[4LT02-01（3P-1091）] Functional analysis of Rab7 and its effecter proteins in Aβ secretion

〇Hiroto Ozama¹, Nobuyuki Kawamura², Ge-Hong Sun-Wada², Yoh Wada³, Taisuke Tomita¹ (1.Dept. of Pharm. Sci., The Univ. of Tokyo, 2.Dept. of Pharm. Biochem., Doshisha Univ., 3.Dept. of Biomol. Sci. and Reac., Osaka Univ.)

ConBio2017 |Sat. Dec 9, 2017 11:45 AM - 11:55 AM

[4LT02-02（3P-1092）] The analysis of APP-βCTF mediated vesicle traffic impairment

〇Nanaka Kaneshiro¹, Takashi Uehara¹, Nobumasa Takasugi ¹ (1.Dept. Medicinal Pharmacol., Grad. Sch. Med. Den. Pharmaceutical Sci., Univ. of Okayama)

ConBio2017 |Sat. Dec 9, 2017 11:55 AM - 12:05 PM

[4LT02-03（3P-1093）] In vivo identification and characterization of A beta pathology-dependent Tau-binding proteins

〇Ayano Ishii^1,2, Shoko Hashimoto¹, Yukio Matsuba¹, Naomi Mihira¹, Akihiko Takashima³, Shinichi Muramatsu⁴, Makoto Yokosuka², Takashi Saito¹, Takaomi Saido¹ (1.PNS., BSI. of RIKEN, 2.Dept. of Vet. Med., Grad. Sch. of Vet. Med., Univ. of NVLU, 3.Dept. of Life Sci., Fac. of Sci., Univ. of Gakushuin, 4.Div. of Neurology, Dept. of Med., Univ. of Jichi Med.)

ConBio2017 |Sat. Dec 9, 2017 12:05 PM - 12:15 PM

[4LT02-04（3P-1088）] Role of cysteine residues in microtubule-binding protein tau in its metabolism and toxicity

〇Tomoki Chiku¹, Mikiko Oka², Akio Sumioka³, Taro Saito^1,2, Akiko Asada^1,2, Shinichi Hisanaga^1,2, Koichi Ijima^4,5, Akihiko Takashima³, Kanae Ando^1,2 (1.Div. of Biol. Sci., Sch. of Sci. and. Eng., Univ. of Tokyo Metoropolitan, 2.Dept. of Biol. Sci., Grad. Sch. of Sci. and. Eng., Univ. of Tokyo Metropolitan, 3.Grad. in Life Sci., Grad. Sch. of Sci., Univ. of Gakushuin, 4.NCGG, Dept of Alzheimer's Disease Research, 5.Grad. Sch. of Phamaceutical Sci., Dept. of. Experimental Gerontology., Univ. of Nagoya City)

ConBio2017 |Sat. Dec 9, 2017 12:15 PM - 12:25 PM

[4LT02-05（3P-1089）] Analyses of roles of CaMKII in neurodegeneration caused by depletion of axonal mitochondria

〇Kanako Shinno¹, Mikiko Oka², Akiko Asada^2,3, Taro Saito^2,3, Shinichi Hisanaga^2,3, Emiko Suzuki^4,5, Koichi M. Iijima^6,7, Kanae Ando^2,3 (1.Dept. of Biol. Sci., Sch. of Sci., Univ. of Kitasato, 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Tokyo Metropolitan Univ., 3.Dept. of Biol. Sci., Sch. of Sci.Eng., Tokyo Metropolitan Univ., 4.NIG, Gene Network Lab., 5.SOKENDAI, 6.NCGG, Dept. of Alzheimer's Disease Research, 7.Grad. Sch. Pharmaceutical Sci., Nagoya City Univ.)

ConBio2017 |Sat. Dec 9, 2017 12:25 PM - 12:35 PM

[4LT02-06（3P-1094）] Molecular mechanisms for the axonal localization of Tau protein in neurons

〇Minori Iwata¹, Shoji Watanabe¹, Tomohiro Miyasaka², Hongsun Park³, Hiroaki Misonou¹ (1.Graduate School of Brain Science, Doshisha University, 2.Faculty of Life and Medical Sciences, Doshisha University, 3.Graduate School of Brain Science, Doshisha University)

ConBio2017 |Sat. Dec 9, 2017 12:35 PM - 12:45 PM

[4LT02-07（3P-1095）] Pathological analysis of central nervous system in dystroglycanopathy mouse models

〇Atsushi Sudo¹, Motoi Kanagawa¹, Mai Kondo¹, Kazuhiro Kobayashi¹, Mitsuharu Endo², Yasuhiro Minami², Tatsushi Toda^1,3 (1.Div. of Neurol./Mol. Brain Sci., Kobe Univ. Grad. Sch. of Med., 2.Div. of Cell Physiol., Kobe Univ. Grad. Sch. of Med., 3.Dept. of Neurol., Grad. Sch. of Med., Univ. of Tokyo)

ConBio2017 |Sat. Dec 9, 2017 12:45 PM - 12:55 PM

[4LT02-08（3P-1096）] Guanine oxidization of G-quadruplex exhibits TDP-43 dependent mRNA transport

〇Akira Ishiguro¹, Takashi Noma², Nubuyuki Kimura³, Takahide Kon² (1.Research Center for Micro-Nano Tech., Hosei Univ., 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ.., 3.Sec.for Cel. Biol. Path., Dep. of Alz., NCGG.)

ConBio2017 |Sat. Dec 9, 2017 12:55 PM - 1:05 PM

[4LT02-09（3P-1097）] A copper-deficient form of mutant SOD1 as an early pathological species in amyotrophic lateral sclerosis

〇Yoshiaki Furukawa¹, Eiichi Tokuda¹, Shinji Ohara², Koji Yamanaka³, Hidemi Misawa⁴ (1.Dept. of Chem., Keio Univ., 2.Dept. of Neurol., Matsumoto Medical Center, 3.Res. Inst. of Environ. Med., Nagoya Univ., 4.Div. Pharm., Keio Univ.)

ConBio2017 |Sat. Dec 9, 2017 1:05 PM - 1:15 PM

[4LT03-01（3P-0082）] Integrative approach combining electron microscopy and high speed-AFM revealed the dynamic conformational exchange of the oligosaccharyltransferase in lipid bilayers

〇Yuki Kawasaki¹, Kouta Mayanagi¹, Ashutosh Srivastava², Hirotaka Ariyama⁴, Florence Tama^2,3, Toshio Ando^4,5, Daisuke Kohda¹ (1.Div. Struct. Biol. of Med. Inst. Bioreg., Kyushu Univ., 2.Dept. of Phys., Grad Sch. of Sci., Nagoya Univ., 3.AICS., RIKEN, 4.Bio-AFM Frontier Research Center., Kanazawa Univ., 5.Dept. of Phys., Kanazawa Univ.)

ConBio2017 |Sat. Dec 9, 2017 11:45 AM - 11:55 AM