[3AW-08-Discussion~Conclusion] Discussion~Conclusion

○Fuminori TOKUNAGA¹, ○Akira NAKAI ² (1.Osaka City University, 2.Yamaguchi University)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 11:05 AM - 11:15 AM

[3AW-11-Introduction] Introduction

○Daisuke KAIDA¹ (1.University of Toyama)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 9:00 AM - 9:05 AM

[3AW-11-1] Amending splice defects by small molecule compounds

○Masahiko Ajiro^1,2, Masatoshi Hagiwara² (1.Dept. of Drug Discovery Med., Grad. Sch. of Med., Kyoto Univ., 2.Dept. of Anat. and Dev. Biol., Grad. Sch. of Med., Kyoto Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 9:05 AM - 9:25 AM

[3AW-11-2] Effectiveness of transcriptome analysis in deciphering molecular pathology of patients with suspected genetic disorders

○Mamiko Yamada¹ (1.Center for Medical Genetics, Sch. of Med, Univ. of Keio)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 9:25 AM - 9:40 AM

[3AW-11-3] Analysis of the mechanism how CDK9 inhibitors modulate pre-mRNA splicing

○Hiroshi Maita¹ (1.Fac. of Pharm. Sci., Hokkaido Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 9:40 AM - 10:00 AM

[3AW-11-4] Comprehensive Analysis of Dicer Substrates by High-Throughput Sequencing Identified New Target RNA Motifs for Small Molecules

○Asako Murata¹, Yusuke Takashima¹, Kei Iida², Ayako Sugai¹, Masatoshi Hagiwara², Kazuhiko Nakatani¹ (1.ISIR, Osaka Univ., 2.Grad. Sch. of Med., Kyoto Univ. )

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 10:00 AM - 10:20 AM

[3AW-11-5] How does splicing inhibitor exert its potent anti-tumor activity?

○Daisuke Kaida¹ (1.Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 10:20 AM - 10:35 AM

[3AW-11-6] Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns

○Jagat K. Chhipi Shrestha^1,2, Tilman Schneider-Poetsch¹, Takehiro Suzuki³, Mari Mito⁴, Khalid Khan¹, Naoshi Dohmae³, Shintaro Iwasaki^4,5, Minoru Yoshida^1,2,6 (1.Chem. Gen. Res. Gr., RIKEN CSRS, 2.Dept. of Biotech., Grad. Sch. of Agr. and Life Sci., Univ. of Tokyo, 3.Biomol. Char. Unit, Tech. Platf. Div., RIKEN CSRS, 4.RNA Sys. Biochem. Lab., RIKEN CPR, 5.Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 6.Coll. Res. Ins. for Innovat. Microbio., Univ. of Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 10:35 AM - 10:55 AM

[3AW-11-7] Alternative splicing of PKM as a potential therapeutic target in cancer

○Nobuhiro Tanuma¹ (1.Div. Cancer Chemother., Miyagi Cancer Ctr. Res. Inst.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 10:55 AM - 11:15 AM

[3AW-12-1] A cellular modifier drives amyloid formation through charge complementation

Anita Pras¹, Bert Houben², Francesco Aprile³, Renee Seinstra¹, Rodrigo Gallardo², Leen Janssen¹, Wytse Hogewerf¹, Matthias De Vleeschouwer², Alejandro Mata-Cabana¹, Mandy Koopman¹, Esther Stroo¹, Minke De Vries¹, Samantha Edwards¹, Michele Vendruscolo³, Fabio Falsone⁴, Frederic Rousseau², Joost Schymkovitz², ○Ellen Nollen¹ (1.Dept. Biol. Ageing, Univ. of Groningen, 2.Dept. Cell. Mol. Med. Dept. KU Leuven, 3.CMD, Dept. of Chem., Univ. of Cambridge, 4.Inst. Pharm. Sc., Univ. of Graz)

The 43rd Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 4, 2020 9:00 AM - 9:25 AM