[1P-634(1T18a-07)] Drug discovery focused on regulation of NET release

^〇Madoka Ono¹, Masayasu Toyomoto^1,2,3, Momono Yamauchi¹, Masatoshi Hagiwara¹ (1.Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, 2.Department of Drug Discovery for Lung Diseases, Graduate School of Medicine, Kyoto University, 3.Department of Drug Discovery for Intractable Diseases, Graduate School of Medicine, Kyoto University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-635] Identification of novel inhibitors of metal-dependent protein phosphatase 1A

^〇Taketomo Suzuki¹, Osamu Niyomura², Motoko Ohnishi¹ (1.Graduate School of Bioscience and Biotechnology, Chubu Univ, 2.College of Engineering, Chubu Univ)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-636(1T18a-04)] Binding properties of the temperature-responsive elastin-like peptide (FPGVG)₅ analog to aromatic compounds present in the environment

^〇Keitaro Suyama¹, Masayuki Murashima², Iori Maeda³, Takeru Nose^1,2 (1.Faculty of Arts and Science, Kyushu University, 2.Department of Chemistry, Faculty and Graduate School of Science, Kyushu University, 3.Department of Physics and Information Technology, Kyushu Institute of Technology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-637] Screening for compounds that regulate dedifferentiation of prostate cancer cells based on the intracellular ALDH activity

^〇Reiji Nakatani¹, Yuka Takashima¹, Keiji Hasumi¹, Eriko Suzuki¹ (Tokyo University of Agriculture and Technology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-638(1T18a-02)] Development of a novel cell surface labeling method "CS-PeARL" and its application to protein conformational analysis

^〇Ayuka Deguchi¹, Akira Nagabukuro¹, Koji Sakai², Yuki Nishikawa², Tamami Uejima¹, Masaki Tanaka¹, Takashi Hayashi¹ (1.Department of Lead Discovery Research, Otsuka Pharmaceutical Co., Ltd., 2.Department of Medicinal Chemistry, Otsuka Pharmaceutical Co., Ltd.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-639] Affinity improvement of methylated antigen-specific antibody based on physicochemical analyses

^〇Yuka Miura¹, Takanori Yokoo², Makoto Nakakido^1,2, Kohei Tsumoto^1,2,3 (1.Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 2.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 3.Inst. of Med.Sci., Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-640(1T18a-12)] Conjugation of Synthetic TLR9 ligands to α-Mannose Immobilized Gold Nanoparticles for Enhanced Adjuvant Effects

^〇Koki Murata¹, Mayuko Shimoda², Mayumi Niimura², Masahiro Wakao¹, Yasuo Suda¹, Toshiro Moroishi^2,3, Hiroyuki Shinchi¹ (1.Graduate School of Science and Engineering., Kagoshima University, 2.Department of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, 3.Center for Metabolic Regulation of Healthy Aging, Faculty of Life Science, Kumamoto University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-641] Development of a Method to Control the Function of G4-forming Drug Modality IRDAptamer by Light Irradiation

^〇Mirai Suzuki¹, Akinori Banno¹, Masataka Mizunuma¹, Yuka Yamagata¹, Kazuhiro Furukawa², Yoshiro Chuman¹ (1.Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Niigata University, 2.Cell Regulation Laboratory in Biochemistry, Department of Chemistry, Faculty of Science, Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-642(1T18a-08)] Development of bispecific T-cell Engager antibody based cyclic single-chain antibodies

^〇Mizuki Ogawa¹, Mana Namikawa², Shosei Kai², Yifan Yang¹, Rui Shi¹, Kyo Okazaki¹, Hitoshi Maeda³, Hiroshi Watanabe ³, Toru Maruyama³, Takashi Sato¹, Yoshihiro Kobashigawa¹, Hiroshi Morioka¹ (1.Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2.Department of Analytical and Biophysical Chemistry, School of Pharmacy, Kumamoto University, 3.Department of Analytical and Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-687(1T18a-11)] Construction of VHH antibody display library using T7 phage and development of mirror image VHH antibody

^〇Kayu Maeda¹, Keisuke Aoki², Hiroaki Ohno², Jyoji Morise¹, Shogo Oka¹, Shinya Oishi³, Motohiro Nonaka¹ (1.Graduate School of Medicine, Kyoto University, 2.Graduate School of Pharmaceutical Sciences, Kyoto University, 3.Department of Medicinal Chemistry, Kyoto Pharmaceutical University )

The 96th Annual Meeting of the Japanese Biochemical Society