*Yared Beyene Yohannes¹, Shouta MM NAKAYAMA¹, John Yabe², Haruya Toyomaki¹, Andrew Kataba², Kaampwe Muzandu², Hokuto Nakata¹, Yoshinori Ikenaka¹, Kennedy Kennedy Choongo², Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Hokkaido University, Japan, 2.School of Veterinary Medicine, University of Zambia, Zambia)

*Shouta MM NAKAYAMA^1,2, Yoshiya Yamamura^1,3, Satomi Kondo⁴, Chiyo Kitayama⁴, Takahiro Ichise¹, Yoshinori Ikenaka^1,5,6,7, Mayumi Ishizuka¹ (1.Faculty of Veterinary Medicine, Hokkaido University, 2.School of Veterinary Medicine, The University of Zambia, 3.The Institute of Environmental Toxicology, 4.Everlasting Nature of Asia (ELNA), 5.Water Research Group, School of Environmental Sciences and Development, North-West University, Private Bag X6001, Potchefstroom 2531, South Africa, 6.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan, 7.One Health Research Center, Hokkaido University, Sapporo 060-0818, Japan)

*Nyein Chan Soe^1,2, Takamitsu Ohigashi³, Hokuto Nakata¹, Chikae Tatsumi³, Yoshitaka Uchida⁴, Walubita Mufalo⁵, Mayumi Ito⁶, Tsutomu Sato⁶, Toshifumi Igarashi⁶, Yared B Yohannes^1,7, Yoshinori Ikenaka^1,8,9,10, Mayumi Ishizuka¹, Shouta MM NAKAYAMA^1,11 (1.Laboratory of Toxicology, Department of Environmental Veterinary Science, Faculty of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo, 060-0818, Japan, 2.Department of Pharmacology and Parasitology, University of Veterinary Science, Yezin, Nay Pyi Taw, 15013, Myanmar, 3.Graduate School of Global Food Resources, Hokkaido University, Sapporo, 060-8589, Japan, 4.Global Center for Food, Land and Water Resources, Research Faculty of Agriculture, Hokkaido University, Sapporo, 060- 8589, Japan, 5.Graduate School of Engineering, Hokkaido University, Sapporo, 060- 8628, Japan, 6.Faculty of Engineering, Hokkaido University, Sapporo, 060- 8628, Japan, 7.Department of Chemistry, College of Natural and Computational Science, University of Gondar, Ethiopia, 8.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan , 9.One Health Research Center, Hokkaido University, Japan, 10.Water Research Group, School of Environmental Sciences and Development, North-West University, South Africa, 11.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, P.O. Box 32379, Lusaka 10101, Zambia)

*Rio Doya¹, Shouta MM Nakayama^1,2, Hokuto Nakata¹, John Yabe^2,3, Kaampwe Muzandu², Yoshinori Ikenaka^1,4,5, Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Faculty of Veterinary Medicine, Hokkaido University , 2.School of Veterinary Medicine, The University of Zambia, 3.Faculty of Health Sciences and Veterinary Medicine, School of Veterinary Medicine, University of Namibia, 4.One Health Research Center, Hokkaido University, 5.Unit for Environmental Sciences and Management, North-West University)

*Mitsuki Kondo¹, Yoshinori Ikenaka^1,2,3,4, Shouta MM NAKAYAMA^1,5, Kawai K Yusuke⁶, Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Department of Environmental Veterinary Science, Graduate school of Veterinary Medicine, Hokkaido University, 2.Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa, 3.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, 4.One Health Research Center, Hokkaido University, 5.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, 6.Laboratory of Toxicology, Division of Veterinary Science, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine )

*Masafumi Katayama¹, Tomokazu Fukuda², Manabu Onuma¹, Kazuki Takeda³, Satomi Kondo⁴, Shouta MM NAKAYAMA^5,6 (1.National Institute for Environmental Studies, 2.Iwate University, 3.Kitasato University, 4.Everlasting Nature of Asia, 5.Hokkaido University, 6.School of Veterinary Medicine, The University of Zambia)

*Kraisiri Khidkhan¹, Saranya POAPOLATHEP¹, Sittinee KULPRASERTSRI¹, Rattapong SUKKHEEWAN¹, Paphatsara KHUNLERT², Shouta MM NAKAYAMA³, Amnart POAPOLATHEP¹ (1.Department of Pharmacology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand, 2.Agricultural Toxic Substance Research Group, Agricultural Production Sciences Research and Development Division, Department of Agriculture, Ministry of Agriculture and Cooperatives, 3.Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University)

*COLLINS NIMAKO¹, Anri HIRAI¹, Takahiro ICHISE¹, Shouta MM NAKAYAMA^1,2, Mayumi Ishizuka¹, Yoshinori IKENAKA^1,3,4,5 (1.Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan, 2.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, 3.Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa, 4.One Health Research Center, Hokkaido University, Hokkaido, Japan, 5.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan)