[1P-314] Trametinib,a MEK inhibitor,overcomes resistance to EGFR-TKI in NSCLC

^〇Kenji Takeuchi¹, Yukito Seike¹, Saki Shimizu¹, Kazuto Tomimura¹, Ryuji Yamazawa¹, Kiyoshi Ito¹ (Fac. Pharm. Sci., Setsunan Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-315] Characterization of FerAb, a ferroptosis-detecting antibody, and its recombinant antibody

^〇Yuki Nishino¹, Sho Kobayashi^2,3, Takujiro Homma^3,4, Junichi Fujii³, Taro Tachibana¹, Chikako Yokoyama¹ (1.Department of Chemistry and Bioengineering, Graduate School of Engineering, Osaka Metropolitan University, 2. Department of Food, Life & Environmental Sciences, Faculty of Agriculture, Yamagata University, 3.Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 4.Department of Pharmacology, Graduate School of Medicine, Osaka Metropolitan University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-316] Ridaifen-B potentiates the anticancer effect of Gemcitabine on intractable cancer

^〇Youta Miura¹, Amane Yoneoka², Kyouka Komukai², Takatsugu Murata², Isamu Shiina², Takahisa Shinomiya¹, Shunsuke Takahashi¹, Yukitoshi Nagahara¹ (1.Dept. of Sci. Eng., Tokyo Denki Univ., 2.Dept. of Sci., Tokyo Univ. of Sci.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-317(1T10a-10)] The ER stress IRE1-XBP1 pathway maintains youthful skin through the regulation of epidermal stem cell proliferation

^〇Daniel Semmy¹, Kota Abe¹, Mizuki Honda², Shinya Oki², Yasuyuki Ohkawa³, Tohru Ishitani¹ (1.Dept. of Homeostatic Regulation, Research Institute of Microbial Diseases, Osaka University, 2.Dept. of Drug Discovery Medicine, Graduate School of Medicine, Kyoto University, 3.Div. of Transcriptomics, Medical Institute of Bioregulation, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-318] Changes of Heme oxygenase-1 Induction by Stress in THP-1 after differentiation

^〇Reiko Akagi¹, Nodoka Ishida¹, Daisuke Tsuji¹, Takafumi Miyamoto², Sachiye Inouye³ (1.Department of Pharmacy, Yasuda Women's University, 2.Department of Internal Medicine, University of Tsukuba, 3.Department of Pharmacy, Sanyo-Onoda City University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-319] Development of Viscosity-Responsive Probe and Effect of Osmotic Pressure on Lysosomal Microviscosity

^〇Junya Adachi¹, Toshiaki Fukushima^1,2, Haruka Oda², Hiroka Sugai³, Hiroshi Kimura^1,2, Kazushi Kinbara^1,3 (1.School of Life Science Technology, Tokyo Institute of Technology, 2.Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, 3.Living Systems Materialogy Research Group, International Research Frontiers Initiative, Tokyo Institute of Technology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-320] The roles of VPS4B in the response to nuclear envelope stress in cancer cells

^〇Zuqian Wu¹, Yasunao Kamikawa¹, Atsushi Saito¹, Kazunori Imaizumi¹ (Department of Biochemistry, Hiroshima University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-321] Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice

^〇Xiaokang Tang^1,2,3, Akiyuki Nishimura^1,2,3, Kohei Ariyoshi⁴, Kazuhiro Nishiyama⁴, Yuri Kato⁴, Yasunari Kanda⁵, Keitaro Umezawa⁶, Yasuteru Urano^7,8, Takaaki Akaike⁹, Motohiro Nishida^1,2,3,4 (1.National Institute of Natural Sciences, National Institute for Physiological Sciences, Department of Cardiovascular Signaling, 2.The Graduate University for Advanced Studies, School of Life Science, Department of Physiological Science, 3.National Institute of Natural Sciences, The Exploratory Research Center on Life and Living Systems, Cardiocirculatory Dynamism Research Group, 4.Graduate School of Pharmaceutical Sciences, Department of Physiology, 5.National Institute of Health Sciences, Division of Pharmacology, 6.Tokyo Metropolitan Institute of Gerontology, Research Team for Mechanism of Aging, 7.The University of Tokyo, Graduate School of Pharmaceutical Sciences, 8.The University of Tokyo, Graduate School of Medicine, 9.Tohoku University Graduate School of Medicine, Department of Environmental Medicine and Molecular Toxicology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-322] Effects of cultures with high pressure chamber on gene expressions of human cultured skeletal muscle cells and human cultured satellite cells

^〇Yasunobu Kawata¹, Kenji Watanabe¹, Yoichi Mizukami¹ (Institute of Gene Research Yamaguchi University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-323] Researches on the heat response of primary mouse dermal fibroblasts

^〇Lanyi Liu¹, TASUKU NAKAJIMA¹, Takeshi Miura¹, Taku Nedachi¹ (Toyo University)

The 96th Annual Meeting of the Japanese Biochemical Society