[2P-415(1T12a-03)] Development of methods for analyzing light-inducible interactions among the transcriptional co-regulators through intrinsic disordered regions (IDRs).

^〇Shun Sawatsubashi¹, Koichi Nishimura^1,2 (1.Institute of Advanced Medical Sciences, Tokushima University, 2.Graduate School of Biomedical Science, Tokushima University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-416(1T12a-07)] Creation of higher sequence-selective and timing-controlled m6A demethylation tool

^〇Kenko Otonari¹, Yuri Asami¹, Shiroh Futaki¹, Miki Imanishi¹ (Institute of Chemical Research, Kyoto Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-417] Understanding mechanisms of metabolic control by histone demethylase JMJD1A in adipose tissue

^〇Hina Sagae¹, Ryo Ito¹, Makoto Arai¹, Tumenjargal Myagmar¹, Hyunmi Choi¹, Takeshi Yoneshiro¹, Yoshihiro Matsumura¹, Juro Sakai^1,2 (1.Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine, 2.Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-418(1T12a-05)] Structural basis for the activation mechanism of DNMT1 in DNA methylation maintenance

^〇Amika Kikuchi¹, Hiroki Onoda^1,2, Kosuke Yamaguchi³, Satomi Kori¹, Atsushi Yamagata⁴, Atsuya Nishiyama⁵, Makoto Nakanishi⁵, Pierre-Antoine Defossez³, Kyohei Arita¹ (1.Grad. Sch. of Med Life Sci., YCU., 2.NUSR., Nagoya Univ., 3.Epi. and Cell Fate, CNRS., 4.RIKEN, BDR, 5.Inst. of Med. Sci., Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-419(1T12a-09)] Pioneer transcription factor FOXA and PRDM1 guarantee lineage fidelityby coordinating repressive chromatin state.

^〇Satoshi Matsui^1,2, Marissa Granitto^1,2,4, Morgan Buckley^1,2, Joseph Shiley^1,2, Hee-Woong Lim³, Makiko Iwafuchi^1,2,4 (1.Division of Developmental Biology, CCHMC, 2.Center for Stem Cell&Organoid Medicine (CuSTOM), CCHMC, 3.Division of Biomedical Informatics, CCHMC, 4.Department of Pediatrics, University of Cincinnati Collage of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-420] Analysis of the mechanism of human QSER1 gene expression

^〇Sota Akazawa¹, Yoko Ogino¹, Fumiaki Uchiumi¹ (Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-421] Structural dynamics of heterochromatin protein HP1 studied by spin labeling ESR spectroscopy: Effects of DNA, methylhistone peptide, phosphorylation and phase separation

^〇Isao Suetake¹, Kazunobu Sato², Tomoaki Sugishita³, Yuichi Mishima³, Takeji Takui², Hironobu Hojo³, Yoh Matsuki³, Toshimichi Fujiwara³, Makoto Miyata², Toshiaki Arata² (1.Fac. Nutritional Sci., Nakamura Gakuen Univ., 2.Osaka Met. Univ., 3.IPR. Osaka Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-422(1T12a-08)] Histone variant-specific chromatin remodeling activity catalyzed by Arabidopsis DDM1

^〇Akihisa Osakabe^1,2, Yoshimasa Takizawa³, Naoki Horikoshi³, Suguru Hatazawa³, Lumi Negishi³, Frederic Berger⁴, Tetsuji Kakutani¹, Hitoshi Kurumizaka³ (1.Department of Biological Sciences, The University of Tokyo, 2.JST PRESTO, 3.Institute for Quantitative Biosciences, The University of Tokyo, 4.Gregor Mendel Institute, Austrian Academy of Sciences, Vienna Biocenter)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-423] Mechanism of synovial sarcoma development by intrinsically disordered protein

^〇Eika Kan¹, Naoki Horikoshi², Kanami Takahashi¹, Kazutoshi Tani³, Yohei Miyanoiri⁴, Kaho Nakamoto⁵, Noriyuki Kodera⁶, Kowit Hengphasatporn⁷, Rie Suzuki¹, Ayane Shibuya¹, Satoshi Takenaka⁸, Yasuteru Shigeta⁷, Hitoshi Kurumizaka², Kenji Iwasaki⁹ (1.Grad. Sch. Sci. Tech., Univ. of Tsukuba, 2.IQB, The Univ. of Tokyo, 3.Grad. Sch. of Med., Mie Univ., 4.IPR, Osaka Univ., 5.Grad. Sch. Math. & Phys., Kanazawa Univ., 6.WPI-NanoLSI, Kanazawa Univ., 7.CCS, Univ. of Tsukuba, 8.OICI, 9.TARA, Univ. of Tsukuba)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-424] Chromatin regulation by histone variant H3.8

^〇Seiya Hirai^1,2, Tomoya Kujirai ¹, Yasuyuki Ohkawa³, Yoshimasa Takizawa¹, Hitoshi Kurumizaka^1,2 (1.Institute for Quantitative Biosciences, The University of Tokyo, 2.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 3.Medical Institute of Bioregulation, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society