Poster(17:30-19:30)

[P-127] Conversion of an agonistic anti-TNFR2 biparatopic antibody into an antagonist by structural modification

*Takuya Otsuki¹, Hiroki Akiba^1,2, Sigeyuki Matsumoto³, Ryo Kanada⁴, Junso Fujita^5,6, Keiichi Namba^5,6, Yasushi Okuno^3,4, Haruhiko Kamada^1,2, Hiroaki Ohno^1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NIBIOHN, 3. Grad. Sch. Med., Kyoto Univ., 4. RIKEN, 5. Grad. Sch. Front. Biosci., Osaka Univ., 6. JEOL YOKOGUSHI Res. Alliance Lab., Osaka Univ.)