Academic Program [Oral A]

17. Biofunctional Chemistry, Biotechnology » Oral A

[D1441-3am] 17. Biofunctional Chemistry, Biotechnology

Fri. Mar 24, 2023 9:00 AM - 11:30 AM D1441 (1441, Bldg. 14 [4F])

Chair: Kazuhito Tanabe, Yusuke Kitamura

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9:00 AM - 9:10 AM

[D1441-3am-01] Analyses of intracellular uptake pathways and dynamics of acyclic artificial nucleic acids SNA and L-aTNA

Yukiko Kamiya¹, ^○Kiyoka Sakashita¹, Hiroyuki Asanuma¹ (1. Nagoya University)

[Lang.] Japanese

9:10 AM - 9:20 AM

[D1441-3am-02] In vivo suppression of target gene expression by XNAs Staple based on RNA hacking technology

^○Tomoki Kida¹, Yousuke Katsuda¹, Takuto Kamura¹, Yuusuke Kitamura¹, Masaki Hagihara², Shin-ichi Sato³, Ihara Toshihiro¹ (1. Faculty of Advance Science and Technology, Kumamoto University, 2. Faculty of Science and Technology, Hirosaki University, 3. Institute for Chemical Research, Kyoto University)

[Lang.] Japanese

9:20 AM - 9:30 AM

[D1441-3am-03] Novel mechanism of gene expression control technology using RNA hacking

^○Yua Itsuki¹, Yousuke Katsuda¹, Yusuke Kitamura¹, Toshihiro Ihara¹ (1. Kumamoto Univ. )

[Lang.] Japanese

9:30 AM - 9:40 AM

[D1441-3am-04] Photo-oxidation in the vicinity of nucleic acid double helix (1) photo-oxidation property of guanine in DNA duplex by ¹O₂

^○Takashi Kanamori¹, Shota Kaneko¹, Hideya Yuasa¹ (1. Tokyo Institute of Technology)

[Lang.] Japanese

9:40 AM - 9:50 AM

[D1441-3am-05] Photooxidation in the vicinity of nucleic acid double helix (2) photo-oxidation property of guanine in RNA duplex by ¹O₂ and application to photo-antisense method

^○Shota Kaneko¹, Takashi Kanamori¹, Hideya Yuasa¹ (1. Tokyo Institute of Technology)

[Lang.] Japanese

Break (9:50 AM - 10:00 AM)

10:00 AM - 10:10 AM

[D1441-3am-06] Synthesis of base-modified nucleoside triphosphates containing 1,2-diol and their substrate properties in polymerase reactions

^○Rei Katou¹, Kouki Tajiri¹, Erika Nagatani¹, Hidekazu Hoshino², Yuuya Kasahara^2,3, Satoshi Obika^3,2,4, Hiroto Fujita¹, Masayasu Kuwahara¹ (1. Nihon University, 2. NIBIOHN, 3. Grad. Sch. Pharm. Sci., Osaka Univ., 4. OTRI, Osaka Univ.)

[Lang.] Japanese

10:10 AM - 10:20 AM

[D1441-3am-07] The examination of membrane permeability and translation activity of chemically modified mRNA

^○Satomi Sugiyama¹, Haruka Hiraoka¹, Yuko Nakashima¹, Naoko Abe¹, Zhenmin Li¹, Shunichi Kato¹, Yuki Yoshida¹, Mikiya Kase¹, Hiroshi Abe^1,2,3 (1. Nagoya University, 2. Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (JST CREST), 3. Institute for Glyco-core Research (iGCORE))

[Lang.] Japanese

10:20 AM - 10:30 AM

[D1441-3am-08] Analysis of G-quadruplex Binding Protein of EWS for Transcriptional Regulation of TERRA

^○Luthfi Lulul Ulum¹, Maiko Yamanashi², Haruka Morikawa², Takanori Oyoshi^1,2,3 (1. Graduate School of Science and Technology, Shizuoka University, 2. Graduate School of Integrated Science and Technology, Shizuoka University, 3. Research Institute of Green Science and Technology, Shizuoka University)

