[4T14L-09(3P0780)] RBM20 and RBM24 together regulate the splicing of PDLIM5 in cardiomyocyte

〇Jumpei Ito^1,2, Andres D. Maturana¹ (1.Graduate School of Bioagricultural Sciences, Nagoya University, 2.Japan Society for the Promotion of Science)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:05 PM - 1:15 PM

[4T14L-10(3P0781)] Interactome analysis of BRCA2-binding proteins on mitotic chromosomes

〇Nao Otsuka¹, Miho Takaoka¹, Akira Nakanishi¹, Yoshio Miki^1,2 (1.Dept.Mol.Genet.,Tokyo Med&Dent.Univ., 2.Dept.Mol.Diagnousis, JFCR. The Cancer Inst.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:15 PM - 1:25 PM

[4T14L-11(3P0782)] Rif1 regulates expression of cluster genes in mouse ES cells and reprogramming

〇Naoko Yoshizawa¹, Tomio Ono², Satoshi Yamazaki¹, mayumi Shindo², Yasumasa Nishito², Hisao Masai¹ (1.Genome Dynamics, Tokyo Met. Inst. Med. Sci, 2.Basic Tech. Res. Centr., Tokyo Met. Inst. Med.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:25 PM - 1:35 PM

[4T14L-12(3P0783)] The subnuclear dynamics of POP-1/TCF-targeted genes during development of C. elegans

〇Sohei Nakayama¹, Hitoshi Sawa¹ (1.NIG, Multicellular Organization Lab.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 1:35 PM - 1:45 PM

[4T15L-01(3P1231)] Loss of p62/SQSTM1 but not Nrf2 accelerates motor neuron degeneration in SOD1^H46R transgenic mice

〇Shun Mitsui¹, Mizuki Kubo¹, Lei Pan¹, Asako Otomo¹, Masato Koike², Yasuo Uchiyama², Masashi Aoki³, Masayuki Yamamoto⁴, Tetsuro Ishii⁵, Toru Yanagawa⁵, Hui-Fang Shang⁶, Fumihito Yoshii⁷, Shinji Hadano¹ (1.Dept Mol Life Sci, Tokai Univ Sch of Med, 2.Dept Cell Biol & Neurosci, Juntendo Univ Grad Sch of Med, 3.Dept Neurol, Tohoku Univ Grade Sch of Med, 4.Dept Med Biochem, Tohoku Univ Grade Sch of Med, 5.Facul Med, Univ of Tsukuba, 6.West China Hosp Sichuan Univ, China, 7.Dept Neurol, Tokai Univ Sch of Med)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 11:45 AM - 11:55 AM

[4T15L-02(3P1232)] Identification of chemical compounds inhibiting SOD1-Derlin-1 interaction for ALS treatment

〇Naomi Tsuburaya¹, Kengo Homma¹, Hidenori Ichijo¹ (1.Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 11:55 AM - 12:05 PM

[4T15L-03(3P1233)] RNA and nucleolar localization prevents toxicity and aggregation of carboxyl-terminal fragment of ALS-linked TDP43 via inhibition of the structural transition in Prion-like domain.

〇Akira Kitamura^1,2, Yusaku Nakayama², Ai Shibasaki², Ayami Taki², Sachiko Yuno², Masataka Kinjo^1,2 (1.Lab. of Mol. Cell Dyn., Fac. Adv. Life Sci., Hokkaido Univ., 2.Grad. Sch. of Life Sci., Hokkaido Univ.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:05 PM - 12:15 PM

[4T15L-04(3P1234)] TDP-43 Binds and Transports G-Quadruplex-Containing mRNAs into Neurites for Local Translation

〇Akira Ishiguro¹, Akira Ishihama¹, Nobuyuki Kimura² (1.Research Center for micro-nano tec., Univ. of Hosei, 2.Dept. of AD, Cent. for Dev. of Adv. Med. for Dementia, NCGG)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:15 PM - 12:25 PM

[4T15L-05(3P1235)] TDP-43 transports mRNA of ribosomal proteins

〇Seiichi Nagano¹, Sachiko Hirokawa², Masatoyo Nishizawa³, Kenji Sakimura⁴, Osamu Onodera², Toshiyuki Araki¹ (1.Dept. of PNS Res., Natl. Inst. of Neurosci., NCNP, 2.Dept. of Mol. Neurosci., Brain Res. Inst., Niigata Univ., 3.Dept. of Neurol., Brain Res. Inst., Niigata Univ., 4.Dept. of Cell. Neurobiol., Brain Res. Inst., Niigata Univ.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:25 PM - 12:35 PM

[4T15L-06(3P1236)] Selective deprivation of the toxic conformer of Aβ ameliorated behavioral abnormalities in Alzheimer' disease model without affecting senile plaque deposition

〇Izuo Naotaka¹, Kazuma Murakami², Masahiro Maeda³, Toshiaki Kume⁴, Koutaro Yokote¹, Kazuhiro Irie², Takahiko Shimizu¹ (1.Grad. Sch. Med., Chiba Univ., 2.Grad. Sch. Agri., Kyoto Univ., 3.Immuno-Biological Laboratories, 4.Grad. Sch. Pharm., Kyoto Univ.)

BMB2015 Biochemistry and Molecular Biology |Fri. Dec 4, 2015 12:35 PM - 12:45 PM