[3P-1417（3AT25-01）] Analysis of small molecule claudin-4 binder identified by time-resolved fluorescence resonance energy transfer

〇Yuta Sakamoto¹, Akihiro Watari¹, Miki Kodaka¹, Kota Hisaie¹, Kiyohito Yagi¹, Masuo Kondoh¹ (1.Grad. Sch. of Pharm, Univ. of Osaka)

ConBio2017

[3P-1418（3AT25-02）] Synthetic ligands that induce protein translocation to endomembranes in living cells: development and application to reversible control of endomembrane Ras signaling

〇Shunsuke Sawada¹, Rika Katahira¹, Akinobu Nakamura², Tatsuyuki Yoshii², Shinya Tsikiji^2,3 (1.Dept. of Bio., Grad. Sch. of Eng., Nagaoka Univ. of Technol., 2.Dept. of Life Sci. and Applied Chem., Grad. Sch. of Eng., Nagoya Inst. of Technol., 3.Frontier, Nagoya Inst. of Technol.)

ConBio2017

[3P-1419（3AT25-03）] Drug Discovery by Re-searching Cancer Metabolism and Microenvironment

〇Masayasu Toyomoto¹, Asuka Inoue², Kei Iida¹, Masatsugu Denawa¹, Isao Kii¹, Keiko Hayashi¹, Takayuki Kishi², Hiroshi Onogi¹, Suguru Yoshida³, Takamitsu Hosoya³, Junken Aoki², Masatoshi Hagiwara¹ (1.Grad. Sch. of Med., Univ. of Kyoto, 2.Grad. Sch. of Pharm. Sci., Univ. of Tohoku, 3.IBB, TMDU)

ConBio2017

[3P-1420（4AT26-08）] High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway

〇Seiji Ishii¹, Kenji Fukui¹, Satoshi Yokoshima², Kazuo Kumagai^3,4, Youko Beniyama², Tetsuya Kodama², Tohru Fukuyama², Takayoshi Okabe³, Tetsuo Nagano³, Hirotatsu Kojima³, Takato Yano¹ (1.Dept. of Biochem., Osaka Med. College, 2.Grad. Sch. Pharm. Sci., Nagoya Univ., 3.Drug Discovery Initiative, Univ. of Tokyo, 4.Grad. Sch. Eng., Kobe Univ.)

ConBio2017

[3P-1421（4AT26-09）] Glycolipozyme MPIase involved in membrane protein integrase is essential for cell growth

〇Katsuhiro Sawasato¹, Ryo Sato¹, Hanako Nishikawa¹, Naoki Iimura¹, Kohki Fujikawa², Toshiyuki Yamaguchi², Yutetsu Kuruma³, Yasushi Tamura⁴, Toshiya Endo⁵, Takuya Ueda⁶, Keiko Shimamoto², Ken-ichi Nishiyama¹ (1.Cryobiofrontier Research Center, Faculty of Agriculture, Iwate University, 2.Bioorganic Research Institute, Suntory Foundation for Life Sciences, 3.Earth-Life Science Institute, Tokyo Institute of Technology, 4.Faculty of Science, Yamagata University, Yamagata, 5.Faculty of Life Sciences, Kyoto Sangyo University, 6.Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo)

ConBio2017

[3P-1422（4AT26-10）] Development of novel diagnosis system based on single enzyme activity monitoring in micro-device

〇Shingo Sakamoto¹, Toru Komatsu^1,5, Rikiya Watanabe^4,5, Zhang Yi⁴, Hiroyuki Noji⁴, Yasuteru Urano^1,2,3 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.Grad. Sch. Med. Sci., The Univ. Tokyo, 3.AMED CREST, 4.Grad. Sch. Eng. Sci., The Univ. Tokyo, 5.JST PRESTO)

ConBio2017

[3P-1423（4AT26-11）] Sequence-selective inhibition of DNA methylation using DNA-binding small molecules

〇Ken-ichi Shinohara¹, Natsumi Yoda¹, Masaki Fukuyo¹, Kazuko Kita¹, Tetsuhiro Nemoto², Atsushi Kaneda¹ (1.Dept. of Mol. Oncol., Grad Sch. of Med., Chiba Univ., 2.Dept. of Pharm. Chem., Grad Sch. of Pharm. Sci., Chiba Univ.)

ConBio2017

[3P-1424（4AT26-12）] Establishment of the strategy of comprehensive analysis of peptide metabolizing enzymatic activities

〇Yuki Ichihashi¹, Jun Onagi¹, Toru Komatsu^1,4, Mako Kamiya^2,4, Hiroyuki Matsuzaki³, Keisuke Hata³, Watanabe Toshiaki³, Yasuteru Urano^1,2,5 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.Grad. Sch. Med., The Univ. Tokyo, 3.Dep. Surg. Onco., Grad. Sch. Med., The Univ. Tokyo, 4.JST, PRESTO, 5.AMED, CREST)

ConBio2017

[3P-1425（4AT26-15）] Screening of PPI inhibitors against P-cadherin, the protein forming homo-dimer

〇Akinobu Senoo¹, Takumi Tashima¹, Shota Kudo¹, Satoru Nagatoishi³, Kouhei Tsumoto^2,3 (1.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 2.Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 3. Inst. of Med. Sci., Univ. of Tokyo )

ConBio2017

[3P-1426] Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

〇Lai Yue Chan¹, David J. Craik¹, Norelle L. Daly² (1.The University of Queensland, Institute for Molecular Bioscience, Australia., 2.Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Australia.)

ConBio2017