[E1661-1am] 17. Biofunctional Chemistry, Biotechnology

[E1661-1am-04] Development of PureCap Analogs for Co-transcriptional Capping Enable Synthesis of Fully Capped Messenger RNA

^○Masahito Inagaki¹, Naoko Abe¹, Zhenmin Li¹, Yuko Nakashima^1,2, Susit Acharyya¹, Kazuya Ogawa¹, Daisuke Kawaguchi¹, Haruka Hiraoka¹, Bannno Ayaka¹, Zheyu Meng¹, Mizuki Tada¹, Tatsuma Ishida¹, Pingxue Lyu¹, Kengo Kokubo¹, Hirotaka Murase¹, Fumitaka Hashiya², Yasuaki Kimura¹, Satoshi Uchida^4,3, Abe Hiroshi^1,5,6,2 (1. Nagoya University, 2. Research Center for Materials Science, Nagoya University, 3. Kyoto Prefectural University of Medicine, 4. iCONM, 5. JST-CREST, 6. iGCORE)

[Lang.] Japanese

Keywords:Cap Structures, PureCap Analogs, mRNA Therapeutics, Photo-Cleavable Hydrophobic Protecting Groups, In Vitro Transcription