univ. of Kyushu)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0045] MoG+: a database to harness mouse genomic variation for experimental animal science

○Toyoyuki Takada¹, Tatsuya Kushida¹, Toshihiko Shiroishi², Hiroshi Masuya¹ (1.Integrated Bioresource Information Division, RIKEN BRC, 2.Office of the Center Director, RIKEN BRC)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0046] Deletion of Mir223 Exacerbates Lupus Nephritis by Targeting S1pr1 in Fas^lpr/lpr Mice

○Sumie Asano^1,2, Tomoyuki Mukai¹, Yoshitaka Morita¹, Jun Wada² (1.Department of Rheumatology Kawasaki Medical School　, 2.Department of Nephrology, Rheumatology, Endocrinology and Metabolism Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0047] Massively parallel dissection of regulatory elements driving neural induction

○Fumitaka Inoue^1,3, Anat Kreimer^1,2, Tal Ashuach², Nir Yosef², Nadav Ahituv¹ (1.Dept. Bioeng. Ther. Sci., UCSF, 2.Dept. Elect. Eng. Comp. Sci., UCB, 3.ASHBi, Kyoto Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0048] CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats

○Motoko Unoki¹, Jafar Sharif², Yuichiro Saito³, Hiroyuki Sasaki¹ (1.Div. of Epigenomics Dev., Med. Inst. of Bioreg., Kyushu Univ., 2.Lab. for Dev. Genet., RIKEN Cent. for Integ. Med. Sci., 3.Mol. Cell Engineering Lab., Nat. Inst. of Genet.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0049] NMR analysis for dynamic behavior of histone H3 N-tails invisible in the EM structure of nucleosomal complex with FACT

○Yasuo Tsunaka¹, Hideaki Ohtomo¹, Kosuke Morikawa², Yoshifumi Nishimura^1,3 (1.Grad. Sch. of Med. Life Sci., Yokohama City Univ., 2.Grad. Sch. of Biostudies, Kyoto Univ., 3.Grad. Sch. of Int. Sci. Life, Univ. of Hiroshima)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0050] Autism-related protein USP9X epigenetically regulates rDNA through SETD5

○Tadashi Nakagawa^1,2, Makiko Nakagawa¹, Toru Hosoi², Keiko Nakayama¹ (1.Div. of Cell Prolif., Grad. Sch. of Med., Tohoku Univ., 2.Dep. of Clin. Pharm., Faculty of Pharm. Sci., Sonyo-Onoda City Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0051] FABP7 regulates nuclear acetyl-CoA metabolism in astrocytes.

○Yoshiteru Kagawa¹, Banlanjo Abdulaziz Umaru¹, Yuji Owada¹ (1.Dept. of Organ Anatomy, Grad. Sch of Med. ,Univ. of Tohoku)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0052] Three methods to generate disease model mice by epigenome editing

○Takuro Horii¹, Sumiyo Morita¹, Shinjiro Hino², Mika Kimura¹, Yuko Hino², Hiroshi Kogo³, Mitsuyoshi Nakao², Izuho Hatada¹ (1.Biosignal Genome Resour. Ctr., IMCR, Gunma Univ., 2.Dept. of Med. Cell Biol., IMEG, Kumamoto Univ., 3.Dept. of Anatomy & Cell Biol., Grad. Sch. of Med., Gunma Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0053] Structural dynamics of heterochromatin protein HP1 studied by site-directed spin labeling ESR spectroscopyː Effects of DNA binding and phosphorylation

Toshiaki Arata^1,5, Kazunobu Sato⁴, リサ Mutoh⁶, Yuichi Mishima⁵, Ena Hirai⁴, Takeji Takui⁴, Toru Kawakami⁵, Hironobu Hojo⁵, Toshimichi Fujiwara⁵, Makoto Miyata¹, ○isao suetake^2,3,5 (1.Dept. Biol., Grad. Sch. Sci., Osaka City Univ., 2.Nakamura Gakuen Univ., 3.Twin Research Center, Osaka Univ., 4.English] Dept. Chem., Grad. Sch. Sci., Osaka City Univ., 5.IPR, Osaka Univ., 6.Dept. Phys., Fac. Sci.,Fukuoka Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan