[1T08-03(1P-047)] Conjugation of synthetic N-glycans to recombinant human lysosomal enzymes derived from transgenic silkworms and therapeutic application for lysosomal diseases

^○So-ichiro Nishioka^1,9, Isao Kobayashi^3,9, Akira Harazono^4,10, Yuhki Kubo⁵, Yuji Matsuzaki⁶, Nobuo Maita⁷, Tomo Hidaka², Daisuke Tsuji^1,9, Hideki Sezutsu^3,9,10, Hiroaki Machii^3,9, Akiko Ishii^4,10, Nana Kawasaki^8,10, Kohji Itoh^1,9,10 (1.Grad. Sch. of Pharmaceut Sci., Tokushima Univ., 2.Facult. of Pharmaceut Sci., Tokushima Univ., 3.NARO, 4.NIHS, 5.Masuda Chem. Inds. Co., Ltd., 6.Tokyo Chem. Inds. Co., Ltd., 7.Inst. for Enz. Res., Tokushima Univ., 8.Grad. Sch. of Med. Life Sci., The Univ. of Yokohama City, 9.Agrihealth PT, 10.AMED)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:14 AM - 9:26 AM

[1T08-04(1P-045)] Functional analysis of mucin-type O-glycans in Drosophila muscle and neuromuscular junction

^○Kazuyoshi Itoh¹, Yoshihiro Akimoto², Takashi Fuwa¹, Shoko Nishihara¹ (1.Department of Bioinformatics, Graduate school of Engineering, Soka University, 2.Department of Anatomy, Kyorin University School of Medicine)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:26 AM - 9:38 AM

[1T08-05(1P-040)] N-glycan-Mediated Domain Formation of Nutrition Sensors on Pancreatic β Cell Surface

^○Kento Maeda¹, Masayoshi Tasaki^2,3, Yukio Ando³, Kazuaki Ohtsubo¹ (1.Dept. of Anal. Bioc., Fac. of Life Sci., Univ. of Kumamoto, 2.Dept. of Morphol. and Physiol. Sci., Div. of Info. Clin. Sci., Grad. Sch. of Med. Sci., Univ. of Kumamoto, 3.Dept. of Neurol., Grad. Sch. of Med. Sci., Univ. of Kumamoto)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:38 AM - 9:50 AM

[1T08-06(1P-044)] The importance of N-glycosylation on integrin β1 in its activation and complex formation

^○Sicong Hou, Tomoya Isaji, Qinglei Hang, Tomohiko Fukuda, Jianguo Gu (Div. Reg. Glycobio., pharm. sci., Tohoku Med. Pharm. Univ.)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:50 AM - 10:02 AM

[1T08-07(1P-046)] Extracellular O-GlcNAc regulates Delta-like 4 mediated Notch signaling and vascular development in mammals

^○Shogo Sawaguchi¹, Mitsutaka Ogawa¹, Hirokazu Yagi², Koichi Kato^2,3, Tetsuya Okazima¹ (1.Dept. Biochem. II, Nagoya Univ. Grad. Sch. of Med, 2.Nagoya City Univ. Grad. Sch. of Pharma, 3.Okazaki Inst. for Integr. Biosci., Nat. Inst. of Nat. Sci)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 10:02 AM - 10:14 AM

[1T09-01(1P-073)] Biochemical and lipidomic analysis of N-acyl phospholipid-metabolizing enzyme ABHD4

^○Hyeon-Cheol Lee^1,2, Benjamin Cravatt², Takehiko Yokomizo¹ (1.Dept. of Biochem., Grad. Sch. of Med., Juntendo Univ., 2.The Scripps Research Institute)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 8:50 AM - 9:02 AM

[1T09-02(1P-068)] Evaluating substrates of intracellular phospholipase A by newly analytical method

^○Hiroki Kawana¹, Junken Aoki^1,2 (1.Lab. of Mol. and Cell. Biochem., Grad. Sch. of Pharm. Sci., Tohoku Univ., 2.AMED-CREST)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:02 AM - 9:14 AM

[1T09-03(1P-071)] The role of oxidized phospholipid-derived lipid mediators in IgE-mediated mast cell activation

^○Yuta Shimanaka¹, Nozomu Kono^1,2, Yoshitaka Taketomi³, Makoto Arita⁴, Makoto Murakami^3,5, Hiroyuki Arai^1,5 (1.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Japan, 2.PRIME, AMED, 3.Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Japan, 4.Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Japan, 5.AMED-CREST, AMED)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:14 AM - 9:26 AM

[1T09-04(2P-104)] Protective role of PAF-AH2, an oxidized phospholipid-selective phospholipase, in high-fat diet-induced hepatic steatosis

^○Yuki Tanaka (The Univ. of Tokyo , Graduate School of Pharmaceutical Sciences)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:26 AM - 9:38 AM

[1T09-05(1P-069)] sPLA₂-IID deficiency exacerbates metabolic syndrome.

^○Hiroyasu Sato¹, Ayako Ushida¹, Yoshitaka Taketomi¹, Yoshimi Miki¹, Makoto Murakami^1,2 (1.Lipid Metab,, Tokyo Metro. Inst. of Med. Sci., 2.AMED-CREST)

The 89th Annual Meeting of JBS |Sun. Sep 25, 2016 9:38 AM - 9:50 AM