[1P-304] Effect of sesamin metabolite (SC1) on the doxorubicin resistance of K562 human leukemia cells

^〇Shin Yomogida¹, Kazuhiro Watanabe², Akimasa Someya³, Saiko Kazuno⁴, Takashi Ueno⁴, Yoshiaki Miura⁴, Syuichi Kanno¹, Yuichi Ohkawara⁵, Tsutomu Fujimura⁶ (1.Division of Clinical Pharmacotherapeutics, Tohoku Med. and Pharm. Univ., 2.Division of Synthetic and Medicinal Chem., Tohoku Med. and Pharm. Univ., 3.Dept. of Biochem. And Systems Biomedicine, Juntendo Univ., Sch. of Med., 4.Lab. of Proteomics and BioMol. Sci., R. S.C., Juntendo Univ., Grad. Sch. of Med., 5.Division Pathological analysis, Tohoku Med. and Pharm. Univ., 6.Division of Bioanalytical Chem., Tohoku Med. and Pharm. Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-305] Molecular mechanism of degradation of apoptosis suppressor Mcl1 in rotenone-induced cell death

^〇Yuka Ito¹, Takaki Matsushita¹, Kenjiro Kawanaka¹, Tohru Komiya¹ (Graduate School of Bioscience, Nagahama Institute of Bioscience and Technology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-306(1T10a-06)] Elucidation of the molecular mechanism of the tumor-suppressive cell competition through the induction of a "kick-me-out" signal, FGF21

^〇Motoyuki Ogawa¹, Mina Yano¹, Isao Naguro¹, Hidenori Ichijo¹ (Cell Signaling, Grad. Sch. Pharmaceut. Sci., Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-307] Structural correlations of flavonoids that inhibit ferroptosis in mouse embryonic fibroblasts

^〇Momoko Sato¹, Emiri Kanomata², Shigetada Kato¹, Ayaki Shirai², Nahoko Kakihara², Mami Sato³, Hideyo Sato¹ (1.Niigata University Graduate School of Health Sciences, 2.Department of Medical Technology, Faculty of Medicine, Niigata University, 3.Sakeology Center, Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-308] JNK and p38 activation involvement in cSBL induced apoptosis for malignant mesothelioma cells

^〇Yoshito Sato¹, takeo Tatsuta¹, Shigeki Sugawara¹, Masahiro Hosono¹ (Div. Cell Recog., Tohoku Med. Pharm. Univ. )

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-309(1T10a-07)] A novel mechanism of ferroptosis execution mediated by Piezo1/TRP mechanosensitive channels

^〇Yusuke Hirata¹, Yoshiro Saito², Spencer Freeman³, Sergio Grinstein³, Atsushi Matsuzawa¹ (1.Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ., 2.Lab. of Mol. Biol. Metab., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ., 3.Program in Cell Biology, The Hospital for Sick Children, Toronto, Canada)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-310] Functional analysis of long noncoding RNAs that switch necrosis to apoptosis

^〇Tetsuya Miyoshi¹, Akira Sato¹ (Department of Biochemistry and Molecular Biology, Tokyo University of Science, Graduate School of Pharmaceutical Sciences.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-311] Effect of intracellular labile heme on ferroptosis

^〇Daisuke Tsuji¹, Tasuku Hirayama², Kanta Kawai², Hideko Nagasawa², Reiko Akagi² (1.Faculty of Pharmacy, Yasuda Women's University, 2.Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-312] The molecular mechanisms of necrosis induced by the synergistic action of Fas ligand and calcium ions

^〇Takumi Yokosawa¹, Yusuke Hirata¹, Takuya Noguchi¹, Atsushi Matsuzawa¹ (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-313] Sterols affect to neutrophil extracellular trap formation

^〇Yuichi Watanabe¹, Takashi Obama¹, Tomohiko Makiyama¹, Hiroyuki Itabe¹ (Div. Biol. Chem., Dept. Pharm. Sci., Showa Univ., Sch. Pharm.)

The 96th Annual Meeting of the Japanese Biochemical Society