[P-148] The Effects of Incorporating Acyclic Nucleic Acids on the Toxicity and Efficacy of Gapmer-ASOs *Jumpei Ariyoshi1, Ayaka Minamikawa1, Mioka Okuno1, Nozomi Tanigawa1, Aki Tsumura1, Yuuka Suzumura1, Tomoki Onabe2, Masaya Higuchi1, Hiroyuki Asanuma2, Yukiko Kamiya1,2 (1. Kobe Pharmaceutical University, 2. Graduate School of Engineering, Nagoya University) Abstract password authentication.Password is required to view the abstract. Please enter a password to authenticate. Password Authentication