[P-465(1Z07-09)] Elucidation of the Nucleosomal H4K20 Methylation Mechanism by Monomethyltransferase SET8

^○Cheng-Han Ho^1,2, Yoshimasa Takizawa¹, Wataru Kobayashi^1,3, Yasuhiro Arimura¹, Hiroshi Kimura⁴, Hitoshi Kurumizaka^1,2,3 (1.IQB, The University of Tokyo, 2.Graduate School of Science, The University of Tokyo, 3.Graduate School of Advanced Science and Engineering, Waseda University, 4.Institute of Innovative Research, Tokyo Institute of Technology)

The 93rd Annual Meeting of JBS

[P-466] p53 counteracts EZH2 at the nuclear lamina to prevent H3K27 hypermethylation

^○Tsukasa Oikawa¹, Naomi Ohnishi², Yasuhito Onodera¹, Ari Hashimoto¹, Koji Ueda², Hisataka Sabe¹ (1.Department of Molecular Biology, Graduate School of Medicine, Hokkaido University, 2.Project for Personalized Cancer Medicine, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research)

The 93rd Annual Meeting of JBS

[P-467] N-terminus variants of Bcnt/Cfdp1, a transient chromatin remodeler: DEF/Y motif core that is adjacent to the CK2 phosphorylation sites.

^○Shintaro Iwashita¹, Takehiro Suzuki², Yuuki Uezato³, Yasunori Sugiyama³, Naoshi Dohmae², Yoshiharu Ooka¹, Si-Young Song¹, Kentaro Nakashima¹ (1.Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ., 2.Biomol. Characterization Unit, CSRS, RIKEN, 3.Dept. Appl. Biol. Sci., Fac. Agr., Kagawa Univ.)

The 93rd Annual Meeting of JBS

[P-468] Structural dynamics of IDP region of heterochromatin protein HP1 studied by spin labeling ESR spectroscopy: DNA binding to hinge region and phosphorylation of N-terminal region

^○Toshiaki Arata^1,3, Kazunobu Sato², Ena Hirai², Risa Mutoh^3,6, Yuichi Mishima³, Takeji Takui², Toru Kawakami³, Hironobu Hojo³, Toshimichi Fujiwara³, Makoto Miyata¹, Isao Suetake^4,5 (1.Dept. Biol., Grad. Sch. Sci., Osaka City Univ., 2.Dept. Chem., Grad. Sch. Sci., Osaka City Univ., 3.Inst. Prot. Res., Osaka Univ., 4.Grad. Sch. Nut. Sci., Nakamura Gakuen Univ., 5.Ctr. Twin Res., Grad. Sch. Med., Osaka Univ., 6.Dept. Phys., Fac. Sci., Fukuoka Univ.)

The 93rd Annual Meeting of JBS

[P-469] The mechanism of human CENP-A deposition complex formation by HJURP and the Mis18 complex

^○Dongqing Pan¹, Kai Walstein², Annika Take², David Bier², Nadine Kaiser², Andrea Musacchio² (1.Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kyoto University, 2.Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany)

The 93rd Annual Meeting of JBS

[P-470(1Z07-10)] Analysis of DNA binding pattern of nuclear transport factor importin α via a novel domain

^○Kazuya Jibiki¹, Takashi Kodama², Atsushi Suenaga³, Yota Kawase¹, Noriko Shibazaki³, Noriko Saito⁴, Noriko Yasuhara³ (1.Graduate School of Integrated Basic Sciences, Nihon University, 2.Laboratory of Molecular Biophysics, Institute for Protein Research, Osaka University, 3.Department of Biosciences, College of Humanities and Sciences, Nihon University, 4.Division of Cancer Biology, The Cancer Institute of JFCR)

The 93rd Annual Meeting of JBS

[P-471] Polyamine-mediated translational regulation of Klf4 gene

^○Kazuhiro Nishimura^1,2, Moemi Okamoto², Rina Shibue², Toshihiko Toida², Kazuei Igarashi^2,3 (1.School of Pharmacy, International University of Health and Welfare, 2.Graduate School of Pharmaceutical Sciences, Chiba University, 3.Amine Pharma Research Institute)

The 93rd Annual Meeting of JBS

[P-472] The novel lncRNA affects polysome association of YB-1 in liver.

^○Toru Tanaka, Sachiyo Ohashi, Shunsuke Kobayashi (Dept. of Biochem., Sch. of Pharm., Nihon Univ.)

The 93rd Annual Meeting of JBS

[P-473] Methylation analysis of the affinity-purified C.elegans tRNAiMet by LC-MS/MS

^○Koichiro Kako¹, Daisuke Nakahara², Hiroaki Daitoku³, Akiyoshi Fukamizu³ (1.Faculty of Life and Environmental Sciences, University of Tsukuba, 2.Graduate School of Life and Environmental Sciences, University of Tsukuba, 3.Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA))

The 93rd Annual Meeting of JBS

[P-474] The antifibrotic effects of of CNOT6L deadenylase in pressure overload-induced cardiac remodeling

^○Tomokazu Yamaguchi¹, Teruki Sato^1,2, Takafumi Minato¹, Jianbo An¹, Midori Hoshizaki³, Hiroyuki Watanabe², Yumiko Imai³, Tadashi Yamamoto⁴, Keiji Kuba¹ (1.Department of Biochemistry and Metabolic Science, Akita University Graduate School of Medicine, 2.Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, 3.Laboratory of Regulation of Intractable Infectious Diseases, National Institute of Biomedical Innovation, Health and Nutrition, 4.Okinawa Institute of Science and Technology Graduate University)

The 93rd Annual Meeting of JBS