[3P-0440（4LT10-06）] Identification of an Awa-tea derived novel compound that suppresses NFAT signaling and underlying mechanism of its suppressive effect

〇Hiroyuki Mizuguchi¹, Tomohiro Nakano¹, Kohei Nishida¹, Noriko Kitamura², Masayuki Uchida^2,3, Hiromichi Fujino¹, Osamu Kaminuma⁴, Hiroyuki Fukui⁵ (1.Dept. Mol. Pharmacol. Inst. Biomed. Sci. Tokushima Univ. Grad. Sch., 2.Allergy Immunol. Proj. Tokyo Metropol. Inst. Med. Sci., 3.Food Sci. Res. Lab. Div. Res. and Develop. Meiji Co., Ltd, 4.Cent. Life Sci. Res. Univ. Yamanashi, 5.Dept. Mol. Stud. for Incurable Dis. Inst. Biomed. Sci. Tokushima Univ. Grad. Sch.)

ConBio2017

[3P-0441（4LT10-07）] Chemical genomic studies using genomewide profiling of FTY720 sensitivity reveal the involvement of the calcium and ROS signaling as its mechanisms of action

〇Kanako Hagihara¹, Kouki Ishida¹, Kanako Kinoshita¹, Yoshinori Kameoka¹, Shihomi Hojo¹, Ryosuke Satoh¹, Teruaki Takasaki¹, Reiko Sugiura¹ (1.Fac. of Pharm., Kindai Univ.)

ConBio2017

[3P-0442（4LT10-08）] Identification and functional analysis of Smad binding sequences by CASTing（cyclic amplification of selective target）method

〇Yuka Itoh¹, Chiho Omata¹, Mitsuyoshi Motizuki¹, Masao Saitoh¹, Keiji Miyazawa¹ (1.Dept. of Biochem., Grad. Sch. of Med., Univ. of Yamanashi)

ConBio2017

[3P-0443（4LT10-09）] Identification of nocistatin-binding proteins by using a photoaffinity probe

〇Masashi Harada¹, Toshiaki Minami², Seiji Ito³, Emiko Ashitaka¹ (1.Dept. of Biomedical. Eng., Osaka Inst. of Technol., 2.Dept. of Anesthesiol., Osaka Med. Col., 3.Dept. of Med. Chem., Kansai Med. Univ.)

ConBio2017

[3P-0444（4LT19-01）] Induction of Macropinocytic Cell Death by Oncogenic RAS in Human Epithelial Cells and Its Suppression by MYC Overexpression

〇Kasumi Otsubo^1,2, Takashi Yugawa¹, Tomomi Nakahara¹, Tohru Kiyono¹ (1.Div. of Carcinog. Cancer Prev., Natl. Cancer. Ctr. Res. Inst., 2.Grad. Sch. of Med. & Dent. Sci, TMDU)

ConBio2017

[3P-0445（4LT19-02）] Atypical mutations in C-terminal domain of KRas protein cause the cellular transforming ability with their unique biochemical characters

〇Kenji Tago¹, Megumi Funakoshi-Tago², Satoshi Ohta¹, Chihiro Aoki-Ohmura¹, Jitsuhiro Matsugi¹, Ken Yanagisawa¹ (1.Dept. of Biochem., Jichi Med. Univ., 2.Grad. Sch. of Pharm. Sci., Keio Univ.)

ConBio2017

[3P-0446（4LT19-03）] Functions of Wnt/Ras signal-dependent factor Arl4c in pancreatic cancer

〇Shinji Matsumoto¹, Toshiyuki Akama¹, Kensaku Shojima¹, Akira Kikuchi¹ (1.Dept of Mol. Biol. Biochem., The Univ. of Osaka)

ConBio2017

[3P-0447（4LT19-05）] Role of Notch signaling in adipose-derived mesenchymal stem cells under hypoxic condition

〇Kakeru Inoue¹, Mariko Moriyama¹, Norihito Kimura¹, Sumika Fujimura¹, Takumi Watada¹, Toshiyuki Ozawa², Takao Hayakawa¹, Hiroyuki Moriyama¹ (1.Pharm. Res. Technol. Inst., Kindai Univ., 2.Grad. Sch. of Med., Osaka city univ.)

ConBio2017

[3P-0448（4LT19-06）] Regulation of phagosomal acidification and microbial killing by tyrosine kinase Syk

〇Hiroyuki Tabata¹, Hiroyuki Morita¹, Yumi Tohyama¹ (1.Divi. of Biochem., Dept. of Pharm., Univ. of Himeji Dokkyo)

ConBio2017

[3P-0449（4LT19-07）] Identification of ASK3 as a novel regulator of cell volume regulation and mGluR5 as a regulator of ASK3

〇Kuniyoshi Niwa¹, Kengo Watanabe¹, Isao Naguro¹, Hidenori Ichijo¹ (1.Cell Signaling, Grad. Sch. of Pharmaceut. Sci., Univ. of Tokyo)

ConBio2017