[1T06a-10(2P-148)] Genome-wide CRISPR/Cas9 screening to identify factors for the lysosomal degradation of misfolded membrane proteins

^〇Kento Hagiya¹, Satoshi Hayakawa¹, Yuki Hayashi¹, Hidenori Ichijo¹ (Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:01 PM - 3:10 PM

[1T06a-11(1P-172)] Characterization of regulation mechanism of intrinsically weak affinity interactions of a multi-specific ligand PRELP through ECM localization

^〇Hirofumi Kosuge¹, Makoto Nakakido^1,2, Susana, de Vega³, Satoru Nagatoishi⁴, Tetsuya Fukuda⁵, Yasuhiko Bando⁵, Shin-ichi Ohnuma⁶, Kouhei Tsumoto^1,2,3,4 (1.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 2.Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 3.Inst. of Med. Sci., Univ. of Tokyo, 4.Med. Dev. Dev. Reg. Res. Center, Sch. of Eng., Univ. of Tokyo, 5.Biosys Technologies, 6.Inst. of Ophthalmology, Univ. College London)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:10 PM - 3:19 PM

[1T06a-12(2P-163)] Design of the artificial synapse connectors using Nanobodies against synaptic organizer MDGA1

^〇Takanori Yokoo¹, Makoto Nakakido^1,2, Keiko Matsuda³, Seisho Kinoshita², Michisuke Yuzaki³, Kouhei Tsumoto^1,2,4 (1.Dept of Chem &Biotech, Sch of Eng, Univ of Tokyo, 2.Dept of Bioeng, Sch of Eng, Univ of Tokyo, 3.Dept of Physiol, Keio Univ Sch of Med, 4.Inst of Med Sci, Univ of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:19 PM - 3:30 PM

[1T07a-01(1P-184)] Quantitative evaluation of DNA repair mechanism involving PARP-1 using the QCM method

^〇Shigeru Negi¹, Sakura Hosoi¹, Yuka Sato¹, Hiroyuki Furusawa², Masashi Mashimo¹, Yuka Nakagawa³ (1.Faculty of Pharmaceutical Sciences, Doshisha Women's University, 2.Institution for the promotion of general graduate education, Yamagata University, 3.Institute for Chemical Research, Kyoto University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:40 PM - 1:49 PM

[1T07a-02(1P-191)] Possibility of catalyzing decarboxylation by ubiquinone biosynthetic hydroxylase

^〇Miharu Konishi¹, Haruka Nagatani², Kimitoshi Sakamoto^2,3 (1.Graduate School of Agriculture and Life Science, Hirosaki Univ., 2.The United Graduate School of Agricultural Sciences, Iwate Univ., 3.Faculty of Agriculture and Life Science, Hirosaki Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:49 PM - 1:58 PM

[1T07a-03(1P-194)] Analysis of mammalian energy metabolism pathways using parasite specific metabolism enzymes

^〇Mizuki Hayashishita¹, Emi Ogasawara², Gloria Mavinga Bundutidi^3,4, Kohsuke Takeda⁵, Daniel Ken Inaoka^1,6,7, Kiyoshi Kita^1,6,8 (1.School of Tropical Medicine and Global Health, Nagasaki University, 2.Department of Biological Sciences, Graduate School of Science, Osaka University, 3.Graduate School of Biomedical Sciences, Nagasaki University, 4.Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 5.Department of Cell Regulation, Graduate School of Biomedical Sciences, Nagasaki University, 6.Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7.Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 8.Department of Host-Defense Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:58 PM - 2:07 PM

[1T07a-04(1P-196)] Function of Mycobacterium tuberculosis sulfide:quinone oxidoreductase

^〇Yuichi Matsuo^1,6, Tomoo Shiba², Kenji Iyoda², Uta Nakai², Akina Ota², Ken D. Inaoka^3,4,5, Kiyoshi Kita^3,5,6 (1.Department of Biomedical Laboratory Sciences, Graduate School of Health Sciences, Kumamoto University., 2.Department of Applied Biology, Graduate School of Science Technology, Kyoto Institute of Technology., 3.School of Tropical Medicine and Global Health, Nagasaki University., 4.Department of Molecular Infection Dynamics, Shionogi Global Infectious Diseases Division, Institute of Tropical Medicine (NEKKEN), Nagasaki University., 5.Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo., 6.Department of Host-Defense Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:07 PM - 2:16 PM

[1T07a-05(1P-350)] Activation of the urotensinII receptor by remdesivir induces cardiomyocyte dysfunction

^〇Akiko Ogawa¹, Seiya Ohira^1,2, Yuri Kato³, Tatsuya Ikuta⁴, Shota Yanagida^5,6, Xinya Mi³, Yukina Ishii³, Yasunari Kanda⁴, Motohiro Nishida^3,7, Asuka Inoue⁴, Fan-Yan Wei¹ (1. Department of Modomics Biology and Medicine, Institute of Development, Aging and Cancer (IDAC), Tohoku University, 2.Graduate School of Medicine, Tohoku University, 3.Department of Physiology, Graduate School of Pharmaceutical Sciences, Kyushu University, 4.Laboratory of Molecular & Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 5.Division of Pharmacology, National Institute of Health Sciences, 6.Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 7.National Institute for Physiological Sciences and Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:16 PM - 2:25 PM

[1T07a-06(2P-346)] Analysis of binding diversity and functional roles of GPCRs and β-arrestin

^〇Gaku Nakamura¹, Riku Kuwabara¹, Kouki Kawakami², Asuka Inoue¹ (1.Grad. Sch. of Pharm. Sci., Tohoku univ., 2.Grad. Sch. of Arts and Sciences., Tokyo Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:25 PM - 2:34 PM

[1T07a-07(1P-362)] A novel function of Ser/Thr phosphatase PPM1D on adipocyte differentiation and lipid droplet formation

^〇Sae Uno¹, Nozomi Kimura¹, Kazuyasu Sakaguchi¹, Rui Kamada¹ (Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:34 PM - 2:43 PM