*Yared Beyene Yohannes¹, Shouta MM NAKAYAMA¹, John Yabe², Haruya Toyomaki¹, Andrew Kataba², Kaampwe Muzandu², Hokuto Nakata¹, Yoshinori Ikenaka¹, Kennedy Kennedy Choongo², Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Hokkaido University, Japan, 2.School of Veterinary Medicine, University of Zambia, Zambia)

*Nyein Chan Soe^1,2, Takamitsu Ohigashi³, Hokuto Nakata¹, Chikae Tatsumi³, Yoshitaka Uchida⁴, Walubita Mufalo⁵, Mayumi Ito⁶, Tsutomu Sato⁶, Toshifumi Igarashi⁶, Yared B Yohannes^1,7, Yoshinori Ikenaka^1,8,9,10, Mayumi Ishizuka¹, Shouta MM NAKAYAMA^1,11 (1.Laboratory of Toxicology, Department of Environmental Veterinary Science, Faculty of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo, 060-0818, Japan, 2.Department of Pharmacology and Parasitology, University of Veterinary Science, Yezin, Nay Pyi Taw, 15013, Myanmar, 3.Graduate School of Global Food Resources, Hokkaido University, Sapporo, 060-8589, Japan, 4.Global Center for Food, Land and Water Resources, Research Faculty of Agriculture, Hokkaido University, Sapporo, 060- 8589, Japan, 5.Graduate School of Engineering, Hokkaido University, Sapporo, 060- 8628, Japan, 6.Faculty of Engineering, Hokkaido University, Sapporo, 060- 8628, Japan, 7.Department of Chemistry, College of Natural and Computational Science, University of Gondar, Ethiopia, 8.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan , 9.One Health Research Center, Hokkaido University, Japan, 10.Water Research Group, School of Environmental Sciences and Development, North-West University, South Africa, 11.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, P.O. Box 32379, Lusaka 10101, Zambia)

*Rio Doya¹, Shouta MM Nakayama^1,2, Hokuto Nakata¹, John Yabe^2,3, Kaampwe Muzandu², Yoshinori Ikenaka^1,4,5, Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Faculty of Veterinary Medicine, Hokkaido University , 2.School of Veterinary Medicine, The University of Zambia, 3.Faculty of Health Sciences and Veterinary Medicine, School of Veterinary Medicine, University of Namibia, 4.One Health Research Center, Hokkaido University, 5.Unit for Environmental Sciences and Management, North-West University)

*Mitsuki Kondo¹, Yoshinori Ikenaka^1,2,3,4, Shouta MM NAKAYAMA^1,5, Kawai K Yusuke⁶, Mayumi Ishizuka¹ (1.Laboratory of Toxicology, Department of Environmental Veterinary Science, Graduate school of Veterinary Medicine, Hokkaido University, 2.Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa, 3.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, 4.One Health Research Center, Hokkaido University, 5.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, 6.Laboratory of Toxicology, Division of Veterinary Science, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine )

*COLLINS NIMAKO¹, Anri HIRAI¹, Takahiro ICHISE¹, Shouta MM NAKAYAMA^1,2, Mayumi Ishizuka¹, Yoshinori IKENAKA^1,3,4,5 (1.Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan, 2.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia, 3.Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa, 4.One Health Research Center, Hokkaido University, Hokkaido, Japan, 5.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan)