[1P-406] Development of treatment method of Sandhoff disease mouse model that is one of lysosomal storage diseases

^○Kyoko Suzuki¹, Akira Yamaguchi², Shoji Yamanaka², Makoto Kawashima², Seiichi Kanzaki², Noriko Koumitsu³, Mayumi Minamisawa⁴, Naoya Aoki¹, Omi Katsuse¹, Yoshio Hirayasu¹ (1.Dept. of Psycho. Sch. of Med. The Univ. of Yokohama City, 2.Dept. Pathol. Sch. of Med. The Univ. of Yokohama City, 3.Dept. Dematol. Sch. of Med. The Univ. of Yokohama City, 4.Chiba Inst. Techno Univ.)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 1:30 PM - 2:45 PM

[1P-407] Diagnostic method for X-linked adrenoleukodystrophy using LC-MS/MS

^○Mashima Ryuichi¹, Misa Tanaka¹, Eri Sakai¹, Motomichi Kosuga^1,2,3, Torayuki Okuyama^1,2 (1.Dept Clin Lab Med, Natl Ctr Child Health Dev, 2.Ctr Lys Stor Dis, Natl Ctr Child Health Dev, 3.Div Med Genet, Natl Ctr Child Health Dev)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 2:45 PM - 3:45 PM

[1P-408(1T18-06)] Development of a new cereblon modulator for acute myeloid leukemia

^○Takumi Ito^1,2, Hiroshi Handa¹ (1.Dept. of Nano. Transl. Res., Tokyo Med. Univ., 2.JST-PRESTO)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 1:30 PM - 2:45 PM

[1P-409] In vitro screening for drug repositioning to identify semaphorin3A expression regulator

^○Yayoi Kamata, Mitsutoshi Tominaga, Azumi Sakaguchi, Yoshie Umehara, Kenji Takamori (Inst. for Env. and Gen. Med, Juntendo Univ. Grad.Sch.of Med.)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 2:45 PM - 3:45 PM

[1P-410] Functional characterization of monoclonal antibody targeting endothelial cell

^○Takeshi Fukuhara¹, Jia Kim^2,3, Shintarou Hokaiwado^1,3, Tetsuro Watabe² (1.Dep. of Therapeutic Development for Intractable Neurological Diseases, Juntendo University, 2.Section of Cellular Biochemistry, Tokyo Medical and Dental University, 3.Lab. of Oncology, Tokyo University of Pharmacy and Life Sciences)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 1:30 PM - 2:45 PM

[2P-001] Studies on discovery of novel molecules against HMGB1/LPS-induced inflammation

^○Shingo Nakajima¹, Kenya Tamada¹, Akira Sato^1,2, Atsushi Yoshimori³, Takako Ichiki⁴, Fumihiko Sasaki⁴, Takehiko Yokomizo⁴, Sei-ichi Tanuma^1,2 (1.Dept. Biochem., Fac. Pharm. Sci., Tokyo Univ. Sci., 2.Genome and Drug Res. Center, Tokyo Univ. Sci., 3.Institute for Theoretical Medicine, Inc., 4.Dept. of Biochemistry, Juntendo Univ.)

The 89th Annual Meeting of JBS |Mon. Sep 26, 2016 1:30 PM - 2:45 PM

[2P-002] The function of MEGF10 in neurons.

^○Yu Fujita¹, Tomoji Maeda², Kun Zou¹, Hiroto Komano¹ (1.Department of Neuroscience, School of Pharmacy, Iwate Medical University, 2.Department of Pharmcology, Nihon Pharmaceutical Uniersity)

The 89th Annual Meeting of JBS |Mon. Sep 26, 2016 2:45 PM - 3:45 PM

[2P-003] Phosphatidylinositol phosphate is involved in regulation of calcium channel activity in yeast vacuolar membrane

^○Shin Hamamoto¹, Isamu Yabe², Yasuo Mori³, Nobuyuki Uozumi¹ (1.Grad. Sch. Eng., Tohoku Univ., 2.Tokyo Denki Univ., 3.Grad. Sch. Eng., Kyoto Univ.)

The 89th Annual Meeting of JBS |Mon. Sep 26, 2016 1:30 PM - 2:45 PM

[2P-004] Patched1 intracellular domain-binding proteins modulate Sonic hedgehog signaling.

^○Setsuya Minami, Yuka Yamaki, Akane Iwasaki, Hiroki Kagawa, Hiroyuki Kawahara (Dep. Biol. Sci., Grad. Sch. Sci. Eng., Tokyo Mtropol. Univ.)

The 89th Annual Meeting of JBS |Mon. Sep 26, 2016 2:45 PM - 3:45 PM

[2P-005] Function of extracellular cysteine residues of the ATP/UTP receptor P2Y2

^○Maya Abe, Kanae Watanabe, Yoshiyuki Kuroda, Tetsuto Nakagawa, Hideyoshi Higashi (Div. of Glyco-Signal.Res.,Inst. of Mol.Biomembr.Glycobiol., Tohoku Med. Pharm. Univ.)

The 89th Annual Meeting of JBS |Mon. Sep 26, 2016 1:30 PM - 2:45 PM