[P-756] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation

^○Ikumi Wakabayashi^1,2, Yasuhiro Yoshimatsu^1,3, Shiori Kimuro¹, Naoya Takahashi¹, Kazuki Takahashi¹, Fumiko Ito², Miho Kobayashi¹, Katarzyna A. Inoue¹, Kohei Miyazono⁴, Tetsuro Watabe¹ (1.Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University,, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, 4.Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo)

The 93rd Annual Meeting of JBS

[P-757] Novel mechanisms of gefitinib-induced suppression of cancer cell invasion through the ALB formation

^○Yuto Sekiguchi, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 93rd Annual Meeting of JBS

[P-758(1Z07-11)] Structural and kinetic analysis of CO binding to bacterial heme-responsive sensor protein

^○Yudai Nishitani¹, Megumi Nishinaga¹, Seina Nagai¹, Hiroshi Sugimoto^1,2, Takehiko Tosha^1,2, Yoshitsugu Shiro¹, Hitomi Sawai^1,2 (1.Department of Life Science, University of Hyogo, 2.RIKEN SPring-8 center)

The 93rd Annual Meeting of JBS

[P-759] Functional analysis of the Kinase module of human Mediator complex using an in vitro reconstitution system

^○Yusaku Kaido¹, Sora Harako¹, Hiroto Hayashi¹, Aki Tanaka¹, Yoshiaki Ohkuma², Yutaka Hirose¹ (1.Grad. Sch. of Med. & Pharm.Sci., Univ. of Toyama, 2.Genome Pharmaceuticals Institute)

The 93rd Annual Meeting of JBS

[P-760] Test for imprinted DNA methylation activity of the human H19-ICR sequence in YAC transgenic mice

^○Hitomi Matsuzaki^1,2, Katsuhiko Hirakawa¹, Keiji Tanimoto^1,2 (1.Faculty of Life and Environmental Sci., Univ. of Tsukuba, 2.TARA Center, Univ. of Tsukuba)

The 93rd Annual Meeting of JBS

[P-761] Distinction between Neolithic sheep and goat by mass spectrometry of type-I collagen preserved in bone specimens

Mako Inuzuka¹, Mao Karino¹, Momoko Osawa², Seiji Kadowaki², Yoshihiro Nishiaki³, ^○Takashi Nakazawa¹ (1.Nara Women's University, 2.Nagoya University, 3.The University of Tokyo)

The 93rd Annual Meeting of JBS

[P-762(3Z09-07)] A Comprehensive Study of Human Death Domain-fold Superfamily Interactome Using Cell-free Synthesized Protein Array and AlphaScreen.

^○Wei Zhou¹, Tomoya Nakagita², Naoe Kaneko¹, Hiroyuki Takeda², Junya Masumoto¹ (1.Grad Sch of Med, Ehime Univ., 2.PROS, Ehime Univ.)

The 93rd Annual Meeting of JBS

[P-763(2Z12-08)] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

^○Shingo Sakamoto¹, Toru Komatsu¹, Rikiya Watanabe², Zhang Yi³, Taiki Inoue¹, Mitsuyasu Kawaguchi⁴, Hidehiko Nakagawa⁴, Takaaki Ueno⁵, Takuji Okusaka⁶, Kazufumi Honda⁷, Hiroyuki Noji^3,8, Yasuteru Urano^1,9,10 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.RIKEN, 3.Grad. Sch. Eng., The Univ. Tokyo, 4.Grad. Sch. Pharm. Sci., Nagoya City Univ., 5.Osaka Dent. Univ., 6.Natl. Cancer Ctr. Hosp., 7.Natl. Cancer Ctr. Res. Inst., 8.ImPACT, 9.Grad. Sch. Med., The Univ. Tokyo, 10.AMED-CREST)

The 93rd Annual Meeting of JBS

[P-764(2Z12-10)] Correlation between dimerization and antifungal activity of rice defensin

^○Masami Suzuki¹, Kodai Ogawa¹, Toshiaki Sakurai², Masayuki Taniguchi³, Takaaki Tanaka^1,2, Yoshiyuki Sagehashi⁴, Akihito Ochiai^1,2 (1.Grad. Sch. of Sci. Technol., Niigata Univ., 2.Dep. of Mat. Technol., Niigata Univ., 3.Dep. of Liv. Stu., Niigata Seiryo Jnr. Col., 4.NARO Hokkaido Agr. Res. Cent.)

The 93rd Annual Meeting of JBS

[P-765] Effects of eyestalk ablation on the levels of D-amino acids in the testis of kuruma prawn Marsupenaeus japonicus

^○Naoko Yoshikawa, Natsuki Yoshitomi, Kazuki Nakada (Department of Materials and Life Science, Faculty of Science and Technology, Shizuoka Institute of Science and Technology)

The 93rd Annual Meeting of JBS