Materials derived from living organisms

[JO-1G04] Development of a systemically applicable adeno-associated virus (AAV)-loaded ternary complex that enables evasion from AAV neutralizing antibodies

〇Shuhei Nagao^1,2, Yuto Honda^1,2, Hiroaki Kinoh³, Takahiro Nomoto^1,2, Xueying Liu³, Anjaneyulu Dirisala³, Makoto Matsui², Yutaka Miura^1,2, Kazunori Kataoka³, Nobuhiro Nishiyama^1,2 (1. School of Life Science and Technology, Department of Life Science and Technology, Tokyo Institute of Technology (Japan), 2. Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology (Japan), 3. Innovation Center of Nanomedicine (iCONM), Kawasaki Institute of Industrial Promotion (Japan))

Keywords:Gene therapy, Adeno-associated virus(AAV), Boronic acid esters, Polyphenols, Self-assembly