[1P0441] Analysis of MHC class I ligand peptide repertoire produced by the thymoproteasome

〇Kazuki Ohtake¹, Yuki Ohte², Katsuhiro Sasaki³, Shigeo Murata⁴ (1.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 2.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 3.Dept. of Mol. and Cell. Physiol., Grad. Sch. of Med., Univ. of Kyoto, 4.Grad. Sch. of Pharm. Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0442] Uncovering the mechanism for maintaining cellular homeostasis under proteasome inhibition

〇Eiichi Hashimoto¹, Jun Hamazaki¹, Shigeo Murata¹ (1.Grad.Sch.of Pharm. Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0443] Chemical screening for proteasome activators

〇Yuki Hashimoto¹, Shinichiro Egashira², Kiyoaki Yonesu², Muneki Isokawa³, Makoto Tsunoda³, Takashi Funatsu³, Takayoshi Okabe², Hirotatsu Kojima², Hideki Yashiroda¹, Shigeo Murata¹ (1.Lab. of Protein Metabolism, Grad. Sch. of Pharm Sci., Univ. of Tokyo, 2.Drug Discovery Initiative, Univ. of Tokyo, 3.Lab. of Bioanalytical Chemistry, Grad. Sch. of Pharm Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0444] The yeast endocytic protein Sla2 is involved in the 26S proteasome assembly

〇Taichi Fujita¹, Ryohei Shirozu², Hideki Yashiroda¹, Shigeo Murata¹ (1.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 2.Grad. Sch. of Med., Kyoto Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0445] Functional analysis of the budding yeast deubiquitylase Otu2

〇Chiho Fujimoto¹, Hideki Yashiroda¹, Shigeo Murata¹ (1.Dept. of Pharmaceu. Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0446] Molecular basis of immunoreceptor recognition by KSHV ubiquitin ligase MIR through the transmembrane helix-helix interaction

〇Aya Kuramoto¹, Mizuho Kajikawa¹, Minako Kimura¹, Hideaki Shima¹, Yoshihiro Inoue¹, Satoshi Ishido¹ (1.Lab. of Integrative Infect. Immunol., Showa Pharm. Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0447] Proteomic analysis of 26S proteasome reveals direct interaction with transit peptides of plastid protein precursors for degradation in Arabidopsis.

〇Yuki Yanagawa¹, Kaori Sako², Tomoyuki Kanai³, Takeo Sato³, Masayuki Fujiwara⁴, Yoichiro Fukao⁵, Junji Yamaguchi³ (1.Insect-Plant Int. Res. Unit, Natl. Inst. of Agrobiol. Sci., 2.Ctr. for Sustain. Res. Sci., RIKEN, 3.Grad. Sch. of Life Sci., Hokkaido Univ., 4.Inst. for Adv. Biosci., Keio Univ., 5.College of Life Sci., Ritsumeikan Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0448] PINK1 phosphorylated Ser65 ubiquitin regulates Parkin E3 activity

〇Fumika Koyano¹, Kei Okatsu², Hidetaka Kosako³, Mayumi Kimura¹, Hikaru Tsuchiya⁴, Hidehito Yoshihara⁴, Yasushi Saeki⁴, Keiji Tanaka^1,4, Noriyuki Matsuda¹ (1.Ubiquitin Project, Tokyo Metropolitan Institute of Medical Science, 2.The University of Tokyo, 3.Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, The University of Tokushima, 4.Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0449] Novel quality control system of cytosolic membrane protein

〇Eisuke Itakura^1,2, Ramanujan Hegde¹ (1.MRC Laboratory of molecular biology,, 2.Present address: Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0450] Functions of CRL5^ASB7 ubiquitin ligase in the maintenance of chromosomal stability

〇Keiji Uematsu¹, Fumihiko Okumura¹, Kunio Nakatsukasa¹, Takumi Kamura¹ (1.Div. of Biol. Sci., Grad. Sch. of Sci.,Univ. of Nagoya)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM