[PS14] Parallel Session 14: ASD / ADHD 2

[PS14-2B-K ] Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder: Neurological Perspective and Advances in Neuroscientific Research

^○Toyojiro MATSUISHI^{1, 2} (1.Research Center for Children, Research Center for Rett Syndrome, St. Mary’s Hospital, Japan, 2.Cognitive and Molecular Research Institute for Brain Diseases, Kurume University, Japan)

Thanks to recent advances in clinical and basic neuroscience, including neuroimaging, molecular biology, neurochemistry and neurotransmitter/neuromodulator study, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are now relatively well understood. However, the viewpoint from genetic and epigenetic roles remain unclear. Today, I would like to introduce our research group’s own original study investigating microamine, review ADHD and ASD research advances, then emphasize the importance of early intervention and treatment. I will also review the role of sleep problems in individuals with ADHD and ASD. Furthermore, Rett syndrome is key to clarifying the mechanism of ASD and other neurodevelopmental disorders. Therefore, I will also refer to our recent study of clinical and basic research using primary culture cells, that is, embryonic stem cells. Finally, I would like to introduce our ongoing project that proposes a new approach to future perspectives of ADHD and ASD, with a particular focus on rhythm disorder, which is associated with people with ASD.