[Lang.] English

10:30 AM - 10:40 AM

[D1441-3am-09] Identification and performance evaluation of amplifier elements in isothermal nucleic acid amplification reactions

^○Chihiro Kubo¹, Hiroto Fujita¹, Masayasu Kuwahara¹ (1. Nihon university)

[Lang.] Japanese

Break (10:40 AM - 10:50 AM)

10:50 AM - 11:00 AM

[D1441-3am-10] Aggregates Formation between CUG Repeat RNA Sequences and MBNL1

^○Surachada Chuaychob¹, Wanqing Hou¹, Musashi Shimizu¹, Shun Nakano¹, Arivazhagan Rajendran¹, Eiji Nakata¹, Takashi Morii¹ (1. Institue of Advanced Energy, Kyoto University)

[Lang.] English

11:00 AM - 11:10 AM

[D1441-3am-11] Evaluation of the reactivity of TopoisomeraseⅠ to G-quadruplex DNA

^○Ryoma Yokosawa¹, Koya Sakamoto¹, Takanori Oyoshi^1,2,3 (1. Graduate school of Integrated Science and Technology , Shizuoka University, 2. Graduate School of Science and Technology, Shizuoka University, 3. Research Institute of Green Science and Technology, Shizuoka University)

[Lang.] Japanese

11:10 AM - 11:20 AM

[D1441-3am-12] Development of G4 binding protein regulating G4-containing promoter

^○Maiko Yamanashi¹, Yamato Karikome¹, Akinori Ishihara¹, Takanori oyoshi^1,2,3 (1. Graduate school of integrated Science and Technology, Shizuoka University, 2. Graduate school of Science and Technology, Shizuoka University, 3. Research Institute of Green Science and Technology, Shizuoka University)

[Lang.] Japanese

11:20 AM - 11:30 AM

[D1441-3am-13] Small molecules regulate liquid-liquid phase separation induced by G-quadruplex

^○Nagisa Takamiya¹, Mitsuki Tsuruta¹, Yoshiki Hashimoto¹, Keiko Kawauchi¹, Daisuke Miyoshi¹ (1. Konan University, FIRST)

[Lang.] Japanese

Session information

[D1441-3am] 17. Biofunctional Chemistry, Biotechnology

[D1441-3am-01] Analyses of intracellular uptake pathways and dynamics of acyclic artificial nucleic acids SNA and L-aTNA

[D1441-3am-02] In vivo suppression of target gene expression by XNAs Staple based on RNA hacking technology

[D1441-3am-03] Novel mechanism of gene expression control technology using RNA hacking

[D1441-3am-04] Photo-oxidation in the vicinity of nucleic acid double helix (1) photo-oxidation property of guanine in DNA duplex by ¹O₂

[D1441-3am-05] Photooxidation in the vicinity of nucleic acid double helix (2) photo-oxidation property of guanine in RNA duplex by ¹O₂ and application to photo-antisense method

[D1441-3am-06] Synthesis of base-modified nucleoside triphosphates containing 1,2-diol and their substrate properties in polymerase reactions

[D1441-3am-07] The examination of membrane permeability and translation activity of chemically modified mRNA

[D1441-3am-08] Analysis of G-quadruplex Binding Protein of EWS for Transcriptional Regulation of TERRA

[D1441-3am-09] Identification and performance evaluation of amplifier elements in isothermal nucleic acid amplification reactions

[D1441-3am-10] Aggregates Formation between CUG Repeat RNA Sequences and MBNL1

[D1441-3am-11] Evaluation of the reactivity of TopoisomeraseⅠ to G-quadruplex DNA

[D1441-3am-12] Development of G4 binding protein regulating G4-containing promoter

[D1441-3am-13] Small molecules regulate liquid-liquid phase separation induced by G-quadruplex

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