[2P-505] Development of the novel cancer therapy by regulation of tumor cell phagocytosis through the CD47-SIRPα system

^〇Takenori Kotani¹, Tomoko Takai², Satomi Komori², Yasuyuki Saito¹, Yoji Morata¹, Takashi Matozaki² (1.Div. Mol. & Cell. Signal., Kobe Univ. Grad. Sch. Med., 2.Div. Biosignal Reg., Kobe Univ. Grad. Sch. Med.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-506] Nucleic acid-derived nucleosides inhibit cancer cell proliferation via G1 arrest of cell cycle

^〇Akiko Kojima-Yuasa¹, Mamia Furuta¹, Nahoko Shiomi¹, Yutaro Sasaki¹, Keisuke Kiriyama², Keita Sutoh², Mica Fujita², Isao Matsui-Yuasa¹ (1.Department of Nutrition, Graduate School of Human Life and Ecology, Osaka Metropolitan University, 2.Fordays Co., Ltd.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-507] Creation of an assay system to validate inhibition of GIPC1/Syx complex formation in VEGF-A/NRP1 signaling.

^〇Sota Nakahara¹, Misuzu Seo^1,2, Nobuhiro Ueno² (1.Graduate School of Life Science, Kyoto Sangyo University, 2.Faculty of Life Science, Kyoto Sangyo University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-508] Analysis of the inhibitory effect of endoplasmic reticulum-associated degradation (ERAD) in cancer

^〇Ryouya Sugimoto¹, Sayaka Miura¹, Hidetoshi Fujita¹ (Osaka Institute of Technology, Faculty of Engineering, Department of Biomedical Engineering)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-509] Gemcitabine-resistant PDAC cells with DCK deficiency show upregulated expression of MYC and glutamine target genes.

^〇Suman Dash¹, Ueda Takeshi¹, Komuro Akiyoshi¹, Honda Masahiko¹, Okada Hitoshi¹ (Dept. of Biochemistry, Kindai Univ. Faculty of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-510] Novel Photochromic inhibitor of mitotic kinesin Eg5 exhibits multiple inhibitory activity states

^〇Md Alrazi Islam¹, TOSTANI FOFOU YONTA ², MARUTA SHINSAKU² (1.Faculty of Science and Engineering, Graduate School of Science and Engineering for Sustainable Innovation, Soka University, Hachioji, Tokyo, 2.Faculty of Science and Engineering, Graduate School of Bio Science, Soka University, Hachioji, Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-511] Nonredundant function of proteasome-tethered nucleoporin in glioblastoma

^〇Dini K Ikliptikawati^1,2,3, Hirai Nozomi^4,5, Makiyama Kei², Sabit Hemragul⁴, Kinoshita Masashi⁴, Matsumoto Koki ², Lim Keesiang³, Meguro-Horike Makiko⁶, Horike Shin-ichi⁶, Hazawa Masaharu^1,2,3, Nakada Mitsutoshi ⁴, Wong Richard W^1,2,3 (1.Cell-Bionomics Research Unit, Innovative Integrated Bio-Research Core, Institute for Frontier Science Initiative, Kanazawa University, 2.Laboratory of Molecular Cell Biology, Division of Transdisciplinary Sciences, Graduate School of Frontier Science Initiative, Kanazawa University, 3.WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, 4.Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan, 5.Department of Neurosurgery, Toho University Ohashi Medical Center, Tokyo, Japan, 6.Advanced Science Research Center, Institute for Gene Research, Kanazawa University, Kanazawa, Ishikawa, Japan)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-512] The functional implications of deamination in p65, a subunit of NF-κB, in oral squamous cell carcinoma.

^〇Yiran Tu¹, Ogura Ayano ², Jimi Eijiro ^1,3 (1.Sect Mol Cell Biochem,Kyushu Univ Grad Sch Dent, 2.Sect Aging Sci Pharmacol, Kyushu Univ Grad Sch Dent, 3.OBT Research Cent, Kyushu Univ Grad Sch Dent)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-513] Stress-Induced Premature Senescence and its Regulation from a Proteostasis Perspective: The Importance of Mitochondrial Metabolism

^〇Yasuhiro Takenaka^1,2, Ikuo Inoue², Masataka Hirasaki³, Masaaki Ikeda⁴, Yoshihiko Kakinuma¹ (1.Department of Bioregulatory Science, Graduate School of Medicine, Nippon Medical School, 2.Department of Diabetes and Endocrinology, Saitama Medical University, 3.Department of Clinical Cancer Genomics, International Medical Center, Saitama Medical University, 4.Department of Physiology, Saitama Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-514(1T14a-11)] Functional analysis of ASK1 in cellular senescence

^〇Takeru Odawara¹, Shota Yamauchi¹, Hidenori Ichijo¹ (Cell Signaling, Grad. Sch. of Pharmceut. Sci., Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society